Ethyl 4-(bromomethyl)benzoate
- CAS No.
- 26496-94-6
- Chemical Name:
- Ethyl 4-(bromomethyl)benzoate
- Synonyms
- ETHYL 4-(BROMOMETHYL)BENZOATE;4-ethoxycarbonylbenzyl bromide;4-(methyl bromide) ethyl benzoate;4-(BROMOMETHYL)BENZOIC ACID ETHYL ESTER;Benzoic acid, 4-(bromomethyl)-, ethyl ester;ETHYL (4-BROMOMETHYL) BENZOATE (SB290160007);4-(Bromomethyl)benzoic acid ethyl ester~4-Ethoxycarbonylbenzyl bromide;4-(Ethoxycarbonyl)benzyl bromide, alpha-Bromo-4-(ethoxycarbonyl)toluene
- CBNumber:
- CB1782301
- Molecular Formula:
- C10H11BrO2
- Molecular Weight:
- 243.1
- MDL Number:
- MFCD03791307
- MOL File:
- 26496-94-6.mol
- MSDS File:
- SDS
| Melting point | 40°C |
|---|---|
| Boiling point | 145°C 5mm |
| Density | 1.402±0.06 g/cm3(Predicted) |
| refractive index | 1.5494 |
| Flash point | 145°C/5mm |
| storage temp. | 2-8°C |
| form | fused solid |
| color | White |
| BRN | 1869569 |
| InChI | InChI=1S/C10H11BrO2/c1-2-13-10(12)9-5-3-8(7-11)4-6-9/h3-6H,2,7H2,1H3 |
| InChIKey | TWQLMAJROCNXEA-UHFFFAOYSA-N |
| SMILES | C(OCC)(=O)C1=CC=C(CBr)C=C1 |
| CAS DataBase Reference | 26496-94-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314-H318-H400-H410 | |||||||||
| Precautionary statements | P260h-P301+P330+P331-P303+P361+P353-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 22-34 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | 1759 | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 2916399090 | |||||||||
| Limited Quantities | 1 Kg (2.2 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
Ethyl 4-(bromomethyl)benzoate price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR30551 | Ethyl 4-(bromomethyl)benzoate 98% | 26496-94-6 | 1g | $21 | 2026-06-04 | Buy |
| Activate Scientific | AS214020 | Ethyl 4-(Bromomethyl)benzoate 98% | 26496-94-6 | 5g | $23 | 2026-06-04 | Buy |
| Activate Scientific | AS214020 | Ethyl 4-(Bromomethyl)benzoate 98% | 26496-94-6 | 25g | $57 | 2026-06-04 | Buy |
| Apolloscientific | OR30551 | Ethyl 4-(bromomethyl)benzoate 98% | 26496-94-6 | 500g | $221 | 2026-06-04 | Buy |
| aablocks | AA002TE2 | Ethyl 4-(bromomethyl)benzoate 95% | 26496-94-6 | 5g | $8 | 2026-05-28 | Buy |
Ethyl 4-(bromomethyl)benzoate Chemical Properties, Uses, Production
Uses
4-(bromomethyl)-Benzoic acid ethyl ester is a brominated aromatic building block used in various syntheses such as the preparation of imidazoles and imidazo-fused heterocycles.
Uses
4-(bromomethyl)-Benzoic acid ethyl ester is a brominated aromatic building block used in various syntheses such as the preparation of imidazoles and imidazo-fused heterocycles.
Synthesis
94-08-6
26496-94-6
General procedure for the synthesis of ethyl 4-(bromomethyl)benzoate from ethyl p-methylbenzoate: to a stirred solution of ethyl 4-methylbenzoate (5 g, 30.49 mmol) in carbon tetrachloride (35 ml) was added sequentially N-bromosuccinimide (5.90 g, 33.53 mmol) and benzoyl peroxide (720 mg, 1.52 mmol). The reaction mixture was heated under reflux conditions for 4 h. The progress of the reaction was monitored by thin layer chromatography (TLC). After completion of the reaction, the mixture was cooled to room temperature and subsequently filtered. The filtrate was concentrated by vacuum evaporation to give the colorless oily product ethyl 4-(bromomethyl)benzoate (7.25 g, 98% yield).
References
[1] Chinese Journal of Chemistry, 2012, vol. 30, # 8, p. 1906 - 1908
[2] Patent: WO2009/109999, 2009, A1. Location in patent: Page/Page column 68
[3] Organic Process Research and Development, 1998, vol. 2, # 4, p. 261 - 269
[4] Synthesis (Germany), 2018, vol. 50, # 24, p. 4933 - 4939
[5] Tetrahedron, 2007, vol. 63, # 36, p. 8891 - 8901
Ethyl 4-(bromomethyl)benzoate Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Share Chemical Co., Ltd | 0519-82619998 | wu@sharechem.com | China | 29 | 54 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| XiaoGan ShenYuan ChemPharm co,ltd | 15527621225; 15527621225 | 1791901229@qq.com | China | 6740 | 52 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Shanghai Topbiochem Technology Co., Ltd | +86-21-60341587 | sales@topbiochem.com | China | 6166 | 58 |
| Shanghai Raise Chemical Technology Co.,Ltd | +86-021-50935922 | China | 7854 | 55 | |
| HBCChem, Inc. | +1-510-219-6317 | sales@hbcchem.com | United States | 10628 | 60 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
View Latest Price from Ethyl 4-(bromomethyl)benzoate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | Ethyl 4-(bromomethyl)benzoate
26496-94-6
|
$1.00 | 1kg | 98% | 200kg | Career Henan Chemical Co |
-
- Ethyl 4-(bromomethyl)benzoate
26496-94-6
- $1.00
- 98%
- Career Henan Chemical Co
