ChemicalBook >> CAS DataBase List >>R-Pralatrexate
R-Pralatrexate
- CAS No.
- 1320211-70-8
- Chemical Name:
- R-Pralatrexate
- Synonyms
- R-Pralatrexate;Pralatrexate, (R)-;L-Glutamic acid, N-[4-[(1R)-1-[(2,4-diamino-6-pteridinyl)methyl]-3-butyn-1-yl]benzoyl]-
- CBNumber:
- CB14798265
- Molecular Formula:
- C23H23N7O5
- Molecular Weight:
- 477.47
- MDL Number:
- MOL File:
- 1320211-70-8.mol
- MSDS File:
- SDS
Last updated:2025-04-18 09:51:43
| Density | 1.471±0.06 g/cm3(Predicted) |
|---|---|
| pka | 3.53±0.10(Predicted) |
| FDA UNII | 9CY33O2XLX |
R-Pralatrexate Chemical Properties, Uses, Production
Uses
(R)-Pralatrexate is the (R)-enantiomer of Pralatrexate (HY-10446). Pralatrexate is an antifolate and is a potent dihydrofolate reductasean (DHFR) inhibitor[1].
References
[1] Enrica Marchi, et al. Pralatrexate Is Synergistic With the Proteasome Inhibitor Bortezomib in in Vitro and in Vivo Models of T-cell Lymphoid Malignancies. Clin Cancer Res. 2010 Jul 15;16(14):3648-58. DOI:10.1158/1078-0432.CCR-10-0671
R-Pralatrexate Preparation Products And Raw materials
Raw materials
Preparation Products
R-Pralatrexate Suppliers
Global Suppliers ( 9)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Quality Control Solutions Ltd. | 0755-66853366 13670046396 | orders@qcsrm.com | China | 18188 | 56 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9909 | 65 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| Hubei Xinyang Medical Technology Co., Ltd | 15347293736 | 2853117764@yongstandards.com | China | 9999 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shandong Dayou Pharmaceutical Research and Development Co., Ltd. | hanfangpharma@126.com 15165037910 | hanfangpharma@126.com | China | 25800 | 58 |
| TLC Pharmaceutical Standards Ltd. | 18012923235 18012923235 | chinasales04@tlcstandards.com.cn | China | 7839 | 58 |
| Changzhou Xianglong Pharmaceutical Technology Co., Ltd., | 18915873328 18915873328 | sales@xianglongpharm.com | China | 11049 | 58 |
1320211-70-8 (R-Pralatrexate) Related Search:
R-Pralatrexate
Pralatrexate, (R)-
L-Glutamic acid, N-[4-[(1R)-1-[(2,4-diamino-6-pteridinyl)methyl]-3-butyn-1-yl]benzoyl]-
1320211-70-8
