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ESI-08

ESI-08 Structure
ESI-08 structure
CAS No.
301177-43-5
Chemical Name:
ESI-08
Synonyms
ESI-08;ESI-08, 10 mM in DMSO;EPAC2,cAMP,ESI08,ESI 08,exchange,proteins,EPAC,Ras,inhibit,EPAC1,ESI-08,Inhibitor;4-cyclohexyl-2-((2,5-dimethylbenzyl)thio)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile;5-Pyrimidinecarbonitrile, 4-cyclohexyl-2-[[(2,5-dimethylphenyl)methyl]thio]-1,6-dihydro-6-oxo-
CBNumber:
CB14718610
Molecular Formula:
C20H23N3OS
Molecular Weight:
353.48
MDL Number:
MFCD01313047
MOL File:
301177-43-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08
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ESI-08 Properties

storage temp. 4°C, protect from light
solubility DMSO : 100 mg/mL (282.90 mM; ultrasonic and warming and heat to 60°C)
form Solid
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

ESI-08 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 43208 ESI-08 ≥98% 301177-43-5 5mg $152 2026-04-30 Buy
Cayman Chemical 43208 ESI-08 ≥98% 301177-43-5 10mg $289 2026-04-30 Buy
Cayman Chemical 43208 ESI-08 ≥98% 301177-43-5 25mg $608 2026-04-30 Buy
Cayman Chemical 43208 ESI-08 ≥98% 301177-43-5 50mg $911 2026-04-30 Buy
Biosynth BMA17743 ESI-08 301177-43-5 5mg $250 2026-06-04 Buy
Product number Packaging Price Buy
43208 5mg $152 Buy
43208 10mg $289 Buy
43208 25mg $608 Buy
43208 50mg $911 Buy
BMA17743 5mg $250 Buy

ESI-08 Chemical Properties, Uses, Production

Uses

ESI-08 is a potent and selective EPAC antagonist, which can completely inhibit both EPAC1 and EPAC2 (IC50 of 8.4 μM) activity. ESI-08 selectively blocks cAMP-induced EPAC activation, but does not inhibit cAMP-mediated PKA activation[1].

ESI-08 Preparation Products And Raw materials

Raw materials

Preparation Products

ESI-08 Suppliers

Global Suppliers ( 23)
Supplier Tel Email Country ProdList Advantage
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4859 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai SuperLan Chemcial Technique Centre 0-2022843681 15618226720 chaolaichem@foxmail.com China 9996 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
cjbscvictory 13348960310 13348960310 3003867561@qq.com China 10233 58
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 5000 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 trendseenbio@gmail.com China 9067 58
Supplier Advantage
Shanghai Lollane Biological Technology Co.,Ltd. 55
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60
Shanghai SuperLan Chemcial Technique Centre 58
BOC Sciences 58
TargetMol Chemicals Inc. 58
cjbscvictory 58
Jinan Jiuli Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58

View Latest Price from ESI-08 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ESI-08 pictures 2026-07-15 ESI-08
301177-43-5
 $51.00-198.00 99.05% 10g TargetMol Chemicals Inc.
ESI-08 pictures 2026-07-15 ESI-08
301177-43-5
 $51.00-198.00 99.05% 10g TargetMol Chemicals Inc.
  • ESI-08 pictures
  • ESI-08
    301177-43-5
  • $51.00-198.00
  • 99.05%
  • TargetMol Chemicals Inc.
  • ESI-08 pictures
  • ESI-08
    301177-43-5
  • $51.00-198.00
  • 99.05%
  • TargetMol Chemicals Inc.

ESI-08 Spectrum

ESI-08(301177-43-5)1HNMR

301177-43-5 (ESI-08) Related Search:

2-(benzylsulfanyl)-5-(2-hydroxyethyl)-6-methyl-3,4-dihydropyrimidin-4-one ESI-08 5-(2-Hydroxyethyl)-6-methyl-2-[(4-methylbenzyl)sulfanyl]-4(3H)-pyrimidinone 6-(tert-Butyl)-2-[(2-methylbenzyl)sulfanyl]-4(3H)-pyrimidinone 2-(([1,1'-biphenyl]-4-ylmethyl)thio)-3,5,6,7-tetrahydro-4H-cyclopenta[d]pyrimidin-4-one
HJC0197

1of2

ESI-08 5-Pyrimidinecarbonitrile, 4-cyclohexyl-2-[[(2,5-dimethylphenyl)methyl]thio]-1,6-dihydro-6-oxo- EPAC2,cAMP,ESI08,ESI 08,exchange,proteins,EPAC,Ras,inhibit,EPAC1,ESI-08,Inhibitor ESI-08, 10 mM in DMSO 4-cyclohexyl-2-((2,5-dimethylbenzyl)thio)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile 301177-43-5