Phenamil methanesulfonate
- CAS No.
- 1161-94-0
- Chemical Name:
- Phenamil methanesulfonate
- Synonyms
- MHPIZTURFVSLTJ-UHFFFAOYSA-N;2-Pyrazinecarboxamide, 3,5-diamino-6-chloro-N-[imino(phenylamino)methyl]-, methanesulfonate (1:1)
- CBNumber:
- CB1502107
- Molecular Formula:
- C13H16ClN7O4S
- Molecular Weight:
- 401.8
- MDL Number:
- MFCD00274070
- MOL File:
- 1161-94-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| storage temp. | 2-8°C |
|---|---|
| solubility | 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble2.5mg/mL |
| form | solid |
| color | yellow |
| Water Solubility |
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 2.5mg/mL DMSO: ≥5mg/mL (with warming) 0.1 M HCl: insoluble H2O: insoluble |
| InChI | 1S/C12H12ClN7O.CH4O3S/c13-8-10(15)19-9(14)7(18-8)11(21)20-12(16)17-6-4-2-1-3-5-6;1-5(2,3)4/h1-5H,(H4,14,15,19)(H3,16,17,20,21);1H3,(H,2,3,4) |
| InChIKey | MHPIZTURFVSLTJ-UHFFFAOYSA-N |
| SMILES | CS(O)(=O)=O.Nc1nc(N)c(nc1Cl)C(=O)NC(=N)Nc2ccccc2 |
| CAS DataBase Reference | 1161-94-0 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, type N95 (US) |
|---|---|
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
Phenamil methanesulfonate price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P203 | Phenamil methanesulfonate salt solid | 1161-94-0 | 5mg | $144 | 2026-04-30 | Buy |
| Sigma-Aldrich | P203 | Phenamil methanesulfonate salt solid | 1161-94-0 | 25mg | $489 | 2026-04-30 | Buy |
| Cayman Chemical | 14308 | Phenamil (methanesulfonate) ≥98% | 1161-94-0 | 5mg | $69 | 2026-04-30 | Buy |
| Cayman Chemical | 14308 | Phenamil (methanesulfonate) ≥98% | 1161-94-0 | 10mg | $95 | 2026-04-30 | Buy |
| Cayman Chemical | 14308 | Phenamil (methanesulfonate) ≥98% | 1161-94-0 | 50mg | $393 | 2026-04-30 | Buy |
Phenamil methanesulfonate Chemical Properties, Uses, Production
Chemical Properties
off-white to yellow solid
Uses
Phenamil Methanesulfonate Salt induced differentiation and peroxisome proliferator-activator receptor γ expression through ETS variant 4 in mouse preadipocyte
Uses
Phenamil methanesulfonate salt has been used:
- to stimulate adipocyte differentiation in 3T3 cells
- to test its effect on lateral flagella expression in Vibrio shilonii
- in nanoparticle preparation to test its effect on osteo/odontoblastic differentiation
General Description
Phenamil, a derivative of amiloride is an inhibitor of sodium channels including acid sensing ion channel (ASIC) and epithelial sodium channels (ENaC).
Biochem/physiol Actions
Phenamil is an inducer of peroxisome proliferator-activated receptor γ (PPARγ) and inhibits diamine oxidase. By favoring tribbles homolog 3 (Trb3) expression, phenamil holds therapeutic potential to treat pulmonary artery hypertension (PAH) and idiopathic PAH. It is also a bone morphogenetic protein (BMP) activator, which favors osteogenesis and odontogenesis of stem cells.
storage
Store at +4°C
Phenamil methanesulfonate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Weijiahe Biotechnology Co., Ltd | 17502176150; 17502176150 | 861873257@qq.com | China | 2676 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8039 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8435 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Jinan Yaoyan Pharmaceutical Co., Ltd. | jnyaoyan@163.com | China | 3057 | 58 | |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 57336 | 58 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19087 | 58 |
View Latest Price from Phenamil methanesulfonate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-24 | PHENAMIL METHANESULFONATE
1161-94-0
|
1KG | 99.0% | 10 tons | Shaanxi Dideu Medichem Co. Ltd |
-
- PHENAMIL METHANESULFONATE
1161-94-0
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
