3-Bromo-pyrazolo[1,5-a]pyridine
- CAS No.
- 5910-12-3
- Chemical Name:
- 3-Bromo-pyrazolo[1,5-a]pyridine
- Synonyms
- 3-broMoH-pyrazolo[1,5-a]pyridine;3-Brompyrazolo[1,5-a]pyridin;3-Bromo-pyrazolo[1,5-a]pyridine;3-bromopyrazolo[1,5-a]pyridine(SALTDATA: FREE)
- CBNumber:
- CB1451252
- Molecular Formula:
- C7H5BrN2
- Molecular Weight:
- 197.03
- MDL Number:
- MFCD06661764
- MOL File:
- 5910-12-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 55 °C(Solv: ligroine (8032-32-4)) |
|---|---|
| Density | 1.69±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 0.56±0.30(Predicted) |
| Appearance | Off-white to gray Solid |
| InChI | InChI=1S/C7H5BrN2/c8-6-5-9-10-4-2-1-3-7(6)10/h1-5H |
| InChIKey | NMPZEHJXHWTZNI-UHFFFAOYSA-N |
| SMILES | C12=C(Br)C=NN1C=CC=C2 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933998090 |
3-Bromo-pyrazolo[1,5-a]pyridine price More Price(71)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 079295 | 3-Bromopyrazolo[1,5-a]pyridine 95+% | 5910-12-3 | 250mg | $541 | 2026-06-03 | Buy |
| Usbiological | 079295 | 3-Bromopyrazolo[1,5-a]pyridine 95+% | 5910-12-3 | 1g | $1108 | 2026-06-03 | Buy |
| Usbiological | 079295 | 3-Bromopyrazolo[1,5-a]pyridine 95+% | 5910-12-3 | 5g | $2677 | 2026-06-03 | Buy |
| AstaTech | 21536 | 3-BROMO-PYRAZOLO[1,5-A]PYRIDINE 97% | 5910-12-3 | 0.25G | $40 | 2026-04-30 | Buy |
| AstaTech | 21536 | 3-BROMO-PYRAZOLO[1,5-A]PYRIDINE 97% | 5910-12-3 | 1G | $104 | 2026-04-30 | Buy |
3-Bromo-pyrazolo[1,5-a]pyridine Chemical Properties, Uses, Production
Uses
3-Bromopyrazolo[1,5-a]pyridine is used as a pharmaceutical intermediate compound for the preparation of Hpk1 antagonists.
Synthesis
16205-46-2
5910-12-3
The general procedure for the synthesis of 3-bromopyrazolo[1,5-a]pyridine-3-carboxylic acid from pyrazolo[1,5-a]pyridine was as follows: N-bromosuccinimide (3.06 g, 17.22 mmol) and sodium bicarbonate (4.34 g, 51.66 mmol) were sequentially added to a N,N-dimethylformamide (40 mL) solution of pyrazolo[1,5-a]pyridine-3-carboxylic acid (2.81 g, 17.22 mmol) in a solution of N,N-dimethylformamide (40 mL). The reaction mixture was stirred at room temperature for 4 h and then poured into water (100 mL). The resulting suspension was extracted twice with ethyl acetate and the organic layers were combined and dried over anhydrous magnesium sulfate. After filtration, the solvent was removed by concentration under reduced pressure. The crude product was purified by fast column chromatography (eluent: hexane/ethyl acetate = 8:2) to afford the target product 3-bromopyrazolo[1,5-a]pyridine (2.58 g, 76% yield). Mass spectrum (LRMS) showed m/z: 197 ([M+1]+). 1H-NMR (250 MHz, CDCl3) δ: 6.8 (t, 1H), 7.2 (t, 1H), 7.5 (d, 1H), 7.9 (s, 1H), 8.4 (d, 1H).
References
[1] Patent: WO2011/101161, 2011, A1. Location in patent: Page/Page column 99
3-Bromo-pyrazolo[1,5-a]pyridine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Carlow Chemicals Co., Ltd. | 21-33526724 18930996265 | info@carlowchem.com | China | 1820 | 50 |
| Shanghai Huiyu Biological Technology Co., LTD | 17280940401 | huiyu_bio@126.com | China | 1079 | 58 |
| Cangzhou Dimai Technology Co., Ltd | 1351-2466848 13512466848 | hbdypharm@163.com | China | 290 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| ZEROSCHEM.CO.,LTD. | 10-61256048 13810278579; | sales@zeroschem.com | China | 1399 | 59 |
| Chemsky(shanghai)International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Shanghai Sphchem Co., Ltd. | 021-56491756 13512199871 | 2819742715@qq.com | China | 3994 | 55 |
| Wuhan ariel chemical Co., LTD. | 18986259541 18986259541 | sales@3stc.com | China | 3833 | 58 |
View Latest Price from 3-Bromo-pyrazolo[1,5-a]pyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-08-18 | 3-BROMO-PYRAZOLO[1,5-A]PYRIDINE
5910-12-3
|
1KG | 98% | 1000 KG | Shaanxi Dideu New Materials Co. Ltd | ||
![]() |
2019-07-10 | 3-BROMO-PYRAZOLO[1,5-A]PYRIDINE
5910-12-3
|
$3.00 | 1KG | 99% | 100kg | Career Henan Chemical Co |
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![3-BROMO-PYRAZOLO[1,5-A]PYRIDINE pictures](/ProductImageEN3/2026-08/Small/a9693ee7-09ae-4c16-ac16-a15455bccbae.jpg)
- 3-BROMO-PYRAZOLO[1,5-A]PYRIDINE
5910-12-3
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
![3-BROMO-PYRAZOLO[1,5-A]PYRIDINE pictures](https://img.chemicalbook.com/ProductImageEN/2019-7/Small/c86f53bf-8d06-43e7-a92e-ee3f6bbe0fe0.jpg)
- 3-BROMO-PYRAZOLO[1,5-A]PYRIDINE
5910-12-3
- $3.00
- 99%
- Career Henan Chemical Co





