ChemicalBook >> CAS DataBase List >>2,4-Dichlorothiazole

2,4-Dichlorothiazole

CAS No.
4175-76-2
Chemical Name:
2,4-Dichlorothiazole
Synonyms
2,4-DICHLOROTHIAZOLE;2,4-Dichlorothiazole>Thiazole, 2,4-dichloro-;2,4-DICHLORO-1,3-THIAZOLE;2,4-Dichlorothiazole ,98%;2,4-Dichloro-1,3-thiazole 96%;2,4-Dichlorothiazole(WX636073);2,4-DICHLOROTHIAZOLE,98.0+%(GC)
CBNumber:
CB1512175
Molecular Formula:
C3HCl2NS
Molecular Weight:
154.02
MDL Number:
MFCD08691358
MOL File:
4175-76-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:42:12

2,4-Dichlorothiazole Properties

Melting point 44 °C
Boiling point 184 °C
Density 1.603±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility soluble in Methanol
pka -1.93±0.10(Predicted)
form powder to crystal
color White to Light yellow to Light orange
InChI 1S/C3HCl2NS/c4-2-1-7-3(5)6-2/h1H
InChIKey ICETWLGKJXCIDX-UHFFFAOYSA-N
SMILES ClC1=NC(Cl)=CS1
CAS DataBase Reference 4175-76-2(CAS DataBase Reference)
UNSPSC Code 12352200
NACRES NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  WGK 3
HazardClass  IRRITANT
HS Code  29339900
Storage Class 11 - Combustible Solids

2,4-Dichlorothiazole price More Price(68)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich KOB0068 2,4-Dichloro-1,3-thiazole 4175-76-2 1g $191 2026-04-30 Buy
TCI Chemical D3549 2,4-Dichlorothiazole >98.0%(GC) 4175-76-2 5g $59 2026-04-30 Buy
TCI Chemical D3549 2,4-Dichlorothiazole >98.0%(GC) 4175-76-2 25g $176 2026-04-30 Buy
Activate Scientific AS30527 2,4-Dichlorothiazole 97% 4175-76-2 5g $22 2026-06-04 Buy
Activate Scientific AS30527 2,4-Dichlorothiazole 97% 4175-76-2 25g $46 2026-06-04 Buy
Product number Packaging Price Buy
KOB0068 1g $191 Buy
D3549 5g $59 Buy
D3549 25g $176 Buy
AS30527 5g $22 Buy
AS30527 25g $46 Buy

2,4-Dichlorothiazole Chemical Properties, Uses, Production

Chemical Properties

White solid

Synthesis

2,4-Thiazolidinedione

2295-31-0

2,4-Dichlorothiazole

4175-76-2

The general procedure for the synthesis of 2,4-dichlorothiazole from 2,4-thiazolidinedione was as follows: 2,4-thiazolidinedione (50 g, 0.43 mol) was dissolved in phosphorus trichloride (240 mL) and cooled to 5 °C. Pyridine (34 mL, 0.43 mol) was added slowly over 15 minutes. The reaction mixture was heated to 125°C and maintained at this temperature for 4 hours. After completion of the reaction, it was cooled to 22°C. Excess phosphorus trichloride was removed by vacuum distillation. The residue was slowly poured into water (1 L) pre-cooled to 5°C. The aqueous phase was extracted with dichloromethane (3 x 400mL). The organic phases were combined and the solvents were evaporated to give the target product 2,4-dichlorothiazole (50 g, 76% yield).EI/MS m/z: (35Cl35Cl/35Cl37Cl/37Cl37Cl)153/155/157(M+1)+.

References

[1] Patent: WO2008/36579, 2008, A1. Location in patent: Page/Page column 36-37
[2] Patent: US2005/234046, 2005, A1. Location in patent: Page/Page column 60
[3] Journal of the American Chemical Society, 2013, vol. 135, # 5, p. 1986 - 1996
[4] Patent: WO2013/149362, 2013, A1. Location in patent: Page/Page column 55
[5] Patent: WO2017/155909, 2017, A1. Location in patent: Paragraph 0159

2295-31-0
4175-76-2
Synthesis of 2,4-Dichlorothiazole from 2,4-Thiazolidinedione
Global Suppliers ( 164)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd. 21-57721279 18121011378 sales@shydchem.com.cn China 998 56
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64

View Latest Price from 2,4-Dichlorothiazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,4-Dichlorothiazole pictures 2021-07-13 2,4-Dichlorothiazole
4175-76-2
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
2,4-Dichlorothiazole pictures 2019-07-06 2,4-Dichlorothiazole
4175-76-2
$2.00 1KG 99% Career Henan Chemical Co
2,4-Dichlorothiazole ,98% 2,4-DICHLORO-1,3-THIAZOLE 2,4-DICHLOROTHIAZOLE Thiazole, 2,4-dichloro- 2,4-DICHLOROTHIAZOLE,98.0+%(GC) 2,4-Dichlorothiazole(WX636073) 2,4-Dichloro-1,3-thiazole 96% 2,4-Dichlorothiazole> 4175-76-2 C3HCl2NS Heterocyclic Compounds Thiazoles