Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>Bay 61-3606

Bay 61-3606

Bay 61-3606 Structure
Bay 61-3606 structure
CAS No.
732983-37-8
Chemical Name:
Bay 61-3606
Synonyms
CS-2745;BAY-61-360;Bay 61-3606;SYK INHIBITOR IV;BAY 61-3606 free base;BAY 61-3606 (BAY61-3606);BAY 61-3606, 10 mM in DMSO;Syk Inhibitor IV, BAY 61-3606;Syk Inhibitor IV, BAY 61-3606 HCl;BAY 61-3606 hydrate hydrochloride
CBNumber:
CB1497948
Molecular Formula:
C20H18N6O3
Molecular Weight:
390.4
MDL Number:
MFCD18641826
MOL File:
732983-37-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:49:17
Request For Quotation

Bay 61-3606 Properties

Density 1.41
storage temp. 2-8°C
solubility H2O: soluble
form solid
color yellow
InChI 1S/C20H18N6O3/c1-28-15-6-5-12(10-16(15)29-2)14-11-17-22-8-9-26(17)20(24-14)25-19-13(18(21)27)4-3-7-23-19/h3-11H,1-2H3,(H2,21,27)(H,23,24,25)
InChIKey JWQOJVOKBAAAAR-UHFFFAOYSA-N
SMILES [n]21c(ncc2)cc(nc1Nc4ncccc4C(=O)N)c3cc(c(cc3)OC)OC
FDA UNII 61G8S0H9KX
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

WGK Germany  3
Storage Class 11 - Combustible Solids

Bay 61-3606 price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 574714 Syk Inhibitor IV, BAY 61-3606 - CAS 732938-37-8 - Calbiochem 732983-37-8 2mg $253 2026-04-30 Buy
Biosynth HEB98337 BAY 61-3606 732983-37-8 10mg $1067.3 2026-06-04 Buy
Biosynth HEB98337 BAY 61-3606 732983-37-8 25mg $1427.75 2026-06-04 Buy
Biosynth HEB98337 BAY 61-3606 732983-37-8 50mg $2570 2026-06-04 Buy
Biosynth HEB98337 BAY 61-3606 732983-37-8 100mg $3427 2026-06-04 Buy
Product number Packaging Price Buy
574714 2mg $253 Buy
HEB98337 10mg $1067.3 Buy
HEB98337 25mg $1427.75 Buy
HEB98337 50mg $2570 Buy
HEB98337 100mg $3427 Buy

Bay 61-3606 Chemical Properties, Uses, Production

Uses

Syk Inhibitor IV is an imidazopyrimidine inhibitor of Syk and Syk-mediated functions.

Definition

ChEBI: 2-[[7-(3,4-dimethoxyphenyl)-5-imidazo[1,2-c]pyrimidinyl]amino]-3-pyridinecarboxamide is a member of pyrimidines.

Biological Activity

Cell permeable: yes', 'Primary Target
Syk', 'Product competes with ATP.', 'Reversible: yes

in vivo

Bay 61-3606 (50 mg/kg; administered twice a week for two weeks by intraperitoneal injection) alone leads to more efficacious reductions than that of TNF-related apoptosis-inducing ligand (TRAIL; 10 mg/kg) alone in MCF-7 tumor xenograft-bearing BALB/c nude mice. Bay 61-3606 administered in TRAIL combination significantly reduces the volume of the xenografted tumor[4].

Animal Model:Female BALB/c nude mice (5 weeks old) bearing MCF-7 tumor xenograft[4]
Dosage:50 mg/kg
Administration:Injected intraperitoneally twice a week with Bay 61-3606 (50 mg/kg), TRAIL (10 mg/kg) or a combination of Bay 61-3606 (50 mg/kg) and TRAIL (10 mg/kg); TRAIL was given 2 h after the injection of Bay 61-3606; for two weeks
Result:Led to efficacious reductions in tumor growth.

Bay 61-3606 Preparation Products And Raw materials

Raw materials

Preparation Products

Bay 61-3606 Suppliers

Global Suppliers ( 81)
Supplier Tel Email Country ProdList Advantage
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5996 61
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4853 58
AdooQ BioScience, LLC +1 (866) 930-6790 info@adooq.com United States 2774 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3493 58
AdooQ Bioscience CHINA 025-58849295 info@adooq.cn China 2981 60
LETOPHARM LIMITED +86-21-5821 5861 sales@letopharm.com China 2374 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4864 55
SPIRO PHARMA eric_feng1954@126.com China 9239 55
Shanghai Haozhixiang Biotechnology Co., Ltd 526763801 13301653310 526763801@qq.com China 8010 55
Supplier Advantage
Chembest Research Laboratories Limited 61
MedChemexpress LLC 58
AdooQ BioScience, LLC 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
AdooQ Bioscience CHINA 60
LETOPHARM LIMITED 58
Sigma-Aldrich 80
Shanghai Lollane Biological Technology Co.,Ltd. 55
SPIRO PHARMA 55
Shanghai Haozhixiang Biotechnology Co., Ltd 55

View Latest Price from Bay 61-3606 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BAY 61-3606 pictures 2026-07-27 BAY 61-3606
732983-37-8
 $51.00-143.00 98.72% 10g TargetMol Chemicals Inc.
  • BAY 61-3606 pictures
  • BAY 61-3606
    732983-37-8
  • $51.00-143.00
  • 98.72%
  • TargetMol Chemicals Inc.

Bay 61-3606 Spectrum

BAY 61-3606(732983-37-8)MS

732983-37-8 (Bay 61-3606) Related Search:

Benzyl alcohol 2-Methoxyphenylacetic acid 4'-Hydroxyacetophenone Sodium benzoate Bay 61-3606
Imidazo[1,2-c]pyrimidine, 7-methyl- (9CI)

1of2

BAY 61-3606 free base CS-2745 Syk Inhibitor IV, BAY 61-3606: sc-202351 hydrochloride Syk Inhibitor IV, BAY 61-3606 HCl BAY 61-3606 hydrate hydrochloride 2-[[7-(3,4-Dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]-3-pyridinecarboxamide BAY-61-360 Syk Inhibitor IV, BAY 61-3606 SYK INHIBITOR IV 3-Pyridinecarboxamide, 2-[[7-(3,4-dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]- Spleen tyrosine kinase,Syk,inhibit,BAY 61 3606,Apoptosis,Inhibitor,BAY 613606,BAY 61-3606 2-((7-(3,4-Dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl)amino)nicotinamide 2-{[7-(3,4-dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino}pyridine-3-carboxamide BAY 61-3606, 10 mM in DMSO BAY 61-3606 (BAY61-3606) Bay 61-3606 732983-37-8