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(R,S)-ANATABINE

(R,S)-ANATABINE Structure
(R,S)-ANATABINE structure
CAS No.
2743-90-0
Chemical Name:
(R,S)-ANATABINE
Synonyms
1,2,3,6-Tetrahydro-2,3'-bipyridine;1,2,3,6-Tetrahydro-2,3'-bipyridine;D,L-ANATABINE;rac-Anatabine;(±)-Anatabine;(R,S)-ANATABINE;Nicotine USP RC A;ANATABINE, (+/-)-(RG);(R,S)-Anatabine, 10 mM in DMSO;Nicotine Impurity A as Racemate
CBNumber:
CB1382628
Molecular Formula:
C10H12N2
Molecular Weight:
160.22
MDL Number:
MFCD00078278
MOL File:
2743-90-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-17 09:03:53
Product description Number Pack Size Price
Nicotine Related Compound A/EP Impurity A pharmaceutical secondary standard, certified reference material PHR3060 50MG $668
Nicotine Related Compound A United States Pharmacopeia (USP) Reference Standard 1463326 20mg $1340
(R,S)-Anatabine ≥95% 11001 5mg $41
(R,S)-Anatabine ≥95% 11001 10mg $69
(R,S)-Anatabine ≥95% 11001 50mg $266
More product size
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(R,S)-ANATABINE Properties

Boiling point 136
Density 1.045±0.06 g/cm3(Predicted)
storage temp. Amber Vial, Refrigerator, Under Inert Atmosphere
solubility ≤15mg/ml in DMSO;15mg/ml in dimethyl formamide
form solution in ethanol.
pka 8.84±0.40(Predicted)
color Light yellow to yellow
Stability Hygroscopic, Light Sensitive
Major Application pharmaceutical (small molecule)
InChI InChI=1S/C10H12N2/c1-2-7-12-10(5-1)9-4-3-6-11-8-9/h1-4,6,8,10,12H,5,7H2
InChIKey SOPPBXUYQGUQHE-UHFFFAOYSA-N
SMILES C1(C2=CC=CN=C2)NCC=CC1
CAS DataBase Reference 2743-90-0
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Danger
Hazard statements  H301-H319
Precautionary statements  P264-P270-P280-P301+P310-P305+P351+P338-P337+P313
Risk Statements  25-36
Safety Statements  24/25
RIDADR  2810
WGK Germany  WGK 3
HazardClass  IRRITANT
HS Code  29399990
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Oral
Eye Irrit. 2

(R,S)-ANATABINE price More Price(58)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR3060 Nicotine Related Compound A/EP Impurity A pharmaceutical secondary standard, certified reference material 2743-90-0 50MG $668 2026-04-30 Buy
Sigma-Aldrich 1463326 Nicotine Related Compound A United States Pharmacopeia (USP) Reference Standard 2743-90-0 20mg $1340 2026-04-30 Buy
Cayman Chemical 11001 (R,S)-Anatabine ≥95% 2743-90-0 5mg $41 2026-04-30 Buy
Cayman Chemical 11001 (R,S)-Anatabine ≥95% 2743-90-0 10mg $69 2026-04-30 Buy
Cayman Chemical 11001 (R,S)-Anatabine ≥95% 2743-90-0 50mg $266 2026-04-30 Buy
Product number Packaging Price Buy
PHR3060 50MG $668 Buy
1463326 20mg $1340 Buy
11001 5mg $41 Buy
11001 10mg $69 Buy
11001 50mg $266 Buy

(R,S)-ANATABINE Chemical Properties,Uses,Production

Description

(R,S)-Anatabine is a minor alkaloid produced in plants of the Solanaceae family, including tobacco. The detection of (R,S)-anatabine in urine is used as an indicator of tobacco use, particularly when nicotine-containing products (gum, patches, inhalers, and medications) are also being used. (R,S)-Anatabine increases nicotine self-administration and locomotor activity in rats. Of note, (R,S)-anatabine diminishes amyloid-β production in vitro and in vivo. (R,S)-Anatabine reduces (600 μg/ml) the transcription and protein levels of β-secretase, lowering the amount of Aβ (1-40) and Aβ (1-42) in a dose dependent manner in SHSY-5Y cells. (R,S)-Anatabine also dose dependently inhibits NF-κB activation.

Chemical Properties

Light Yellow Oil

Uses

A nicotine metabolite

Uses

A nicotine (N412420) metabolite.

Uses

(R,S)-Anatabine is a metabolite of Nicotine (N412420).

in vitro

anatabine dose-dependently lowered aβ1-40 and aβ1-42 levels and reduced sappβ production without any effects on sappα levels. anatabine lowered aβ production by mainly impacting the β-cleavage of app. anatabine lowered nfκb activation. anatabine inhibited bace-1 transcription and reduced bace-1 protein levels in human neuronal like shsy-5y cells. (r,s)-anatabine also dose dependently inhibits nf-κb activation [1].

in vivo

in a transgenic mouse model of alzheimer's disease, acute treatment with anatabine for 4 days significantly lowered brain soluble aβ1-40 and aβ1-42 levels [1].

References

[1] paris d, beaulieu-abdelahad d, bachmeier c, et al. anatabine lowers alzheimer's aβ production in vitro and in vivo[j]. european journal of pharmacology, 2011, 670(2): 384-391.

(R,S)-ANATABINE Preparation Products And Raw materials

Raw materials

Preparation Products

(R,S)-ANATABINE Suppliers

Global( 139)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29640 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19936 58
Nanjing jinheyou Trading Co., Ltd. 		15705188088 admin@jheyou.com CHINA 1268 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		+86-021-61551413 contact@trustwe.com China 5746 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32468 58
Career Henan Chemica Co 		+86-0371-86658258 +86-13203830695 laboratory@coreychem.com China 30224 58
Shanghai UCHEM Inc. 		+86-18930848214 +86-021-56762820 sales@myuchem.com China 8886 58
AFINE CHEMICALS LIMITED 		+86-571-85134551 +86-18958018566 info@afinechem.com China 15079 58
Finetech Industry Limited 		+86-27-8746-5837 +86-18627785180 info@finetechnology-ind.com China 9539 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
BOC Sciences 		58
Nanjing jinheyou Trading Co., Ltd. 		58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		58
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
Shanghai UCHEM Inc. 		58
AFINE CHEMICALS LIMITED 		58
Finetech Industry Limited 		58

View Lastest Price from (R,S)-ANATABINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(R,S)-Anatabine pictures 2026-07-17 (R,S)-Anatabine
2743-90-0
 $39.00-150.00 98.95% 10g TargetMol Chemicals Inc.
(R,S)-Anatabine pictures 2026-07-17 (R,S)-Anatabine
2743-90-0
 $39.00-150.00 98.95% 10g TargetMol Chemicals Inc.
(R,S)-ANATABINE pictures 2019-12-23 (R,S)-ANATABINE
2743-90-0
 1g 95%min 20kg/month Nanjing jinheyou Trading Co., Ltd.

(R,S)-ANATABINE Spectrum

(R,S)-ANATABINE(2743-90-0)1HNMR

2743-90-0((R,S)-ANATABINE)Related Search:

Neotuberostemonine (+/-)-ANABASINE 2,3'-Bipyridine (R,S)-ANATABINE-2,4,5,6-D4 S-(-)-ANATABINE
ANATABINE (R,S)-N-NITROSOANATABINE (R,S)-N-NITROSOANATABINE-2,4,5,6-D4 1-(3-METHYL-6-(5-METHYL-6-PHENYLPYRIDIN-3-YL)-2-PHENYL-5,6-DIHYDROPYRIDIN-1(2H)-YL)ETHANONE (R,S)-Anatabine-d4
5,5'-DIMETHYL-6,6'-DIPHENYL-1,2,3,6-TETRAHYDRO-2,3'-BIPYRIDINE 2-CHLORO-1-(3-METHYL-6-(5-METHYL-6-PHENYLPYRIDIN-3-YL)-2-PHENYL-5,6-DIHYDROPYRIDIN-1(2H)-YL)ETHANONE (R,S)-ANATABINE BITARTRATE (3-METHYL-6-(5-METHYL-6-PHENYLPYRIDIN-3-YL)-2-PHENYL-5,6-DIHYDROPYRIDIN-1(2H)-YL)(PHENYL)METHANONE (R,S)-ANATABINE

1of3

(R,S)-ANATABINE ANATABINE, (+/-)-(RG) (+/-)-Anatabine, 3-(1,2,3,6-Tetrahydropyridin-2-yl)pyridine, 2-(Pyridin-3-yl)-1,2,3,6-tetrahydropyridine Anatabine, froM Nicotiana tabacuM L. Anatabine, 97%, from Nicotiana tabacum L. 1,2,3,6-Tetrahydro-2,3'-bipyridine 98% Nicotine USP RC A 1,2,3,6-tetrahydro-2,3'-bipyridine dihydrochloride Nicotine USP Related Compound A (rac-Nicotine EP Impurity A) 2,3'-Bipyridine, 1,2,3,6-tetrahydro- Nicotine Impurity A as Racemate Nicotine EP Impurity A as Racemate (R,S)Anatabine,inhibit,(R,S)-Anatabine,(R,S) Anatabine,Inhibitor rac-Anatabine (R,S)-Anatabine 100μg/mL in Methanol (2RS)-1,2,3,6-Tetrahydro-2,3'-bipyridyl ((RS)-Anatabine) (R,S)-Anatabine, 10 mM in DMSO (±)-Anatabine 1,2,3,6-Tetrahydro-2,3'-bipyridine , (R,S)-Anatabine (R,S)-Anatabine(solution in ethanol) (2RS)-1,2,3,6-Tetrahydro-2,3'-bipyridyl ((RS)-Anatabine) rac-Anatabine (rac-Nicotine EP Impurity A, Nicotine USP Related Compound A) 1,2,3,6-Tetrahydro-2,3'-bipyridine 1,2,3,6-Tetrahydro-2,3'-bipyridine D,L-ANATABINE 2743-90-0 27430-90-0 Aromatics Heterocycles Metabolites & Impurities Metabolites Nicotine Derivatives