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ChemicalBook >> CAS DataBase List >>1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose

1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose

1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose Structure
1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose structure
CAS No.
18968-05-3
Chemical Name:
1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose
Synonyms
1,3,4,6-Tetra-O<;beta-D-Mannopyranose tetraacetate;1,3,4,6-Tetra-O-acetyl-ββ-D-Mannopyranose 1,3,4,6-tetraacetate;1,3,4,6-Tetraacetate β-D-Mannopyranose;1,3,4,6-Tetra-O-acetyl-β-D-maopyranose;1,3,4,6-Tetra-O-acetyl-?D-mannopyranose;1,3,4,6-O-Tetraacetyl-β-D-Mannopyranose;β-d-mannopyranose 1,3,4,6-tetra-o-acetate;1,3,4,6-TETRA-O-ACETYL-SS-D-MANNOPYRANOSE
CBNumber:
CB1361140
Molecular Formula:
C14H20O10
Molecular Weight:
348.3
MDL Number:
MFCD00012354
MOL File:
18968-05-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:33:23
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1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose Properties

Melting point 160-161 °C(lit.)
Boiling point 425.5±45.0 °C(Predicted)
Density 1.33±0.1 g/cm3(Predicted)
refractive index -22.5 ° (C=1.4, CHCl3)
storage temp. Sealed in dry,2-8°C
solubility very faint turbidity in Chloroform
form powder to crystal
pka 12.22±0.70(Predicted)
color White to Almost white
optical activity [α]19/D 68°, c = 0.7 in pyridine
BRN 96634
InChI InChI=1/C14H20O10/c1-6(15)20-5-10-12(21-7(2)16)13(22-8(3)17)11(19)14(24-10)23-9(4)18/h10-14,19H,5H2,1-4H3/t10-,11+,12-,13-,14-/s3
InChIKey SHBHJRVMGYVXKK-XVIXHAIJSA-N
SMILES [C@@H]1(OC(=O)C)[C@@H](COC(=O)C)O[C@@H](OC(=O)C)[C@@H](O)[C@H]1OC(=O)C |&1:0,5,12,17,19,r|
CAS DataBase Reference 18968-05-3(CAS DataBase Reference)
UNSPSC Code 12352201
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
PPE Eyeshields, Gloves, type N95 (US)
Safety Statements  22-24/25
WGK Germany  3
HS Code  29400090
Storage Class 11 - Combustible Solids

1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose price More Price(49)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 310247 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose 98% 18968-05-3 100mg $170 2026-04-30 Buy
TCI Chemical T1459 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose >97.0%(GC) 18968-05-3 1g $118 2026-04-30 Buy
TCI Chemical T1459 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose >97.0%(GC) 18968-05-3 5g $355 2026-04-30 Buy
Biosynth MT02170 1,3,4,6-Tetra-O-acetyl-b-D-mannopyranose 18968-05-3 0.002kg $200.62 2026-06-04 Buy
Biosynth MT02170 1,3,4,6-Tetra-O-acetyl-b-D-mannopyranose 18968-05-3 0.005kg $334.36 2026-06-04 Buy
Product number Packaging Price Buy
310247 100mg $170 Buy
T1459 1g $118 Buy
T1459 5g $355 Buy
MT02170 0.002kg $200.62 Buy
MT02170 0.005kg $334.36 Buy

1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose Chemical Properties, Uses, Production

Uses

1,3,4,6-Tetra-o-acetyl-beta-d-mannopyranose is an intermediate in the preparation of precursors of 2-[18F]fluoro-2-deoxy-D-glucose for diagnostic use in positron emission tomography.

Synthesis

1 2-O-(1-ETHOXYETHYLIDENE)-BETA-D-MANNO&

28140-37-6

1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose

18968-05-3

General procedure for the synthesis of (2S,3S,4R,5R,6R)-6-(acetyloxymethyl)-3-hydroxytetrahydro-2H-pyran-2,4,5-triyl triacetate from 1,2-O-(1-ethoxyethylidene)-β-D-mannopyranose triacetate: to a solution of anhydrous acetone (27 mL) of the protoacid ester (4.4 g, 12 mmol), a slow addition of a 1 M aqueous hydrochloric acid (HCl) solution (2.7 mL), and the reaction was carried out under vigorous stirring (the water bath temperature was maintained at about 18 °C). The reaction mixture was continued to be stirred at room temperature for 5 min before being concentrated on a rotary evaporator, keeping the temperature below 20 °C. The concentrated solid was dissolved in chloroform (CHCl3, 25 mL) and washed with deionized water (2 x 10 mL). The organic phase was dried over anhydrous sodium sulfate (Na2SO4) and filtered, and the filtrate was concentrated on a rotary evaporator. The residue was ground with ether (Et2O) and recrystallized from ethanol (EtOH) to give the target product tetraacetylmannose (1.9 g, 45% yield) as a white solid. Thin layer chromatography (TLC) Rf value was 0.13 (unfolding agent: hexane/ethyl acetate = 1:1). The melting point is 134-136°C. High Resolution Mass Spectrometry (HRMS-ESI): m/z C14H20NaO10 ([M+Na]+) Calculated value 371.09542, measured value 371.09581 (error 0.39 mmu, 1.06 ppm).

References

[1] Bioorganic and Medicinal Chemistry, 2018, vol. 26, # 8, p. 1848 - 1858
[2] Tetrahedron, 1992, vol. 48, # 47, p. 10249 - 10264
[3] Tetrahedron Letters, 2013, vol. 54, # 17, p. 2190 - 2193

1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose synthesis

28140-37-6
18968-05-3
Synthesis of 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose from 1 2-O-(1-Ethoxyethylidene)-beta-D-manno&

1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose Preparation Products And Raw materials

Raw materials

1 2-O-(1-Ethoxyethylidene)-beta-D-manno& Water Hydrochloric acid Acetone

Preparation Products

1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose Suppliers

Global Suppliers ( 129)
Supplier Tel Email Country ProdList Advantage
Jinan Samuel Pharmaceutical Co., Ltd. 0531-88821801 15192360884 605818151@qq.com China 479 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55
TOKYO CHEMICAL INDUSTRY CO., LTD. 03-36680489 Sales-JP@TCIchemicals.com Japan 28364 80
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 22497 55
Supplier Advantage
Jinan Samuel Pharmaceutical Co., Ltd. 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Capot Chemical Co., Ltd 66
Chemsky (shanghai) International Co.,Ltd 60
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 55
TOKYO CHEMICAL INDUSTRY CO., LTD. 80
9ding chemical ( Shanghai) Limited 55

View Latest Price from 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose pictures 2026-09-15 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose
18968-05-3
 1KG 98%min HPLC 100KGS WUHAN FORTUNA CHEMICAL CO., LTD
1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose pictures 2026-03-20 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose
18968-05-3
 $10.00 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose pictures 2024-04-29 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose
18968-05-3
 $50.00 1kg 99.10% 50000kg Ouhuang Engineering Materials (Hubei) Co., Ltd

1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose Spectrum

1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose(18968-05-3)MS1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose(18968-05-3)1HNMR1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose(18968-05-3)13CNMR1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose(18968-05-3)IR11,3,4,6-Tetra-O-acetyl-β-D-mannopyranose(18968-05-3)IR21,3,4,6-Tetra-O-acetyl-β-D-mannopyranose(18968-05-3)Raman

18968-05-3 (1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose) Related Search:

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1,1,3-Trimethoxybutane 1,4-Diacetoxybutane 1,1,3-Triethoxypropane D-Lyxose 1,3-Butanediol diacetate
1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose 1,3,4,6-Tetra-O-acetyl-2-deoxy-D-glucopyranose 2-(2-hydroxyethoxy)ethyl acetate

1of4

1,3,4,6-TETRA-O-ACETYL-BETA-D-MANNOPYRANOSE 1,2,3,4-TETRA-O-ACETYL-BETA-D-MANNOPYRANOSE 1,3,4,6-Tetraacetate β-D-Mannopyranose 1,3,4,6-O-Tetraacetyl-β-D-Mannopyranose [(2R,3R,4R,5S,6S)-3,4,6-triacetyloxy-5-hydroxyoxan-2-yl]methyl acetate (2S,3S,4R,5R,6R)-6-(Acetoxymethyl)-3-hydroxytetrahydro-2H-pyran-2,4,5-triyl triacetate 1,3,4,6-Tetra-O-acetyl-&beta 1,3,4,6-Tetra-O-acetyl-?D-mannopyranose 1-O,3-O,4-O,6-O-Tetraacetyl-β-D-mannopyranose β-D-Mannopyranose 1,3,4,6-tetraacetate beta-D-Mannopyranose tetraacetate 1,3,4,6-Tetra-O-acetyl-β-D-maopyranose β-d-mannopyranose 1,3,4,6-tetra-o-acetate 1,3,4,6-TETRA-O-ACETYL-SS-D-MANNOPYRANOSE 1,3,4,6-TETRA-O-ACETYL-BETA-D-MANNOPYRANOSE 98+% 1,2,3,4-TETRA-O-ACETYL-SS-D-MANNOPYRANOSE β-D-Mannopyranose, 1, 3, 4, 6-tetraacetate18968-05-3 Β-D-MANNOPYRANOSE, 1, 3, 4, 6-TETRAACETATE 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose USP/EP/BP 1,3,4,6-Tetra-O< 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose, CAS 18968-05-3 1,3,4,6-Tetra-O-acetyl-β-D-pyridinylmannose 18968-05-3 C14H20O10 O-Substituted Sugars Sugars Carbohydrate Synthesis Specialty Synthesis Monosaccharides Intermediates & Fine Chemicals Labeling and Diagnostics Reagents Pharmaceuticals Carbohydrates & Derivatives Biochemistry O-Substituted Sugars Sugars chiral Glycon Biochem