Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>1,2-Dioleoyl-3(S)-trimethylammoniumpropane (chloride)

1,2-Dioleoyl-3(S)-trimethylammoniumpropane (chloride)

1,2-Dioleoyl-3(S)-trimethylammoniumpropane (chloride) Structure
1,2-Dioleoyl-3(S)-trimethylammoniumpropane (chloride) structure
CAS No.
428506-51-8
Chemical Name:
1,2-Dioleoyl-3(S)-trimethylammoniumpropane (chloride)
Synonyms
1,2-Dioleoyl-3(S)-trimethylammoniumpropane (chloride)
CBNumber:
CB14033658
Molecular Formula:
C42H80ClNO4
Molecular Weight:
698.56
MDL Number:
MOL File:
428506-51-8.mol
MSDS File:
SDS
Last updated:2025-04-17 18:22:24
Request For Quotation

1,2-Dioleoyl-3(S)-trimethylammoniumpropane (chloride) Properties

solubility DMF: Slightly soluble; DMSO: Slightly soluble; Ethanol: 20 mg/ml
form A solid

1,2-Dioleoyl-3(S)-trimethylammoniumpropane (chloride) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 38195 1,2-Dioleoyl-3(S)-trimethylammoniumpropane (chloride) ≥95% 428506-51-8 50mg $112 2026-04-30 Buy
Cayman Chemical 38195 1,2-Dioleoyl-3(S)-trimethylammoniumpropane (chloride) ≥95% 428506-51-8 100mg $212 2026-04-30 Buy
Cayman Chemical 38195 1,2-Dioleoyl-3(S)-trimethylammoniumpropane (chloride) ≥95% 428506-51-8 250mg $445 2026-04-30 Buy
ChemScene CS-1098950 1,2-Dioleoyl-3(S)-trimethylammoniumpropane chloride 98.09% 428506-51-8 25mg $151 2026-06-04 Buy
ChemScene CS-1098950 1,2-Dioleoyl-3(S)-trimethylammoniumpropane chloride 98.09% 428506-51-8 50mg $240 2026-06-04 Buy
Product number Packaging Price Buy
38195 50mg $112 Buy
38195 100mg $212 Buy
38195 250mg $445 Buy
CS-1098950 25mg $151 Buy
CS-1098950 50mg $240 Buy

1,2-Dioleoyl-3(S)-trimethylammoniumpropane (chloride) Chemical Properties, Uses, Production

Description

1,2-Dioleoyl-3(S)-trimethylammoniumpropane (S-DOTAP) is a cationic lipid and the less immunologically active isomer of DOTAP .1,2 Lipoplexes containing S-DOTAP and encapsulating siRNA targeting the gene encoding aromatase, CYP19A1, decrease aromatase activity in MCF-7 breast cancer cells.1 Vaccination with a peptide epitope from human papillomavirus (HPV) 16 protein E7 in S-DOTAP-containing liposomes decrease tumor size but do not induce IFN-γ production by CD8+ T cells and tumor-infiltrating lymphocytes (TILs) in a murine cervical cancer model.2

Uses

1,2-Dioleoyl-3(S)-trimethylammoniumpropane chloride is a biochemical reagent.

References

1. Terp, M.C., Bauer, F., Sugimoto, Y., et al. Differential efficacy of DOTAP enantiomers for siRNA delivery in vitro Int. J. Pharm. 430(1-2),328-334(2012).
2. Vasievich, E.A., Chen, W., and Huang, L. Enantiospecific adjuvant activity of cationic lipid DOTAP in cancer vaccine Cancer Immunol. Immunother. 60(5),629-638(2011).

1,2-Dioleoyl-3(S)-trimethylammoniumpropane (chloride) Preparation Products And Raw materials

Raw materials

Preparation Products

1,2-Dioleoyl-3(S)-trimethylammoniumpropane (chloride) Suppliers

Global Suppliers ( 6)
Supplier Tel Email Country ProdList Advantage
Foshan Heshuo Pharm technology Co., ltd 15363639686 heshuoyiyao@hotmail.com China 2488 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
Tianjin Qige Technology Co., Ltd. 13012205621 304306732@qq.com China 296 58
Supplier Advantage
Foshan Heshuo Pharm technology Co., ltd 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Tianjin Qige Technology Co., Ltd. 58

428506-51-8 (1,2-Dioleoyl-3(S)-trimethylammoniumpropane (chloride)) Related Search:

1,2-Dipalmitoyl-3-trimethylammonium-propane DOTAP N-[1-(2,3-Dioleyloxy)propyl]-N,N,N-trimethylammonium chloride 1,2-Dioleoyl-3(R)-trimethylammoniumpropane (chloride) N,N,N-trimethyl-2,3-bis(stearoyloxy)propylammonium chloride
Solutol HS 15

1of2

1,2-Dioleoyl-3(S)-trimethylammoniumpropane (chloride) 428506-51-8