2,4-Thiazolidinedione
- CAS No.
- 2295-31-0
- Chemical Name:
- 2,4-Thiazolidinedione
- Synonyms
- THIAZOLIDINE-2,4-DIONE;TZD;Thiazolidinedione;2,4-Thiazolidindione;U 25560;idinedione;usafek-5496;2,4-ThiazoL;USAF ek-5496;AURORA 23272
- CBNumber:
- CB6675365
- Molecular Formula:
- C3H3NO2S
- Molecular Weight:
- 117.13
- MDL Number:
- MFCD00005478
- MOL File:
- 2295-31-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 125-127 °C (lit.) |
|---|---|
| Boiling point | 178-179 °C (19 mmHg) |
| Density | 1.408 (estimate) |
| vapor pressure | 0Pa at 25℃ |
| refractive index | 1.5130 (estimate) |
| Flash point | 178-179°C/19mm |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Crystalline Powder |
| pka | 6.50±0.10(Predicted) |
| color | Slightly yellow |
| Water Solubility | Soluble in water (30 mg/ml at 3°C), methanol, DMSO, ethanol, and ethyl ether. |
| BRN | 110700 |
| InChI | 1S/C3H3NO2S/c5-2-1-7-3(6)4-2/h1H2,(H,4,5,6) |
| InChIKey | ZOBPZXTWZATXDG-UHFFFAOYSA-N |
| SMILES | O=C1CSC(=O)N1 |
| LogP | -0.29 at 25℃ |
| CAS DataBase Reference | 2295-31-0(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | AA68LXK93C |
| NIST Chemistry Reference | 2,4-Thiazolidinedione(2295-31-0) |
| EPA Substance Registry System | 2,4-Thiazolidinedione (2295-31-0) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P264-P270-P301+P310a-P321-P405-P501a | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 24/25-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | XJ5775000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29341000 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| REACH Registrations | Inactive | |||||||||
| NFPA 704 |
|
2,4-Thiazolidinedione price More Price(81)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 375004 | 2,4-Thiazolidinedione technical grade, 90% | 2295-31-0 | 25g | $86.7 | 2026-04-30 | Buy |
| Sigma-Aldrich | 375004 | 2,4-Thiazolidinedione technical grade, 90% | 2295-31-0 | 100g | $135 | 2026-04-30 | Buy |
| TCI Chemical | T1990 | 2,4-Thiazolidinedione >98.0%(GC)(T) | 2295-31-0 | 25g | $18 | 2026-04-30 | Buy |
| TCI Chemical | T1990 | 2,4-Thiazolidinedione >98.0%(GC)(T) | 2295-31-0 | 100g | $48 | 2026-04-30 | Buy |
| Usbiological | T3775-05 | 2,4-Thiazolidinedione (Thiazolidine-2,4-dione) | 2295-31-0 | 50g | $389 | 2026-06-04 | Buy |
2,4-Thiazolidinedione Chemical Properties, Uses, Production
Chemical Properties
White to Off-White Powder
Uses
Inhibitor of enzyme
Uses
2,4-Thiazolidinedione may be used in the synthesis of sixteen 5-arylidene-2,4-thiazolidinediones, via ultrasound-promoted aldol condensation reaction. It may be used as starting material for the synthesis of drugs with antihyperglycemic activity.
Definition
ChEBI: A thiazolidenedione carrying oxo substituents at positions 2 and 4.
General Description
2,4-Thiazolidinedione is a well-known peroxisome proliferator-activated receptors (PPAR) activator. Its effect on aging process using kidneys from Fischer 344 rats has been reported. A library of conjugates of 2,4-thiazolidinedione has been synthesized by Knoevenagel condensation followed by reduction using hydrogen gas and Pd/C catalyst. Knoevenagel condensation of various aromatic aldehydes with 2,4-thiazolidinedione in polyethylene glycol-300 has been reported.
Flammability and Explosibility
Not classified
2,4-Thiazolidinedione Preparation Products And Raw materials
Raw materials
Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing Whale Technology Corporation Ltd. | 010-83694934 13671295325 | sales@whalecorporation.com | China | 107 | 58 |
| Shandong XuanHong Biopharmaceutical Co., Ltd. | 0531-88801869 15090917080 | xuanhongchem@163.com | China | 144 | 58 |
| Anhui Dexinjia Biopharm Co., Ltd | 0531-82375893 15553111391 | phoebe@jndxj.com | China | 285 | 58 |
| shandong XuanHong Pharmaceutical Technology Co.,Ltd | +86-0531-88801869 15090917080 | 2955128025@qq.com | China | 294 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| future industrial shanghai co., ltd | 400-0066400 13621662912 | sales@jonln.com | China | 1989 | 65 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
View Latest Price from 2,4-Thiazolidinedione manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-17 | 2,4-Thiazolidinedione
2295-31-0
|
$50.00-1000.00 | 1KG | 0.99 | 10MT per month | Jinan Dexinjia Bio&Tech Co., Ltd | |
 |
2026-08-25 | 2,4-Thiazolidinedione
2295-31-0
|
$65.00-650.00 | 1KG | 0.99 | 20 tons | Zibo Hangyu Biotechnology Development Co., Ltd | |
 |
2026-08-20 | 2,4-Thiazolidinedione
2295-31-0
|
$1.10 | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited |
-
- 2,4-Thiazolidinedione
2295-31-0
- $50.00-1000.00
- 0.99
- Jinan Dexinjia Bio&Tech Co., Ltd
-
- 2,4-Thiazolidinedione
2295-31-0
- $65.00-650.00
- 0.99
- Zibo Hangyu Biotechnology Development Co., Ltd
-
- 2,4-Thiazolidinedione
2295-31-0
- $1.10
- 99.9%
- Dideu Industries Group Limited
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