ISOMITRAPHYLLINE
- CAS No.
- 4963-01-3
- Chemical Name:
- ISOMITRAPHYLLINE
- Synonyms
- ISOMITRAPHYLLINE;7-Isomitraphylline;Isomitraphylline-RM;AJMALICIN OXINDOLE A;ISOMITRAPHYLLINE(SH);Ajmalicine oxindole A;(7S)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester;Spiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid, 1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2-oxo-, methyl ester, (1'S,3S,4'aS,5'aS,10'aR)-
- CBNumber:
- CB1490378
- Molecular Formula:
- C21H24N2O4
- Molecular Weight:
- 368.43
- MDL Number:
- MFCD03788776
- MOL File:
- 4963-01-3.mol
- MSDS File:
- SDS
| Boiling point | 555.2±50.0 °C(Predicted) |
|---|---|
| Density | 1.33±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility |
Acetonitrile: Slightly soluble: 0.1-1 mg/ml Chloroform: Sparingly soluble: 1-10 mg/ml |
| pka | 13.56±0.60(Predicted) |
| FDA UNII | XKC69MV51V |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H300 |
| Precautionary statements | P264-P270-P301+P310+P330-P405-P501 |
ISOMITRAPHYLLINE price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL89718 | Isomitraphylline phyproof? Reference Substance | 4963-01-3 | 10mg | $575 | 2026-04-30 | Buy |
| Cayman Chemical | 39452 | Isomitraphylline ≥98% | 4963-01-3 | 1mg | $69 | 2026-04-30 | Buy |
| Cayman Chemical | 39452 | Isomitraphylline ≥98% | 4963-01-3 | 5mg | $307 | 2026-04-30 | Buy |
| Cayman Chemical | 39452 | Isomitraphylline ≥98% | 4963-01-3 | 10mg | $546 | 2026-04-30 | Buy |
| ChemScene | CS-0078903 | Isomitraphylline | 4963-01-3 | 1mg | $446 | 2026-06-04 | Buy |
ISOMITRAPHYLLINE Chemical Properties, Uses, Production
Description
This Mitragyna alkaloid has been isolated from the leaves of M. speciosa Korth by Beckett and his colleagues. It is an amorphous solid which cannot be obtained crystalline. The base may be characterized as the picrate which forms pale yellow needles from MeOH, m.p. 223°C (dec.). A methylgroup, a methoxycarbonyl group and one imino group are present. The second nitrogen atom is tertiary.
Uses
Isomitraphylline is an oxoindole alkaloid derivied from amazonian plants and maintain medicinal benefits. Used in the treatment of ulcers, arthritis, etc.
Biological Activity
Isomitraphylline, an oxindole alkaloid, has potent anti-cancer activity.
References
[1] Beckett et al., J. Pharm. Pharmacol., 17,753 (1965)
[2] Beckett et ai., Planta Med., 14, 266 (1966)
[3] Structure:
[4] Finch, Taylor., J. Amer. Chem. Soc., 84,3871 (1962)
[5] Prepara tion:
[6] Seaton et al., Can. J. Chem., 38, 1035 (1960)
[7] [1] L DINAN. Assessment of natural products in the Drosophila melanogaster B(II) cell bioassay for ecdysteroid agonist and antagonist activities.[J]. Psychological Reports, 2001, 8 1: 321-342. DOI: 10.1007/pl00000859
[8] [2] NICOLE BACHER. Oxindole alkaloids from Uncaria tomentosa induce apoptosis in proliferating, G0/G1-arrested and bcl-2-expressing acute lymphoblastic leukaemia cells[J]. British Journal of Haematology, 2006, 132 5: 615-622. DOI: 10.1111/j.1365-2141.2005.05907.x
ISOMITRAPHYLLINE Preparation Products And Raw materials
Raw materials
Preparation Products
ISOMITRAPHYLLINE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BioBioPha Co., Ltd. | 0871-65217109 | y.liu@mail.biobiopha.com | China | 5641 | 65 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7717 | 56 |
| Wuhan ChemFaces Biochemical Co., Ltd. | 18607101326 15172504745 | aileen@chemfaces.com | China | 6904 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Chengdu Push Bio-Technology Co., Ltd. | 028-85370565-229 18080489829 | 18080489829@163.com | China | 8379 | 60 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 021-4009004166/18616739031 18616739031 | 3007523370@qq.com | China | 40000 | 58 |
| Nanjing Digger Medical Technology Co. Ltd. | 025-025-51191215 18013836722 | 2399235533@qq.com | China | 4932 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 57336 | 58 |
| Labnetwork lnc. | +86-27-50766799 +86-18062016861 | contact@labnetwork.com | China | 19981 | 58 |
View Latest Price from ISOMITRAPHYLLINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-22 | Isomitraphylline
4963-01-3
|
$740.00 | 10g | TargetMol Chemicals Inc. |
-
- Isomitraphylline
4963-01-3
- $740.00
- TargetMol Chemicals Inc.
