ChemicalBook >> CAS DataBase List >>1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-6-(1-piperazinyl)-
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-6-(1-piperazinyl)-
- CAS No.
- 2222114-22-7
- Chemical Name:
- 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-6-(1-piperazinyl)-
- Synonyms
- 2-(2,6-dioxopiperidin-3-yl)-5-fluoro-6-(piperazin-1-yl)isoindoline-1,3-dione;Thalidomide-Piperazine 5-fluoride;2-(2,6-Dioxo-3-piperidyl)-5-fluoro-6-(1-piperazinyl)isoindoline-1,3-dione;2-(2,6-Dioxo-3-piperidinyl)-5-fluoro-6-(1-piperazinyl)-1H-isoindole-1,3(2H)-dione;1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-6-(1-piperazinyl)-;2-(2,6-dioxopiperidin-3-yl)-5-fluoro-6-(piperazin-1-yl)-2,3-dihydro-1H-isoindole-1,3-dione;2-(2,6-Dioxopiperidin-3-yl)-5-fluoro-6-(piperazin-1-yl)isoindoline-1,3-dione , Thalidomide-Piperazine 5-fluoride
- CBNumber:
- CB18247233
- Molecular Formula:
- C17H17FN4O4
- Molecular Weight:
- 360.34
- MDL Number:
- MFCD32203463
- MOL File:
- 2222114-22-7.mol
- MSDS File:
- SDS
Last updated:2026-07-16 07:06:08
| Product description | Number | Pack Size | Price |
| Thalidomide-Piperazine 5-fluoride ≥95% | CS-0168629 | 100mg | $73 |
| Thalidomide-Piperazine 5-fluoride ≥95% | CS-0168629 | 250mg | $90 |
| Thalidomide-Piperazine 5-fluoride ≥95% | CS-0168629 | 1g | $228 |
| Thalidomide-Piperazine 5-fluoride ≥95% | CS-0168629 | 5g | $692 |
| Thalidomide-Piperazine 5-fluoride | bp-44945 | 250MG | $120 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362 |
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-6-(1-piperazinyl)- price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0168629 | Thalidomide-Piperazine 5-fluoride ≥95% | 2222114-22-7 | 100mg | $73 | 2026-06-04 | Buy |
| ChemScene | CS-0168629 | Thalidomide-Piperazine 5-fluoride ≥95% | 2222114-22-7 | 250mg | $90 | 2026-06-04 | Buy |
| ChemScene | CS-0168629 | Thalidomide-Piperazine 5-fluoride ≥95% | 2222114-22-7 | 1g | $228 | 2026-06-04 | Buy |
| ChemScene | CS-0168629 | Thalidomide-Piperazine 5-fluoride ≥95% | 2222114-22-7 | 5g | $692 | 2026-06-04 | Buy |
| BroadPharm | bp-44945 | Thalidomide-Piperazine 5-fluoride | 2222114-22-7 | 250MG | $120 | 2026-05-24 | Buy |
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-6-(1-piperazinyl)- Chemical Properties,Uses,Production
Uses
Thalidomide-Piperazine 5-fluoride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
IC 50
Cereblon
References
[1] Hexiang Wang, et al. Degradation of androgen receptor (ar) by conjugation of ar antagonists with e3 ligase ligand and methods of use. WO2021058017A1.
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-6-(1-piperazinyl)- Preparation Products And Raw materials
Raw materials
Preparation Products
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-6-(1-piperazinyl)- Suppliers
Global( 33)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10378 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| Daicel Chiral Technologies (China)CO.,LTD | 021-50460086-9 15921403865 | han_yajun@dctc.daicel.com | China | 6748 | 65 |
| Beijing Yisiyan Technology Research Center | 010-56645598 13366904824; | bjkaida@163.com | China | 1597 | 59 |
| ShangHai Angti Biotechnology Co., Ltd. | 13764913901 | info@angtibio.com | China | 4975 | 55 |
| Shanghai Changyan Chem & Tech Co., Ltd. | 021-20242659 18930833303 | sales@changyanchem.cn | China | 4998 | 55 |
| Shanghai Chaolan Chemical Technology Center | QQ：65489617 13301690235 | Sales@ATKchemical.com | China | 9647 | 58 |
| MQ (shanghai) Pharmaceuticals Co., Ltd. | 13761635123 | sales@linyuepharm.com | China | 5694 | 55 |
| Jiaxing Deyi Chemical Co., Ltd. | 86-0573-85866609 13325730825 | 945717149@qq.com | China | 9241 | 58 |
| Jilin Province Woda Biotechnology Co., Ltd. | 13504435624 | 1927928688@qq.com | China | 1643 | 58 |
View Lastest Price from 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-6-(1-piperazinyl)- manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-15 | Thalidomide-Piperazine 5-fluoride
2222114-22-7
|
10g | TargetMol Chemicals Inc. |
-
- Thalidomide-Piperazine 5-fluoride
2222114-22-7
- $0.00
- TargetMol Chemicals Inc.
2222114-22-7(1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-6-(1-piperazinyl)-)Related Search:
2-(2,6-DIOXOPIPERIDIN-3-YL)-5-FLUORO-6-(PIPERAZIN-1-YL)ISOINDOLINE-1,3-DIONE HCL
2-(2,6-dioxopiperidin-3-yl)-5-(piperazin-1-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-(1-piperazinyl)-, hydrochloride (1:2)
1-Piperazinecarboxylic acid, 4-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-, 1,1-dimethylethyl ester
6-(4-(2-(2,6-Dioxopiperidin-3-yl)-6-fluoro-1,3-dioxoisoindolin-5-yl)piperazin-1-yl)hexanoic acid
1of2
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-6-(1-piperazinyl)-
Thalidomide-Piperazine 5-fluoride
2-(2,6-dioxopiperidin-3-yl)-5-fluoro-6-(piperazin-1-yl)-2,3-dihydro-1H-isoindole-1,3-dione
2-(2,6-Dioxopiperidin-3-yl)-5-fluoro-6-(piperazin-1-yl)isoindoline-1,3-dione , Thalidomide-Piperazine 5-fluoride
2-(2,6-Dioxo-3-piperidyl)-5-fluoro-6-(1-piperazinyl)isoindoline-1,3-dione
2-(2,6-Dioxo-3-piperidinyl)-5-fluoro-6-(1-piperazinyl)-1H-isoindole-1,3(2H)-dione
2-(2,6-dioxopiperidin-3-yl)-5-fluoro-6-(piperazin-1-yl)isoindoline-1,3-dione
2222114-22-7
chem-chemical
