Pomalidomide-PEG3-NH2 hydrochloride
- CAS No.
- 2380273-75-4
- Chemical Name:
- Pomalidomide-PEG3-NH2 hydrochloride
- Synonyms
- HCl NH2-PEG3-CH2CO-Poma;Thalidomide-4-amido-C1-PEG3-NH2 HCl;Pomalidomide-PEG3-NH2 hydrochloride;P933620 Pomalidomide-amino-PEG3-NH2 hydrochloride;2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]acetamide Hydrochloride;2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)acetamide hydrochloride;Acetamide, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-, hydrochloride (1:1)
- CBNumber:
- CB14846366
- Molecular Formula:
- C21H27ClN4O8
- Molecular Weight:
- 498.92
- MDL Number:
- MFCD32173776
- MOL File:
- 2380273-75-4.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
Pomalidomide-PEG3-NH2 hydrochloride price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| BroadPharm | bp-44906 | Pomalidomide-amido-PEG3-amine, HCl salt | 2380273-75-4 | 25MG | $120 | 2026-05-24 | Buy |
| BroadPharm | bp-44906 | Pomalidomide-amido-PEG3-amine, HCl salt | 2380273-75-4 | 50MG | $230 | 2026-05-24 | Buy |
| BroadPharm | bp-44906 | Pomalidomide-amido-PEG3-amine, HCl salt | 2380273-75-4 | 100MG | $410 | 2026-05-24 | Buy |
| BroadPharm | bp-44906 | Pomalidomide-amido-PEG3-amine, HCl salt | 2380273-75-4 | 250MG | $650 | 2026-05-24 | Buy |
| aablocks | AA024S7V | Pomalidomide-amino-PEG3-NH2 (hydrochloride) 97% | 2380273-75-4 | 50mg | $119 | 2026-06-01 | Buy |
Pomalidomide-PEG3-NH2 hydrochloride Chemical Properties, Uses, Production
Uses
Protein degrader builiding block Pomalidomide-PEG3-NH2 (HCl salt) enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant amine for reactivity with a carboxyl group on the target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant amine, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.
reaction suitability
reactivity: carboxyl reactive
reagent type: ligand-linker conjugate
IC 50
Cereblon
Pomalidomide-PEG3-NH2 hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Pomalidomide-PEG3-NH2 hydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Daicel Chiral Technologies (China)CO.,LTD | 021-50460086-9 15921403865 | han_yajun@dctc.daicel.com | China | 7909 | 65 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| SuZhou Medinoah Co.,LTD. | 0512-69561983 13914027025 | zhang_q@medinoah.com | China | 3925 | 58 |
| Jilin Province Woda Biotechnology Co., Ltd. | 13504435624 | 1927928688@qq.com | China | 1644 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shandong Territorial sea Biological Technology Co., LTD | 15092083467 | tangfenjiushililiang@leadhigh.com.cn | China | 2986 | 58 |
| Hangzhou FuRun Pharmaceutical Technology Co., Ltd | 15658004993 | 1900830611@qq.com | China | 980 | 58 |
| NewCan Biotech Limited | +86-0571-86912261 +86-15658003402 | sales@newcanbio.com | China | 1979 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59929 | 58 |
View Latest Price from Pomalidomide-PEG3-NH2 hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-08 | Pomalidomide-amino-PEG3-NH2 hydrochloride
2380273-75-4
|
$34.00 | 98.87% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-06-07 | Pomalidomide-PEG3-NH2 hydrochloride
2380273-75-4
|
100mg | >98.00% | 100mg | Xian confluore Biological Technology Co., Ltd. |
-
- Pomalidomide-amino-PEG3-NH2 hydrochloride
2380273-75-4
- $34.00
- 98.87%
- TargetMol Chemicals Inc.
-
- Pomalidomide-PEG3-NH2 hydrochloride
2380273-75-4
- $0.00
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
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