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ChemicalBook >> CAS DataBase List >>9H-Purine-2,6-diamine, 9-(1-cyclopropylethyl)-N2-[2-(dimethylamino)ethyl]-N6-[[3-(trifluoromethyl)phenyl]methyl]-

9H-Purine-2,6-diamine, 9-(1-cyclopropylethyl)-N2-[2-(dimethylamino)ethyl]-N6-[[3-(trifluoromethyl)phenyl]methyl]-

9H-Purine-2,6-diamine, 9-(1-cyclopropylethyl)-N2-[2-(dimethylamino)ethyl]-N6-[[3-(trifluoromethyl)phenyl]methyl]- Structure
9H-Purine-2,6-diamine, 9-(1-cyclopropylethyl)-N2-[2-(dimethylamino)ethyl]-N6-[[3-(trifluoromethyl)phenyl]methyl]- structure
CAS No.
2342583-66-6
Chemical Name:
9H-Purine-2,6-diamine, 9-(1-cyclopropylethyl)-N2-[2-(dimethylamino)ethyl]-N6-[[3-(trifluoromethyl)phenyl]methyl]-
Synonyms
NCC007, 10 mM in DMSO;inhibit,NCC-007,Inhibitor,NCC007,NCC 007,Casein Kinase;9-(1-Cyclopropylethyl)-N2-(2-(dimethylamino)ethyl)-N6-(3-(trifluoromethyl)benzyl)-9H-purine-2,6-diamine;9H-Purine-2,6-diamine, 9-(1-cyclopropylethyl)-N2-[2-(dimethylamino)ethyl]-N6-[[3-(trifluoromethyl)phenyl]methyl]-
CBNumber:
CB18245224
Molecular Formula:
C22H28F3N7
Molecular Weight:
447.5
MDL Number:
MFCD32067989
MOL File:
2342583-66-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08
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9H-Purine-2,6-diamine, 9-(1-cyclopropylethyl)-N2-[2-(dimethylamino)ethyl]-N6-[[3-(trifluoromethyl)phenyl]methyl]- Properties

Boiling point 573.5±60.0 °C(Predicted)
Density 1.36±0.1 g/cm3(Predicted)
form Solid
pka 9.02±0.28(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P305+P351+P338

9H-Purine-2,6-diamine, 9-(1-cyclopropylethyl)-N2-[2-(dimethylamino)ethyl]-N6-[[3-(trifluoromethyl)phenyl]methyl]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth STD58366 NCC007 2342583-66-6 250mg $1400 2026-06-05 Buy
ChemScene CS-0097017 NCC007 99.22% 2342583-66-6 5mg $87 2026-06-04 Buy
ChemScene CS-0097017 NCC007 99.22% 2342583-66-6 10mg $130 2026-06-04 Buy
ChemScene CS-0097017 NCC007 99.22% 2342583-66-6 25mg $238 2026-06-04 Buy
ChemScene CS-0097017 NCC007 99.22% 2342583-66-6 50mg $390 2026-06-04 Buy
Product number Packaging Price Buy
STD58366 250mg $1400 Buy
CS-0097017 5mg $87 Buy
CS-0097017 10mg $130 Buy
CS-0097017 25mg $238 Buy
CS-0097017 50mg $390 Buy

9H-Purine-2,6-diamine, 9-(1-cyclopropylethyl)-N2-[2-(dimethylamino)ethyl]-N6-[[3-(trifluoromethyl)phenyl]methyl]- Chemical Properties, Uses, Production

Uses

NCC007 is a dual casein kinase Iα (CKIα) and δ (CKIδ) inhibitor with IC50s of 1.8 and 3.6 μM, respectively. NCC007 can be used in research of modulating mammalian circadian rhythms[1].

Biological Activity

NCC007 is a dual casein kinase Iα (CKIα) and delta (CKIδ) inhibitor with IC50 of 1.8 and 3.6 μM, respectively. It can be used for the study of mammalian circadian rhythms.

in vivo

NCC007 (5-15 mM, infused into the lateral ventricle) controls circadian rhythms through CKI inhibition.

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Animal Model: Adult C57BL/6J background male mice (8 weeks old)
Dosage: 5 , 15 mM
Administration: Infused into the lateral ventricle, constant dark condition
Result: Showed more period lengthening effect with 0.15 hours at 5 mM and 15 mM.

target

CKIα

1.8 μM (IC 50 )

CKIδ

3.6 μM (IC 50 )

IC 50

CKIα: 1.8 μM (IC50); CKIδ: 3.6 μM (IC50)

References

[1] Lee JW, et al. Chemical Control of Mammalian Circadian Behavior through Dual Inhibition of Casein Kinase Iα and δ. J Med Chem. 2019 Feb 28;62(4):1989-1998. DOI:10.1021/acs.jmedchem.8b01541

9H-Purine-2,6-diamine, 9-(1-cyclopropylethyl)-N2-[2-(dimethylamino)ethyl]-N6-[[3-(trifluoromethyl)phenyl]methyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

9H-Purine-2,6-diamine, 9-(1-cyclopropylethyl)-N2-[2-(dimethylamino)ethyl]-N6-[[3-(trifluoromethyl)phenyl]methyl]- Suppliers

Global Suppliers ( 34)
Supplier Tel Email Country ProdList Advantage
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai YuanYe Biotechnology Co., Ltd. 18916372613 yanzihan@shyuanye.com China 87240 60
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
Shanghai Rechem science Co., Ltd. 021-31433387 15618786686 sales@rechemscience.com China 2959 58
Shanghai Chaolan Chemical Technology Center QQ：65489617 13301690235 Sales@ATKchemical.com China 9770 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
InvivoChem +1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6378 58
Zhejiang Huida Biotech Co., LTD 0571-89903022 18679456698 zilong@hizyme.com China 8001 58
cjbscvictory 13348960310 13348960310 3003867561@qq.com China 10233 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
Supplier Advantage
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60
ShangHai Biochempartner Co.,Ltd 62
Shanghai Rechem science Co., Ltd. 58
Shanghai Chaolan Chemical Technology Center 58
TargetMol Chemicals Inc. 58
InvivoChem 58
Zhejiang Huida Biotech Co., LTD 58
cjbscvictory 58
Beijing Jin Ming Biotechnology Co., Ltd. 58

View Latest Price from 9H-Purine-2,6-diamine, 9-(1-cyclopropylethyl)-N2-[2-(dimethylamino)ethyl]-N6-[[3-(trifluoromethyl)phenyl]methyl]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
NCC007 pictures 2026-07-16 NCC007
2342583-66-6
 $41.00-125.00 98.88% 10g TargetMol Chemicals Inc.
  • NCC007 pictures
  • NCC007
    2342583-66-6
  • $41.00-125.00
  • 98.88%
  • TargetMol Chemicals Inc.

2342583-66-6 (9H-Purine-2,6-diamine, 9-(1-cyclopropylethyl)-N2-[2-(dimethylamino)ethyl]-N6-[[3-(trifluoromethyl)phenyl]methyl]-) Related Search:

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9H-Purine-2,6-diamine, 9-(1-cyclopropylethyl)-N2-[2-(dimethylamino)ethyl]-N6-[[3-(trifluoromethyl)phenyl]methyl]- 9-(1-Cyclopropylethyl)-N2-(2-(dimethylamino)ethyl)-N6-(3-(trifluoromethyl)benzyl)-9H-purine-2,6-diamine inhibit,NCC-007,Inhibitor,NCC007,NCC 007,Casein Kinase NCC007, 10 mM in DMSO 2342583-66-6 C22H28F3N7