6-CHLORO-2-PYRAZINECARBOXAMIDE
- CAS No.
- 36070-79-8
- Chemical Name:
- 6-CHLORO-2-PYRAZINECARBOXAMIDE
- Synonyms
- 6-Chloropyrazine-2-carboxamide;6-Chloropyrazinecarboxamide;2-Chloro-6-pyrazinecarboxamide;6-CHLORO-2-PYRAZINECARBOXAMIDE;PyrazinecarboxaMide, 6-chloro-;2-Pyrazinecarboxamide, 6-chloro-;6-Chloropyrazine-2-carboxylic acid amide;6-chloro-2-pyrazinecarboxamide(SALTDATA: FREE)
- CBNumber:
- CB51110693
- Molecular Formula:
- C5H4ClN3O
- Molecular Weight:
- 157.56
- MDL Number:
- MFCD02258395
- MOL File:
- 36070-79-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 6-Chloro-2-pyrazinecarboxamide AldrichCPR | CBR02075 | 1 g | $276 |
| 6-Chloropyrazine-2-carboxamide | LBA07079 | 2.5g | $472 |
| 6-Chloropyrazine-2-carboxamide 97% | AS26885 | 1g | $172 |
| 6-Chloropyrazine-2-carboxamide 97% | AS26885 | 5g | $576 |
| 6-Chloropyrazine-2-carboxamide | 143891 | 250.00mg | $44 |
| More product size | |||
| Melting point | 180-182℃ |
|---|---|
| Density | 1.478±0.06 g/cm3 (20 ºC 760 Torr) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | solid |
| InChI | 1S/C5H4ClN3O/c6-4-2-8-1-3(9-4)5(7)10/h1-2H,(H2,7,10) |
| InChIKey | JEERXOCCQAMKAF-UHFFFAOYSA-N |
| SMILES | O=C(N)C1=NC(Cl)=CN=C1 |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Sens. 1 |
6-CHLORO-2-PYRAZINECARBOXAMIDE price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | CBR02075 | 6-Chloro-2-pyrazinecarboxamide AldrichCPR | 1 g | $276 | 2026-04-30 | Buy | |
| Biosynth | LBA07079 | 6-Chloropyrazine-2-carboxamide | 36070-79-8 | 2.5g | $472 | 2026-06-04 | Buy |
| Activate Scientific | AS26885 | 6-Chloropyrazine-2-carboxamide 97% | 36070-79-8 | 1g | $172 | 2026-06-04 | Buy |
| Activate Scientific | AS26885 | 6-Chloropyrazine-2-carboxamide 97% | 36070-79-8 | 5g | $576 | 2026-06-04 | Buy |
| Matrix Scientific | 143891 | 6-Chloropyrazine-2-carboxamide | 36070-79-8 | 250.00mg | $44 | 2026-05-18 | Buy |
6-CHLORO-2-PYRAZINECARBOXAMIDE Chemical Properties,Uses,Production
Synthesis
23688-89-3
36070-79-8
Intermediate 13-2: Synthesis of 6-chloropyrazine-2-carboxamide 6-Chloropyrazine-2-carboxylic acid (2.00 g, 12.62 mmol) was dissolved in DMF (7 mL) and the solution was cooled to -40 °C. Under stirring, N-methylpyrrolidone (NMP, 2.77 mL, 25.23 mmol) and isobutyl chloroformate (3.27 mL, 25.23 mmol) were added sequentially. After controlling the reaction temperature to slowly rise to -20 °C over 20 min, ammonia (NH4OH) was added. A precipitate rapidly formed in the reaction mixture and after continued stirring for 15 min, the precipitate was collected by filtration and washed with cold water. Purification by recrystallization from ethanol (EtOH) afforded the title compound 6-chloropyrazine-2-carboxamide (670 mg, 34% yield) as light brown needle-like crystals. The product was characterized by 1H NMR (500 MHz, DMSO-d6): δ 7.93 (br s, 1H), 8.24 (br s, 1H), 8.99 (s, 1H), 9.12 (s, 1H).
References
[1] Patent: WO2009/81195, 2009, A1. Location in patent: Page/Page column 77
[2] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 2, p. 450 - 453
6-CHLORO-2-PYRAZINECARBOXAMIDE Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53799 | 58 |
| Zjartspharm Co., Ltd | 15068876005 | jocelynpan@zjarts.com | China | 9957 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Shanghai Cuisen Pharmaceutical Technology Co., Ltd. | 13472757003 | yongnan.wang@cendrix.cn | China | 970 | 65 |
| Kohn & Shawn Pharmatech Co.,Ltd | 0943-8293106 | sales@kyxpharma.com | China | 297 | 55 |
