3,3,3-Trifluoropropionic acid
- CAS No.
- 2516-99-6
- Chemical Name:
- 3,3,3-Trifluoropropionic acid
- Synonyms
- TFPA;cas no.:2516-99-6;RARECHEM AL BE 1046;Trifluoropropionicacid;TFPA 98% cas no 2516-99-6;Trifluoromethylacetic acid;3,3,3-TRIFLUOROPROPANOICACID;3,3,3-TRIFLUOROPROPIONIC ACID;3,3,3-Trifluoropropionnic acid;3,3,3-tri fluoropropaonic acid
- CBNumber:
- CB1451050
- Molecular Formula:
- C3H3F3O2
- Molecular Weight:
- 128.05
- MDL Number:
- MFCD00153292
- MOL File:
- 2516-99-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3,3,3-Trifluoropropionic acid 98% | 498203 | 5ml | $167 |
| 3,3,3-Trifluoropropionic acid 98% | 498203 | 25ml | $493.5 |
| 3,3,3-Trifluoropropionic Acid >98.0%(GC)(T) | T1713 | 1g | $27 |
| 3,3,3-Trifluoropropionic Acid >98.0%(GC)(T) | T1713 | 5g | $74 |
| 3,3,3-TrifluoropropanoicAcid | T792645 | 25g | $365 |
| More product size | |||
| Melting point | 9.7 °C (lit.) |
|---|---|
| Boiling point | 145 °C/746 mmHg (lit.) |
| Density | 1.45 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | >100°C |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | pK1:3.06 (25°C) |
| form | Liquid |
| color | Clear colorless |
| BRN | 1751796 |
| InChI | InChI=1S/C3H3F3O2/c4-3(5,6)1-2(7)8/h1H2,(H,7,8) |
| InChIKey | KSNKQSPJFRQSEI-UHFFFAOYSA-N |
| SMILES | C(O)(=O)CC(F)(F)F |
| CAS DataBase Reference | 2516-99-6(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314-H332-H412 | |||||||||
| Precautionary statements | P261-P273-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338 | |||||||||
| PPE | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 34 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | UN 3265 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Corrosive | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29159000 | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| Hazard Classifications | Acute Tox. 4 Inhalation Aquatic Chronic 3 Eye Dam. 1 Skin Corr. 1A |
|||||||||
| Limited Quantities | 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
3,3,3-Trifluoropropionic acid price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 498203 | 3,3,3-Trifluoropropionic acid 98% | 2516-99-6 | 5ml | $167 | 2025-07-31 | Buy |
| Sigma-Aldrich | 498203 | 3,3,3-Trifluoropropionic acid 98% | 2516-99-6 | 25ml | $493.5 | 2025-07-31 | Buy |
| TCI Chemical | T1713 | 3,3,3-Trifluoropropionic Acid >98.0%(GC)(T) | 2516-99-6 | 1g | $27 | 2025-07-31 | Buy |
| TCI Chemical | T1713 | 3,3,3-Trifluoropropionic Acid >98.0%(GC)(T) | 2516-99-6 | 5g | $74 | 2025-07-31 | Buy |
| TRC | T792645 | 3,3,3-TrifluoropropanoicAcid | 2516-99-6 | 25g | $365 | 2021-12-16 | Buy |
3,3,3-Trifluoropropionic acid Chemical Properties,Uses,Production
Chemical Properties
Clear colorless liquid
Uses
3,3,3-Trifluoropropionic acid may be used in the synthesis of:
- 2,2,2-trifluoroethyl 3,3,3-trifluoroprionate
- ethyl 3,3,3-trifluoroprionate
- N-trifluoropropionyl-D-mannosamine
- 3,3,3-trifluoropropanoyl chloride
Synthesis
3,3,3-Trifluoropropionic acid can be reduced to trifluoropropanal or trifluoropropanol by lithium aluminum hydride or sodium borohydride, or it can be reduced to trifluoropropanol by hydrogenation in the presence of Rh/C catalyst. The CF3 group of 3,3,3-trifluoropropionic acid is unstable and susceptible to hydrolysis under strong alkaline conditions, so 3,3,3-trifluoropropionic acid cannot be obtained by hydrolysis of trifluoropropionic acid esters under alkaline conditions, but can be prepared by hydrolysis under acidic conditions.
3,3,3-Trifluoropropionic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SHANGHAI FLUORORING PHARMACEUTICAL CO LTD | 17501600223 | sales@fluororing.com | China | 76 | 58 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | FandaChem@Gmail.com | China | 1400 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1445 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29831 | 58 |
| HaBo Hong Kong Co., Limited. | +86-25-18512596065 | info@habotech.com | CHINA | 933 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2950 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5742 | 58 |
View Lastest Price from 3,3,3-Trifluoropropionic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-06-03 | 3,3,3-Trifluoropropionic acid
2516-99-6
|
US $55.00-550.00 / kg | 10kg | 0.99 | 20tons | Zibo Hangyu Biotechnology Development Co., Ltd | |
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2025-04-04 | 3,3,3-Trifluoropropionic acid
2516-99-6
|
US $0.00-0.00 / KG | 1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd.
|
|
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2023-07-19 | 3,3,3-Trifluoropropanoic acid
2516-99-6
|
US $30.00 / KG | 1KG | 99% | 20 Tons | Wuhan wingroup Pharmaceutical Co., Ltd |
-

- 3,3,3-Trifluoropropionic acid
2516-99-6
- US $55.00-550.00 / kg
- 0.99
- Zibo Hangyu Biotechnology Development Co., Ltd
-

- 3,3,3-Trifluoropropionic acid
2516-99-6
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-

- 3,3,3-Trifluoropropanoic acid
2516-99-6
- US $30.00 / KG
- 99%
- Wuhan wingroup Pharmaceutical Co., Ltd
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