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Ethyl 3,5-dimethyl-1H-4-pyrazolecarboxylate

Ethyl 3,5-dimethyl-1H-4-pyrazolecarboxylate Structure
Ethyl 3,5-dimethyl-1H-4-pyrazolecarboxylate structure
CAS No.
35691-93-1
Chemical Name:
Ethyl 3,5-dimethyl-1H-4-pyrazolecarboxylate
Synonyms
3,5-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER;3,5-dimethylpyrazole-4-ethyl carboxylate;Ethyl 3,5-Dimethylpyrazole-4-carboxylate;Ethyl 3,5-dimethyl-1H-pyrazol-4-carboxylate;3,5-Dimethyl-4-(ethoxycarbonyl)-1H-pyrazole;Ethyl 3,5-dimethyl-1H-4-pyrazolecarboxylate;ETHYL 3,5-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLATE;ETHYL 3,5-DIMETHYL-1H-PYRRAZOLE-4-CARBOXYLATE;3,5-dimethyl-4-pyrazolecarboxylicaciethylester;3,5-dimethylpyrazole-4-carboxylicacidethylester
CBNumber:
CB1737992
Molecular Formula:
C8H12N2O2
Molecular Weight:
168.19
MDL Number:
MFCD00159638
MOL File:
35691-93-1.mol
MSDS File:
SDS
Last updated:2026-09-12 18:50:04
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Ethyl 3,5-dimethyl-1H-4-pyrazolecarboxylate Properties

Melting point 66 °C
Boiling point 284.8±35.0 °C(Predicted)
Density 1.136±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
form solid
pka 12.82±0.50(Predicted)
Appearance White to off-white Solid
InChI 1S/C8H12N2O2/c1-4-12-8(11)7-5(2)9-10-6(7)3/h4H2,1-3H3,(H,9,10)
InChIKey BCKARVLFIJPHQU-UHFFFAOYSA-N
SMILES CCOC(=O)c1c(C)n[nH]c1C
CAS DataBase Reference 35691-93-1
FDA UNII SS3UNU86DP
UNSPSC Code 12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P260-P271-P280
WGK Germany  WGK 3
HazardClass  IRRITANT
HS Code  2933199090
Storage Class 11 - Combustible Solids
Toxicity LDLo oral in mouse: 250mg/kg
NFPA 704
1
2 0

Ethyl 3,5-dimethyl-1H-4-pyrazolecarboxylate price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth KBA69193 Ethyl 3,5-dimethyl-1H-pyrazole-4-carboxylate 35691-93-1 10g $472 2026-06-04 Buy
Apolloscientific OR9878 Ethyl 3,5-dimethyl-1H-pyrazole-4-carboxylate ≥95% 35691-93-1 1g $21 2026-06-04 Buy
Activate Scientific AS22431-A Ethyl 3,5-Dimethylpyrazole-4-carboxylate 97% 35691-93-1 1g $39 2026-06-04 Buy
Activate Scientific AS22431-A Ethyl 3,5-Dimethylpyrazole-4-carboxylate 97% 35691-93-1 5g $103 2026-06-04 Buy
Activate Scientific AS22431-A Ethyl 3,5-Dimethylpyrazole-4-carboxylate 97% 35691-93-1 25g $468 2026-06-04 Buy
Product number Packaging Price Buy
KBA69193 10g $472 Buy
OR9878 1g $21 Buy
AS22431-A 1g $39 Buy
AS22431-A 5g $103 Buy
AS22431-A 25g $468 Buy

Ethyl 3,5-dimethyl-1H-4-pyrazolecarboxylate Chemical Properties,Uses,Production

Synthesis

Ethyl diacetoacetate

603-69-0

ETHYL 3,5-DIMETHYL-1H-4-PYRAZOLECARBOXYLATE

35691-93-1

General procedure for the synthesis of ethyl 3,5-dimethyl-1H-4-pyrazolecarboxylate from ethyl bisacetoacetate: To a solution of ethyl bisacetoacetate (4.6 g, 26.7 mmol) in ethanol (50 mL) was added hydrazine hydrochloride (1.8 g, 26.7 mmol). The reaction mixture was heated to reflux and kept for 2 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. The resulting residue was washed with ethyl acetate to afford ethyl 3,5-dimethyl-1H-4-pyrazolecarboxylate as a colorless solid (3.1 g, 69% yield), which was pure enough to be used directly in the subsequent reaction.

References

[1] Patent: WO2014/49133, 2014, A1. Location in patent: Page/Page column 44
[2] Justus Liebigs Annalen der Chemie, 1894, vol. 279, p. 237
[3] Archiv der Pharmazie (Weinheim, Germany), 1926, p. 346
[4] Zeitschrift fur Physikalische Chemie, 2013, vol. 227, # 6-7, p. 841 - 856
[5] Journal of Organic Chemistry, 2018, vol. 83, # 12, p. 6454 - 6465

Ethyl 3,5-dimethyl-1H-4-pyrazolecarboxylate Preparation Products And Raw materials

Raw materials

Ethyl diacetoacetate Acethydrazide Ethanol Hydrazine dihydrochloride

Preparation Products

Ethyl 3,5-dimethyl-1H-4-pyrazolecarboxylate Suppliers

Global( 86)Suppliers
Supplier Tel Email Country ProdList Advantage
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd. 21-57721279 18121011378 sales@shydchem.com.cn China 998 56
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Syntechem Co.,Ltd info@syntechem.com China 12973 57
Shanghai civi chemical technology co.,Ltd 86-21-34053660 sale@labgogo.com China 9853 52
Thermo Fisher Scientific 800-810-5118 cnchemical@thermofisher.com China 17752 75
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 22497 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Mashilabs (Shanghai) Co.,Ltd. 19916721580 mafarm@126.com China 4538 58
ShangHai AmK Pharmaceutical Technology Co., Ltd. 微信 18019252918 18019252918 sale@amkchem.com China 14982 55
Supplier Advantage
Wuhan Chemwish Technology Co., Ltd 56
Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd. 56
Shanghai Hanhong Scientific Co.,Ltd. 64
Syntechem Co.,Ltd 57
Shanghai civi chemical technology co.,Ltd 52
Thermo Fisher Scientific 75
9ding chemical ( Shanghai) Limited 55
Bide Pharmatech Ltd. 60
Mashilabs (Shanghai) Co.,Ltd. 58
ShangHai AmK Pharmaceutical Technology Co., Ltd. 55

View Lastest Price from Ethyl 3,5-dimethyl-1H-4-pyrazolecarboxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ETHYL 3,5-DIMETHYL-1H-4-PYRAZOLECARBOXYLATE pictures 2019-12-26 ETHYL 3,5-DIMETHYL-1H-4-PYRAZOLECARBOXYLATE
35691-93-1
 $1.00 1KG 99% 200kg Career Henan Chemical Co

Ethyl 3,5-dimethyl-1H-4-pyrazolecarboxylate Spectrum

ETHYL 3,5-DIMETHYL-1H-4-PYRAZOLECARBOXYLATE(35691-93-1)1HNMR

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3,5-dimethyl-4-pyrazolecarboxylicaciethylester 3,5-dimethylpyrazole-4-carboxylicacidethylester ETHYL 3,5-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLATE ETHYL 3,5-DIMETHYL-1H-PYRRAZOLE-4-CARBOXYLATE Ethyl 3,5-Dimethylpyrazole-4-carboxylate 3,5-Dimethyl-4-(ethoxycarbonyl)-1H-pyrazole 1H-Pyrazole-4-carboxylic acid, 3,5-dimethyl-, ethyl ester Ethyl 3,5-dimethyl-1H-pyrazol-4-carboxylate Ethyl 3,5-dimethyl-1H-pyrazole-4-carboxylate 3,5-dimethylpyrazole-4-ethyl carboxylate 3,5-dimethyl-1H-pyridineazole-4-carboxylic acidethyl ester 3,5-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER Ethyl 3,5-dimethyl-1H-4-pyrazolecarboxylate 35691-93-1