Oxindole
- CAS No.
- 59-48-3
- Chemical Name:
- Oxindole
- Synonyms
- INDOLIN-2-ONE;2-OXINDOLE;2-INDOLINONE;1,3-Dihydro-indol-2-one;1,3-DIHYDRO-2H-INDOL-2-ONE;Indoline-2-one;OXINDOL;OXINDOLE;NSC 274863;2-Indolone
- CBNumber:
- CB6160645
- Molecular Formula:
- C8H7NO
- Molecular Weight:
- 133.15
- MDL Number:
- MFCD00005711
- MOL File:
- 59-48-3.mol
- MSDS File:
- SDS
| Melting point | 123-128 °C(lit.) |
|---|---|
| Boiling point | 227 °C73 mm Hg(lit.) |
| Density | 1.1475 (rough estimate) |
| refractive index | 1.5282 (estimate) |
| Flash point | 194-196°C/17mm |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | 9.1g/l |
| pka | 14.77±0.20(Predicted) |
| form | Solid |
| color | Light Brown |
| Water Solubility | insoluble |
| BRN | 114692 |
| InChI | 1S/C8H7NO/c10-8-5-6-3-1-2-4-7(6)9-8/h1-4H,5H2,(H,9,10) |
| InChIKey | JYGFTBXVXVMTGB-UHFFFAOYSA-N |
| SMILES | O=C1Cc2ccccc2N1 |
| CAS DataBase Reference | 59-48-3(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 0S9338U62H |
| NIST Chemistry Reference | 2H-Indol-2-one, 1,3-dihydro-(59-48-3) |
| EPA Substance Registry System | Oxindol (59-48-3) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312a-P330-P501a | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| RIDADR | 2811 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | NM2080500 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29337900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
Oxindole price More Price(96)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | O9808 | 2-Oxindole 97% | 59-48-3 | 5g | $66.4 | 2026-04-30 | Buy |
| Sigma-Aldrich | PHR2443 | Diclofenac Impurity E Pharmaceutical Secondary Standard; Certified Reference Material | 59-48-3 | 100MG | $777 | 2026-04-30 | Buy |
| Sigma-Aldrich | O9808 | 2-Oxindole 97% | 59-48-3 | 25g | $78 | 2026-04-30 | Buy |
| TCI Chemical | O0272 | Oxindole >98.0%(GC) | 59-48-3 | 5g | $25 | 2026-04-30 | Buy |
| TCI Chemical | O0272 | Oxindole >98.0%(GC) | 59-48-3 | 25g | $72 | 2026-04-30 | Buy |
Oxindole Chemical Properties, Uses, Production
Chemical Properties
beige to yellowish-orange or pinkish-brown powder
Uses
Oxindole is considered as indole analogue, which shows pharmacological activity.
Uses
Indole analogue; shows pharmacological activity
Definition
ChEBI: Indolin-2-one is an indolinone carrying an oxo group at position 2. It is an indolinone and a gamma-lactam.
Hazard
Causes flaccid paralysis without anesthesia (usually neuromuscular blockage), changes in motor activity, and ataxia in oral and intraperitoneal lethal-dose studies of mice; May cause irritation; Harmful by ingestion.
Solubility in organics
Oxindole is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide (DMF), which should be purged with an inert gas. The solubility of oxindole in ethanol and DMF is approximately 10 mg/ml and approximately 3 mg/ml in DMSO. Oxindole is sparingly soluble in aqueous buffers.
Oxindole Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Dancheng Huatai Biotechnology Co., Ltd. | 13482210809 13482210809 | hli@3wpharm.com | China | 357 | 58 |
| Zhanhua Huibang Chemical Co., Ltd. | 13906149256 | 793211102@qq.com | China | 152 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | 021-50182298 021-50180596 | sales@boylechem.com | China | 2202 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| future industrial shanghai co., ltd | 400-0066400 13621662912 | sales@jonln.com | China | 1989 | 65 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
Related articles
- Synthesis of 2-Oxindole
- 2-Oxindole is a bicyclic nitrogen heterocycle with a carbonyl function at position 2 of the fused pyrrole ring, having two pos....
- Jan 24,2022
View Latest Price from Oxindole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-08 | Oxindole
59-48-3
|
$29.00 | 99.65% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-08-08 | Oxindole
59-48-3
|
$29.00 | 99.65% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-05-28 | Oxindole
59-48-3
|
$9.00 | 1KG | 99.9 | 1 ton | Hebei Chuanghai Biotechnology Co,.LTD |
