- CARDIN
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- $1.00
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2026-08-07
- CAS:477-32-7
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 350000KG
- Visnadine
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- $950.00
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2024-02-04
- CAS:477-32-7
- Min. Order: 1g
- Purity: 98
- Supply Ability: 20 Kg
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| Product Name: | CARDIN | | Synonyms: | (alpha-methylbutyryloxy)-3’-acetoxy-4’-dihydro-3’,4’-seselin;CARDIN;2h,8h-benzo(1,2-b:3,4-b’)dipyran-2-one-acetate;2-methyl-,9-esterwith9,10-dihydro-9,10-dihydroxy-8,8-dimethyl-butyricaci;3-(alpha-methylbutyryloxy)-4-acetoxy-3,4-dihydroseseline;cardine;carduben;carduben-s | | CAS: | 477-32-7 | | MF: | C21H24O7 | | MW: | 388.41 | | EINECS: | 207-515-1 | | Product Categories: | Coumarins | | Mol File: | 477-32-7.mol |  |
| | CARDIN Chemical Properties |
| Melting point | 85-88° | | alpha | D20 +9.2° (alc); D30 +42.5° (c = 2 in dioxane) | | Boiling point | 434.13°C (rough estimate) | | density | 1.2086 (rough estimate) | | refractive index | 1.5300 (estimate) | | storage temp. | -20°C | | form | solid | | Major Application | metabolomics
vitamins, nutraceuticals, and natural products | | Cosmetics Ingredients Functions | SKIN CONDITIONING | | InChI | 1S/C21H24O7/c1-6-11(2)20(24)27-19-18(25-12(3)22)16-14(28-21(19,4)5)9-7-13-8-10-15(23)26-17(13)16/h7-11,18-19H,6H2,1-5H3/t11-,18-,19-/m1/s1 | | InChIKey | GVBNSPFBYXGREE-CXWAGAITSA-N | | SMILES | CC[C@@H](C)C(=O)O[C@@H]1[C@H](OC(C)=O)c2c(OC1(C)C)ccc3C=CC(=O)Oc23 | | CAS DataBase Reference | 477-32-7 |
| Hazard Codes | Xn,N | | Risk Statements | 22-50 | | Safety Statements | 61 | | RIDADR | UN 3077 9 / PGIII | | WGK Germany | 3 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1 | | Toxicity | LD50 in mice (mg/kg): 2240 orally; >370 s.c. (Erbring) |
| | CARDIN Usage And Synthesis |
| Preparation | Crude CARDIN was thoroughly mixed with petroleum ether at a rate of 100 cc ether per kilogram of pectin. This produced a homogeneous pulp, which was then allowed to stand at approximately 150°C for 24 hours and subsequently filtered through a Buchner funnel to recover purified CARDIN in a yield of 85-90%. | | Originator | Vibeline ,Bellon ,France,1960 | | Uses | Visnadine is used as a coumarin scaffold for anti-inflammatory drug development, melanin biosynthetic inhibitory activity, anticellulite efficacy in female patient with cellulite blemish affected by fat accumulation or new anticellulite treatment. | | Definition | ChEBI: Visnadin is a member of coumarins. | | Manufacturing Process | Ammi visnaga is a plant of the Umbelliferae family, which has been known and
used for its therapeutic properties by the peoples of the Mediterranean basin
since time immemorial.
Visnadine may be extracted from the umbels of Ammi visnaga by an organic
solvent having a boiling point less than 110°C. The resulting solution is
concentrated first by heating in a water bath and then is allowed to stand
some time at a temperature of about 20°C and if necessary is treated for
separation of gummy constituents therefrom, after which the solution is
concentrated under reduced pressure. Finally, the crude product is crystallized
and separated by retaining it on a filter.
This crude product may then, according to the process, be purified by mixing
it with petroleum ether and allowing it to stand at ordinary temperature, then
filtering it to obtain the pure visnadine. | | Therapeutic Function | Coronary vasodilator, Antiarrhythmic |
| | CARDIN Preparation Products And Raw materials |
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