4'-BROMO-3-CHLOROPROPIOPHENONE
- CAS No.
- 31736-73-9
- Chemical Name:
- 4'-BROMO-3-CHLOROPROPIOPHENONE
- Synonyms
- Bupropion Impurity 45;3-chloro-4-bromopropiophenone;P-BROMO-3-CHLOROPROPIOPHENONE;4'-Bromo-β-chloropropiophenone;4'-Bromo-3-chloropropiophenone;4'-Bromo-3-chloropropiophenone;4-BROMO-BETA-CHLOROPROPIOPHENONE;4,4-diphenyloxazolidine-2,5-dione;4'-Bromo-3-chloropropiophenone,99%;4'-Bromo-3-chloropropiophenone,97%
- CBNumber:
- CB1450255
- Molecular Formula:
- C9H8BrClO
- Molecular Weight:
- 247.52
- MDL Number:
- MFCD00018979
- MOL File:
- 31736-73-9.mol
- MSDS File:
- SDS
| Melting point | 54-59 °C(lit.) |
|---|---|
| Boiling point | 333.8±27.0 °C(Predicted) |
| Density | 1.5182 (rough estimate) |
| vapor pressure | 0.016Pa at 25℃ |
| refractive index | 1.5963 (estimate) |
| Flash point | >230 °F |
| storage temp. | Sealed in dry,Room Temperature |
| form | powder |
| color | White |
| Water Solubility | 36mg/L at 20℃ |
| BRN | 1944367 |
| LogP | 3.2 at 22℃ |
| CAS DataBase Reference | 31736-73-9(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| RIDADR | UN1759 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2914790090 | |||||||||
| NFPA 704 |
|
4'-BROMO-3-CHLOROPROPIOPHENONE price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 545414 | 4′-Bromo-3-chloropropiophenone 95% | 31736-73-9 | 5g | $138 | 2023-06-20 | Buy |
| TRC | B698125 | 1-(4-Bromophenyl)-3-chloropropan-1-one | 31736-73-9 | 1g | $55 | 2021-12-16 | Buy |
| AK Scientific | J98062 | 1-(4-Bromophenyl)-3-chloropropan-1-one | 31736-73-9 | 25g | $55 | 2021-12-16 | Buy |
| Ark Pharm | AK-48143 | 1-(4-Bromophenyl)-3-chloropropan-1-one 98% | 31736-73-9 | 25g | $59 | 2021-12-16 | Buy |
| Oakwood | 002958 | 4'-Bromo-3-chloropropiophenone 98% | 31736-73-9 | 25g | $74 | 2021-12-16 | Buy |
4'-BROMO-3-CHLOROPROPIOPHENONE Chemical Properties,Uses,Production
Chemical Properties
light yellow to light brown crystalline powder
General Description
4′-Bromo-3-chloropropiophenone, a halogenated propiophenone derivative, is also known as 1-(4-bromophenyl)-3-chloro-1-propanone. Its molecular geometry has been studied based on density functional theory (DFT) calculations, FTIR and FT Raman spectra.
Flammability and Explosibility
Not classified
Synthesis
108-86-1
![1H-Inden-1-one, 5-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenyl]thio]-2,3-dihydro-](/CAS/20210305/GIF/161386-38-5.gif)
161386-38-5
625-36-5
31736-73-9
The general procedure for the synthesis of 4'-bromo-3-chloropropiophenone from bromobenzene, compound (CAS:161386-38-5) and 3-chloropropionyl chloride was as follows: first, a solution was prepared by dissolving 3-chloropropionyl chloride (15 mL) in methylene chloride (10 mL). Subsequently, the solution was slowly added to a stirring suspension of aluminum chloride (20.1 g) in methylene chloride (35 mL) and the mixture was stirred at room temperature for 15 minutes. Next, the dichloromethane (10 mL) mixture of bromobenzene (15 mL) was added in batches over a period of 1 hour. After addition, the reaction mixture continued to be stirred at room temperature for 16 hours. Upon completion of the reaction, the mixture was quenched by pouring it into a mixture of ice and 1N aqueous hydrochloric acid. The organic phase was separated, washed sequentially with water and saturated aqueous sodium bicarbonate, dried (using MgSO?), and the solvent evaporated. Finally, the residue was purified by column chromatography using a 15:1 mixture of petroleum ether and ethyl acetate as eluent to afford the target product 4-bromophenyl 2-chloroethyl ketone (27.9 g, 85% yield).
References
[1] Patent: US5332757, 1994, A
4'-BROMO-3-CHLOROPROPIOPHENONE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8617732866630 | abby@chuanghaibio.com | China | 8773 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 4000 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +8613288715578 | sales@hbmojin.com | China | 12347 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29800 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10035 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14360 | 58 |
View Lastest Price from 4'-BROMO-3-CHLOROPROPIOPHENONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-08-19 | 4'-BROMO-3-CHLOROPROPIOPHENONE
31736-73-9
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mujin Biotechnology Co.,Ltd | |
 |
2025-07-25 | 4'-BROMO-3-CHLOROPROPIOPHENONE
31736-73-9
|
US $0.00 / kg | 1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | |
 |
2025-06-24 | 4'-BROMO-3-CHLOROPROPIOPHENONE
31736-73-9
|
US $0.00-0.00 / KG | 1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- 4'-BROMO-3-CHLOROPROPIOPHENONE
31736-73-9
- US $0.00 / KG
- 99%
- Hebei Mujin Biotechnology Co.,Ltd
-
- 4'-BROMO-3-CHLOROPROPIOPHENONE
31736-73-9
- US $0.00 / kg
- 99%
- Shaanxi Dideu New Materials Co. Ltd
-
- 4'-BROMO-3-CHLOROPROPIOPHENONE
31736-73-9
- US $0.00-0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
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