KPU-300
- CAS No.
- 1620692-60-5
- Chemical Name:
- KPU-300
- Synonyms
- KPU-300;2,5-Piperazinedione, 3-[(3-benzoylphenyl)methylene]-6-(2-pyridinylmethylene)-, (3Z,6Z)-
- CBNumber:
- CB14919802
- Molecular Formula:
- C24H17N3O3
- Molecular Weight:
- 395.41
- MDL Number:
- MOL File:
- 1620692-60-5.mol
- MSDS File:
- SDS
KPU-300 Chemical Properties, Uses, Production
Description
KPU-300 is a potent and selective antimicrotubule agent. KPU-300 exhibited a potent cytotoxicity with an IC50 value of 7.0 nM against HT-29 cells, by strongly binding to tubulin (K d = 1.3 μM) and inducing microtubule depolymerization.
Uses
KPU-300 (compound 6b) is a tubulin inhibitor. KPU-300 has potent cytotoxicity with an IC50 value of 7.0 nM against HT-29 cells[1].
References
[1] Yoshiki Hayashi, et al. Development of a new benzophenone-diketopiperazine-type potent antimicrotubule agent possessing a 2-pyridine structure. ACS Med Chem Lett. 2014 Jul 23;5(10):1094-8. DOI:10.1021/ml5001883
KPU-300 Preparation Products And Raw materials
Raw materials
Preparation Products
KPU-300 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Supplier | Advantage |
|---|---|
| BOC Sciences | 65 |
| TargetMol Chemicals Inc. | 58 |
