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ChemicalBook >> CAS DataBase List >>3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-[thioxo[[4-(trifluoromethyl)phenyl]amino]methyl]-1-piperazinyl]-

3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-[thioxo[[4-(trifluoromethyl)phenyl]amino]methyl]-1-piperazinyl]-

3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-[thioxo[[4-(trifluoromethyl)phenyl]amino]methyl]-1-piperazinyl]- Structure
3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-[thioxo[[4-(trifluoromethyl)phenyl]amino]methyl]-1-piperazinyl]- structure
CAS No.
1458674-25-3
Chemical Name:
3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-[thioxo[[4-(trifluoromethyl)phenyl]amino]methyl]-1-piperazinyl]-
Synonyms
IMP-1700;1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-[thioxo[[4-(trifluoromethyl)phenyl]amino]methyl]-1-piperazinyl]-3-quinolinecarboxylic acid;3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-[thioxo[[4-(trifluoromethyl)phenyl]amino]methyl]-1-piperazinyl]-
CBNumber:
CB18341063
Molecular Formula:
C25H22F4N4O3S
Molecular Weight:
534.53
MDL Number:
MOL File:
1458674-25-3.mol
MSDS File:
SDS
Last updated:2026-05-11 16:31:51
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3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-[thioxo[[4-(trifluoromethyl)phenyl]amino]methyl]-1-piperazinyl]- Properties

Boiling point 677.3±65.0 °C(Predicted)
Density 1.564±0.06 g/cm3(Predicted)
storage temp. -20°
solubility Soluble in DMSO (up to 25 mg/ml).
pka 6.44±0.41(Predicted)
form solid
color White
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.

3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-[thioxo[[4-(trifluoromethyl)phenyl]amino]methyl]-1-piperazinyl]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML2795 IMP-1700 ≥98% (HPLC) 1458674-25-3 5 mg $91.1 2026-04-30 Buy
Sigma-Aldrich SML2795 IMP-1700 ≥98% (HPLC) 1458674-25-3 25 mg $296 2026-04-30 Buy
Cayman Chemical 33724 IMP-1700 ≥98% 1458674-25-3 5mg $103 2026-04-30 Buy
Cayman Chemical 33724 IMP-1700 ≥98% 1458674-25-3 10mg $173 2026-04-30 Buy
Cayman Chemical 33724 IMP-1700 ≥98% 1458674-25-3 25mg $402 2026-04-30 Buy
Product number Packaging Price Buy
SML2795 5 mg $91.1 Buy
SML2795 25 mg $296 Buy
33724 5mg $103 Buy
33724 10mg $173 Buy
33724 25mg $402 Buy

3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-[thioxo[[4-(trifluoromethyl)phenyl]amino]methyl]-1-piperazinyl]- Chemical Properties, Uses, Production

Description

IMP-1700 (1458674-25-3) is a potent inhibitor of the bacterial DNA double-strand break repair complex AddAB. It is capable of synergistic sensitization of methicillin-resistant staphylococcus aureus (MRSA) to ciprofloxacin (EC50= 0.6nM). IMP-1700 is an important new tool for exploring new treatment options for drug resistant bacteria.

Uses

IMP-1700 is an important tool for exploring new treatment options for drug resistant bacteria. A potent inhibitor of the bacterial DNA double-strand break repair complex AddAB.

References

[1] CARINE S.Q. LIM . Identification of a potent small-molecule inhibitor of bacterial DNA repair that potentiates quinolone antibiotic activity in methicillin-resistant Staphylococcus aureus[J]. Bioorganic & Medicinal Chemistry, 2019, 27 20: Article 114962. DOI:10.1016/j.bmc.2019.06.025

3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-[thioxo[[4-(trifluoromethyl)phenyl]amino]methyl]-1-piperazinyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-[thioxo[[4-(trifluoromethyl)phenyl]amino]methyl]-1-piperazinyl]- Suppliers

Global Suppliers ( 12)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
ChemeGen 18818260767 2625930290@qq.com China 6966 58
Beijing Biocreative Technology Co., Ltd. 15522676233 3007606172@qq.com China 1246 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
Afflon Pharmaceutical (Sichuan) Co., Ltd. 17336178085 1684779048@qq.com China 2263 58
Supplier Advantage
TargetMol Chemicals Inc. 58
ChemeGen 58
Beijing Biocreative Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Afflon Pharmaceutical (Sichuan) Co., Ltd. 58

View Latest Price from 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-[thioxo[[4-(trifluoromethyl)phenyl]amino]methyl]-1-piperazinyl]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
IMP-1700 pictures 2026-05-11 IMP-1700
1458674-25-3
 $337.00-1320.00 10g TargetMol Chemicals Inc.
  • IMP-1700 pictures
  • IMP-1700
    1458674-25-3
  • $337.00-1320.00
  • TargetMol Chemicals Inc.

1458674-25-3 (3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-[thioxo[[4-(trifluoromethyl)phenyl]amino]methyl]-1-piperazinyl]-) Related Search:

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Cyclic di-IMP (sodium salt)

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3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-[thioxo[[4-(trifluoromethyl)phenyl]amino]methyl]-1-piperazinyl]- IMP-1700 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-[thioxo[[4-(trifluoromethyl)phenyl]amino]methyl]-1-piperazinyl]-3-quinolinecarboxylic acid 1458674-25-3 C25H22F4N4O3S