H2N-PEG3-CH2COOtBu
- CAS No.
- 189808-70-6
- Chemical Name:
- H2N-PEG3-CH2COOtBu
- Synonyms
- tert-Butyl 2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)acetate;NH2-PEG3-C1-Boc;NH2-PEG3-CH2COOtBu;H2N-PEG3-CH2COOtBu;Amino-PEG3-CH2COOtBu;Amino-peg3-butyl ester;Amino-PEG3-CH2COOH t-Bu Ester;Amino-PEG3-CH2CO2-t-butyl ester;Acetic acid, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester;H2N-PEG3-CH2COOtBu/Acetic acid, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
- CBNumber:
- CB13340571
- Molecular Formula:
- C12H25NO5
- Molecular Weight:
- 263.33
- MDL Number:
- MFCD30730374
- MOL File:
- 189808-70-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 343.4±27.0 °C(Predicted) |
|---|---|
| Density | 1.041±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | Soluble in Water, DMSO, DCM, DMF |
| pka | 8.74±0.10(Predicted) |
| form | Liquid |
| color | Colorless to light yellow |
| InChI | InChI=1S/C12H25NO5/c1-12(2,3)18-11(14)10-17-9-8-16-7-6-15-5-4-13/h4-10,13H2,1-3H3 |
| InChIKey | OTTHWLFOQWLZKB-UHFFFAOYSA-N |
| SMILES | C(OC(C)(C)C)(=O)COCCOCCOCCN |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501 |
H2N-PEG3-CH2COOtBu price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0100052 | NH2-PEG3-C1-Boc ≥98% | 189808-70-6 | 100mg | $9 | 2026-06-04 | Buy |
| ChemScene | CS-0100052 | NH2-PEG3-C1-Boc ≥98% | 189808-70-6 | 250mg | $15 | 2026-06-04 | Buy |
| ChemScene | CS-0100052 | NH2-PEG3-C1-Boc ≥98% | 189808-70-6 | 1g | $47 | 2026-06-04 | Buy |
| ChemScene | CS-0100052 | NH2-PEG3-C1-Boc ≥98% | 189808-70-6 | 5g | $178 | 2026-06-04 | Buy |
| ChemScene | CS-0100052 | NH2-PEG3-C1-Boc ≥98% | 189808-70-6 | 25g | $882 | 2026-06-04 | Buy |
H2N-PEG3-CH2COOtBu Chemical Properties, Uses, Production
Description
Amino-PEG3-CH2CO2-t-butyl ester is a PEG molecule containing an amino group with a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group (t-Boc) can be deprotected under acidic conditions.
Uses
NH2-PEG3-C1-Boc (PROTAC Linker 5) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005
H2N-PEG3-CH2COOtBu Preparation Products And Raw materials
Raw materials
Preparation Products
H2N-PEG3-CH2COOtBu Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Huici Pharmaceutical Technology Co., LTD | 133-31922809 19372841038 | lixing@pharmahuici.com | China | 853 | 58 |
| Jiangxi Youken Biotechnology Co., Ltd. | 15107073929 | 1150046738@qq.com | China | 459 | 58 |
| Chengdu Pukang Biotechnology Co., Ltd | 18217049878 | cassie.gao@pu-kang.com | China | 480 | 58 |
| T&W GROUP | 021-61551611 13296011611 | contact@trustwe.com | China | 9884 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Hunan HuaTeng Pharmaceutical Co., Ltd., | 400-8592883 15367835770 | sales@huatengsci.com | China | 5869 | 58 |
| Mashilabs (Shanghai) Co.,Ltd. | 19916721580 | mafarm@126.com | China | 4534 | 58 |
| Borenpharm Co., Ltd | 027-65563561 | sales@borenpharm.com | China | 1245 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
View Latest Price from H2N-PEG3-CH2COOtBu manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-01-28 | NH2-PEG3-CH2COOtBu
189808-70-6
|
1g | 98% | 500kg | LAURENT | ||
 |
2025-05-07 | Amino-PEG3-CH2CO2-t-butyl ester
189808-70-6
|
$1500.00 | 1g | 98 | 5000 Kg | R&D Scientific Inc. |
-
- NH2-PEG3-CH2COOtBu
189808-70-6
- 98%
- LAURENT
-
- Amino-PEG3-CH2CO2-t-butyl ester
189808-70-6
- $1500.00
- 98
- R&D Scientific Inc.
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