5-Bromo-2-methylindole
- CAS No.
- 1075-34-9
- Chemical Name:
- 5-Bromo-2-methylindole
- Synonyms
- 5-Bromo-2-methylindole;2-METHYL-5-BROMO INDOLE;5-BROMO-2-METHYL-1H-INDOLE;1H-Indole, 5-bromo-2-methyl-
- CBNumber:
- CB1705368
- Molecular Formula:
- C9H8BrN
- Molecular Weight:
- 210.07
- MDL Number:
- MFCD01863677
- MOL File:
- 1075-34-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 104-107 °C (lit.) |
|---|---|
| Boiling point | 147-148 °C(Press: 4 Torr) |
| Density | 1.4916 g/cm3 |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | 16.61±0.30(Predicted) |
| form | Powder |
| color | Yellow to pink to tan |
| InChI | 1S/C9H8BrN/c1-6-4-7-5-8(10)2-3-9(7)11-6/h2-5,11H,1H3 |
| InChIKey | BJUZAZKEDCDGRW-UHFFFAOYSA-N |
| SMILES | Cc1cc2cc(Br)ccc2[nH]1 |
| CAS DataBase Reference | 1075-34-9(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2933998090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
5-Bromo-2-methylindole price More Price(68)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 511528 | 5-Bromo-2-methylindole 98% | 1075-34-9 | 5g | $684 | 2026-04-30 | Buy |
| Usbiological | 233973 | 5-Bromo-2-methylindole ≥97% ≥97% | 1075-34-9 | 250mg | $199 | 2026-06-03 | Buy |
| Usbiological | 233973 | 5-Bromo-2-methylindole ≥97% ≥97% | 1075-34-9 | 1g | $240 | 2026-06-03 | Buy |
| Usbiological | 233973 | 5-Bromo-2-methylindole ≥97% ≥97% | 1075-34-9 | 5g | $545 | 2026-06-03 | Buy |
| Usbiological | 233973 | 5-Bromo-2-methylindole ≥97% ≥97% | 1075-34-9 | 25g | $1607 | 2026-06-03 | Buy |
5-Bromo-2-methylindole Chemical Properties, Uses, Production
Uses
5-Bromo-2-methylindole, a bromoalkylindole derivative, has been reported to be prepared by the bromination of 2-methylindole and characterized by 1H NMR.
General Description
5-Bromo-2-methylindole, a bromoalkylindole derivative, has been reported to be prepared by the bromination of 2-methylindole and characterized by 1H NMR.
Synthesis
95-20-5
1075-34-9
Step 1. Synthesis of 5-bromo-2-methyl-7H-indole: To a solution of 2-methyl-1H-indole (5.0 g, 38.12 mmol) in sulfuric acid (80 mL) was added Ag2SO4 (12.5 g, 40.06 mmol) under cooling in an ice bath and stirred for 30 min. Subsequently, Br2 (6.4 g, 40.05 mmol) was slowly added dropwise over 30 minutes. After the dropwise addition, the reaction mixture was continued to be stirred at room temperature for 4 hours. Upon completion of the reaction, the reaction was quenched by the addition of a water/ice mixture (300 mL). The reaction mixture was extracted with dichloromethane (3 x 200 mL), the organic layers were combined, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to afford 5-bromo-2-methyl-7H-indole as a light brown solid (6 g). The product was detected by LC-MS: [M+H]+ m/z 211.0. 1H-NMR (300MHz, CDCl3) δ: 11.23 (s, 1H), 7.56 (s, 1H), 7.21 (d, J=8.7Hz, 1H), 7.07-7.09 (m, 1H), 6.11 (s, 1H), 2.38 (s, 3H).
References
[1] Patent: WO2012/119046, 2012, A2. Location in patent: Page/Page column 161
[2] Patent: US2012/225863, 2012, A1. Location in patent: Page/Page column 28
5-Bromo-2-methylindole Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Gre-syn Chemical Technology Co., Ltd. | 13226079980 | 761330897@qq.com | China | 1160 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Shanghai Sphchem Co., Ltd. | 021-56491756 13512199871 | 2819742715@qq.com | China | 3994 | 55 |
View Latest Price from 5-Bromo-2-methylindole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-24 | 5-BROMO-2-METHYLINDOLE
1075-34-9
|
1KG | 98.0% | 10 | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2019-08-06 | 5-BROMO-2-METHYLINDOLE
1075-34-9
|
$1.00 | 1KG | 95-99% | 100kg/week | Career Henan Chemical Co |
-
- 5-BROMO-2-METHYLINDOLE
1075-34-9
- $0.10
- 98.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- 5-BROMO-2-METHYLINDOLE
1075-34-9
- $1.00
- 95-99%
- Career Henan Chemical Co
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