CARDIN
- CAS No.
- 477-32-7
- Chemical Name:
- CARDIN
- Synonyms
- visnadine;VISNADIN;Visnadine, mixture of dihydrosamidin and visnadin;Selva;CARDIN;cardine;carduben;carduben-s;CARDIN USP/EP/BP;Visnadine >=95% (LC/MS-ELSD)
- CBNumber:
- CB1386015
- Molecular Formula:
- C21H24O7
- Molecular Weight:
- 388.41
- MDL Number:
- MFCD31811647
- MOL File:
- 477-32-7.mol
| Melting point | 85-88° |
|---|---|
| alpha | D20 +9.2° (alc); D30 +42.5° (c = 2 in dioxane) |
| Boiling point | 434.13°C (rough estimate) |
| Density | 1.2086 (rough estimate) |
| refractive index | 1.5300 (estimate) |
| storage temp. | -20°C |
| form | solid |
| Major Application |
metabolomics vitamins, nutraceuticals, and natural products |
| Cosmetics Ingredients Functions | SKIN CONDITIONING |
| InChI | 1S/C21H24O7/c1-6-11(2)20(24)27-19-18(25-12(3)22)16-14(28-21(19,4)5)9-7-13-8-10-15(23)26-17(13)16/h7-11,18-19H,6H2,1-5H3/t11-,18-,19-/m1/s1 |
| InChIKey | GVBNSPFBYXGREE-CXWAGAITSA-N |
| SMILES | CC[C@@H](C)C(=O)O[C@@H]1[C@H](OC(C)=O)c2c(OC1(C)C)ccc3C=CC(=O)Oc23 |
| CAS DataBase Reference | 477-32-7 |
| EWG's Food Scores | 1 |
| NCI Dictionary of Cancer Terms | cardin |
| FDA UNII | 0RL4V0K263 |
| ATC code | C04AX24 |
| UNSPSC Code | 12352200 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H410 |
| Precautionary statements | P273-P301+P312+P330 |
| Hazard Codes | Xn,N |
| Risk Statements | 22-50 |
| Safety Statements | 61 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Acute 1 Aquatic Chronic 1 |
| Toxicity | LD50 in mice (mg/kg): 2240 orally; >370 s.c. (Erbring) |
CARDIN price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SMB00087 | Visnadine ≥95% (LC/MS-ELSD) | 477-32-7 | 1mg | $326 | 2026-04-30 | Buy |
| Biosynth | XV179459 | Visnadine, mixture of dihydrosamidin and visnadin | 477-32-7 | 10mg | $295 | 2026-06-05 | Buy |
| Biosynth | XV179459 | Visnadine, mixture of dihydrosamidin and visnadin | 477-32-7 | 50mg | $885 | 2026-06-05 | Buy |
| Biosynth | XV179459 | Visnadine, mixture of dihydrosamidin and visnadin | 477-32-7 | 100mg | $1416 | 2026-06-05 | Buy |
| Biosynth | XV179459 | Visnadine, mixture of dihydrosamidin and visnadin | 477-32-7 | 250mg | $2360 | 2026-06-05 | Buy |
CARDIN Chemical Properties, Uses, Production
Preparation
Crude CARDIN was thoroughly mixed with petroleum ether at a rate of 100 cc ether per kilogram of pectin. This produced a homogeneous pulp, which was then allowed to stand at approximately 150°C for 24 hours and subsequently filtered through a Buchner funnel to recover purified CARDIN in a yield of 85-90%.
Originator
Vibeline ,Bellon ,France,1960
Uses
Visnadine is used as a coumarin scaffold for anti-inflammatory drug development, melanin biosynthetic inhibitory activity, anticellulite efficacy in female patient with cellulite blemish affected by fat accumulation or new anticellulite treatment.
Definition
ChEBI: Visnadin is a member of coumarins.
Manufacturing Process
Ammi visnaga is a plant of the Umbelliferae family, which has been known and
used for its therapeutic properties by the peoples of the Mediterranean basin
since time immemorial.
Visnadine may be extracted from the umbels of Ammi visnaga by an organic
solvent having a boiling point less than 110°C. The resulting solution is
concentrated first by heating in a water bath and then is allowed to stand
some time at a temperature of about 20°C and if necessary is treated for
separation of gummy constituents therefrom, after which the solution is
concentrated under reduced pressure. Finally, the crude product is crystallized
and separated by retaining it on a filter.
This crude product may then, according to the process, be purified by mixing
it with petroleum ether and allowing it to stand at ordinary temperature, then
filtering it to obtain the pure visnadine.
Therapeutic Function
Coronary vasodilator, Antiarrhythmic
CARDIN Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3984 | 66 |
| Finetech Industry Limited | 027-87465837 19945049750 | sales@finetechnology-ind.com | China | 9331 | 58 |
| Shanghai Yongye Biotechnology Co., Ltd. | 86-021-61559134 15921386130 | 3423497944@qq.com | China | 8135 | 55 |
| Wuhan ChemFaces Biochemical Co., Ltd. | 18607101326 15172504745 | aileen@chemfaces.com | China | 6904 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shanghai ChengShao Biological Technology Co., Ltd. | 021-61847300 13341622919 | shcss01@163.com | China | 4806 | 58 |
| Nanjing Digger Medical Technology Co. Ltd. | 025-025-51191215 18013836722 | 2399235533@qq.com | China | 4932 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| Aktin Chemicals, Inc. | 028-85159085 | info@aktinchem.com | CHINA | 1025 | 58 |
