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1-(2-Phenylethyl)piperazine

1-(2-Phenylethyl)piperazine Structure
1-(2-Phenylethyl)piperazine structure
CAS No.
5321-49-3
Chemical Name:
1-(2-Phenylethyl)piperazine
Synonyms
AKOS BBS-00003639;PHENETHYLPIPERAZINE;RARECHEM AH CK 0154;1-PHENETHYLPIPERAZINE;N-Phenethylpiperazine;1-phenylethylpiperazine;1-(2-Phenethyl)piperazine;N-(2-PHENYLETHYL)PIPERAZINE;N-(beta-Phenylethyl)piperazine;Piperazine, 1-(2-phenylethyl)-
CBNumber:
CB1667972
Molecular Formula:
C12H18N2
Molecular Weight:
190.28
MDL Number:
MFCD00040740
MOL File:
5321-49-3.mol
MSDS File:
SDS
Last updated:2026-09-12 18:49:20
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1-(2-Phenylethyl)piperazine Properties

Melting point 75-77°C
Boiling point 276 °C(lit.)
Density >1.006 g/mL at 20 °C(lit.)
refractive index n20/D 1.5430(lit.)
Flash point >230 °F
solubility DMSO (Slightly), Methanol (Slightly)
form liquid
pka 9.20±0.10(Predicted)
color Clear
Sensitive Air Sensitive
BRN 145893
CAS DataBase Reference 5321-49-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Skull and Crossbones (GHS06)
GHS05,GHS06
Signal word  Danger
Hazard statements  H318-H301-H314
Precautionary statements  P280-P305+P351+P338-P310-P260h-P301+P330+P331-P303+P361+P353-P405-P501a
Hazard Codes  C,Xn,Xi
Risk Statements  22-34
Safety Statements  26-36/37/39-45
RIDADR  UN 2922 8/PG 3
WGK Germany  2
F  10-34
Hazard Note  Irritant
HazardClass  8
HS Code  29335990
Limited Quantities 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
1
3 0

1-(2-Phenylethyl)piperazine price More Price(47)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 287720 1-(2-Phenylethyl)piperazine Asreported 5321-49-3 10g $360 2026-06-03 Buy
Usbiological 287720 1-(2-Phenylethyl)piperazine Asreported 5321-49-3 25g $531 2026-06-03 Buy
Usbiological 287720 1-(2-Phenylethyl)piperazine Asreported 5321-49-3 50g $744 2026-06-03 Buy
Usbiological 287720 1-(2-Phenylethyl)piperazine Asreported 5321-49-3 100g $1027 2026-06-03 Buy
Usbiological 287720 1-(2-Phenylethyl)piperazine Asreported 5321-49-3 250g $1593 2026-06-03 Buy
Product number Packaging Price Buy
287720 10g $360 Buy
287720 25g $531 Buy
287720 50g $744 Buy
287720 100g $1027 Buy
287720 250g $1593 Buy

1-(2-Phenylethyl)piperazine Chemical Properties,Uses,Production

Chemical Properties

Light yellow liquid

Uses

1-(2-Phenylethyl)piperazine is used to prepare non-imidazole human histamine H4 receptor antagonists. it is also used to synthesize imidazopyridine derivatives as inhibitors of Aurora kinases.

1-(2-Phenylethyl)piperazine synthesis

110-85-0
622-24-2
5321-49-3
Synthesis of 1-(2-Phenylethyl)piperazine from Piperazine and Phenethyl chloride

1-(2-Phenylethyl)piperazine Preparation Products And Raw materials

Raw materials

(2-Bromoethyl)benzene Ethanol Sodium chloride Toluene 1-(2-Phenylethyl)piperazine
Chloroform Piperazine Ethyl acetate Hydrochloric acid Dichloromethane
Sodium hydroxide Magnesium sulfate piperazinium chloride 1-phenyl-2-(piperazin-1-yl)ethanone Phenethyl chloride
1,2-Ethanediyl, 1-phenyl- (9CI)

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Preparation Products

1-(1-Phenylethyl)piperazine

1-(2-Phenylethyl)piperazine Suppliers

Global( 90)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Syntechem Co.,Ltd info@syntechem.com China 12973 57
Amatek Scientific Co. Ltd. 0512-56316828 4008675858 sales@amateksci.com China 9849 55
Chengdu HuaXia Chemical Reagent Co. Ltd 400-1166-196 13458535857 cdhxsj@163.com China 13323 58
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Alfa Aesar 84
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Beijing Ouhe Technology Co., Ltd 60
Shanghai Hanhong Scientific Co.,Ltd. 64
Syntechem Co.,Ltd 57
Amatek Scientific Co. Ltd. 55
Chengdu HuaXia Chemical Reagent Co. Ltd 58

View Lastest Price from 1-(2-Phenylethyl)piperazine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-(2-Phenylethyl)piperazine pictures 2022-11-04 1-(2-Phenylethyl)piperazine
5321-49-3
 $10.00 1G 99.99% 1000kg Hebei Ningnan Trade Co. LTD
1-(2-Phenylethyl)piperazine CAS 5321-49-3 pictures 2021-07-02 1-(2-Phenylethyl)piperazine CAS 5321-49-3
5321-49-3
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
1-(2-Phenylethyl)piperazine CAS 5321-49-3 pictures 2019-01-15 1-(2-Phenylethyl)piperazine CAS 5321-49-3
5321-49-3
$10.00 10KG 99% 10MT Hubei XinRunde Chemical Co., Ltd.

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RARECHEM AH CK 0154 N-(2-PHENYLETHYL)PIPERAZINE AKOS BBS-00003639 1-PHENETHYLPIPERAZINE 1-(2-Phenylethyl)piperazine,98+% 1-phenylethylpiperazine 1-(2-Phenylethyl)piperazine 98% PHENETHYLPIPERAZINE 1-(2-PHENYLETHYL)PIPERAZINE DIHYDROCHLORIDE [2-(Piperazin-1-yl)ethyl]benzene N-(beta-Phenylethyl)piperazine N-Phenethylpiperazine 1-(2-Phenylethyl)piperazine CAS 5321-49-3 Piperazine, 1-(2-phenylethyl)- 1-(2-Phenethyl)piperazine 5321-49-3 Building Blocks Heterocyclic Building Blocks Piperazines piperazines 1