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Fumaryl chloride

CAS No.
627-63-4
Chemical Name:
Fumaryl chloride
Synonyms
trans-2-Butenedioyl dichloride;tl189;TL 189;fumaryl;FumarylChoride;Fumarylchlorid;FUMARYL CHLORIDE;fumaroylchloride;Fumaroyl chloride;FUMARYL DICHLORIDE
CBNumber:
CB1854022
Molecular Formula:
C4H2Cl2O2
Molecular Weight:
152.96
MDL Number:
MFCD00000733
MOL File:
627-63-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:48:28
Product description Number Pack Size Price
Fumaryl chloride 95% 151386 25g $79.9
Fumaryl chloride 95% 151386 5g $26
Fumaryl Chloride >95.0%(GC)(T) F0152 25g $42
Fumaryl Chloride >95.0%(GC)(T) F0152 500g $348
Fumaryl Chloride TRC-F860880-5G 5g $72
More product size

Fumaryl chloride Properties

Melting point -2 °C
Boiling point 161-164 °C(lit.)
Density 1.415 g/mL at 25 °C(lit.)
refractive index n20/D 1.499(lit.)
Flash point 165 °F
storage temp. 2-8°C
form Liquid
Specific Gravity 1.415 (20/4℃)
color Clear yellow
Water Solubility decomposes
Sensitive Moisture Sensitive
BRN 1721342
InChI 1S/C4H2Cl2O2/c5-3(7)1-2-4(6)8/h1-2H/b2-1+
InChIKey ZLYYJUJDFKGVKB-OWOJBTEDSA-N
SMILES ClC(=O)\C=C\C(Cl)=O
CAS DataBase Reference 627-63-4(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII B95L4812RG
NIST Chemistry Reference Fumaryl chloride(627-63-4)
EPA Substance Registry System 2-Butenedioyl dichloride, (2E)- (627-63-4)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)
GHS05,GHS07
Signal word  Danger
Hazard statements  H302+H312-H314-H227-H290
Precautionary statements  P501-P270-P210-P234-P264-P280-P370+P378-P390-P362+P364-P303+P361+P353-P301+P330+P331-P301+P312+P330-P304+P340+P310-P305+P351+P338+P310-P403+P235-P406-P405
PPE Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes  C
Risk Statements  20/21/22-34-37-29-36/37-14
Safety Statements  26-36/37/39-45-8-27
RIDADR  UN 1780
WGK Germany  3
RTECS  LT2800000
21
TSCA  TSCA listed
HazardClass  8
PackingGroup  II
HS Code  29171990
Storage Class 8A - Combustible corrosive hazardous materials
Hazard Classifications Acute Tox. 4 Dermal
Acute Tox. 4 Oral
Skin Corr. 1B
Limited Quantities 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
NFPA 704
2
3 2
W

Fumaryl chloride price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 151386 Fumaryl chloride 95% 627-63-4 25g $79.9 2026-04-30 Buy
Sigma-Aldrich 151386 Fumaryl chloride 95% 627-63-4 5g $26 2022-05-15 Buy
TCI Chemical F0152 Fumaryl Chloride >95.0%(GC)(T) 627-63-4 25g $42 2026-04-30 Buy
TCI Chemical F0152 Fumaryl Chloride >95.0%(GC)(T) 627-63-4 500g $348 2026-04-30 Buy
TRC TRC-F860880-5G Fumaryl Chloride 627-63-4 5g $72 2026-06-03 Buy
Product number Packaging Price Buy
151386 25g $79.9 Buy
151386 5g $26 Buy
F0152 25g $42 Buy
F0152 500g $348 Buy
TRC-F860880-5G 5g $72 Buy

Fumaryl chloride Chemical Properties,Uses,Production

Chemical Properties

Clear yellow liquid

Uses

Chemical intermediate for pharmaceuticals, dyestuffs, and insecticides.

Uses

Fumaryl chloride was used in the preparation of high molecular weight poly(propylene fumarate). The photodissociation dynamics of fumaryl chloride was studied. It is used in agrochemicals and pharmaceuticals manufacturing. Also used as an intermediate for dyes, textile auxiliaries and peroxide compounds. It is an acid halide building block.

Preparation

Fumaryl chloride has been prepared from fumaric acid and phthaloyl chloride, from maleic acid by the action of thionyl chloride in the presence of zinc chloride, and from maleic anhydride by the use of phthaloyl chloride in the presence of zinc chloride.
Org. Synth. 1940, 20, 51
DOI: 10.15227/orgsyn.020.0051

General Description

Fumaryl chloride appears as a straw colored fuming liquid with a pungent odor. Vapors irritate the eyes and mucous membranes. Corrosive to metals and tissue.

Reactivity Profile

Fumaryl chloride is incompatible with strong oxidizing agents, alcohols, amines and other bases. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

Hazard

Corrosive to eyes and skin.

Health Hazard

TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Contact with molten substance may cause severe burns to skin and eyes. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Combustible material: may burn but does not ignite readily. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.

Safety Profile

Moderately toxic by ingestion, inhalation, and skin contact. A skin, eye, and mucous membrane irritant. A corrosive agent. Will react with water or steam to produce toxic and corrosive fumes. When heated to decomposition it emits highly toxic fumes of phosgene and HCl.

Global( 147)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
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CONIER CHEM AND PHARMA LIMITED
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LUYUNJIA CHEMISTRY XIAMEN LIMITED
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Shaanxi Didu New Materials Co. Ltd
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View Lastest Price from Fumaryl chloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Fumaryl chloride pictures 2020-01-03 Fumaryl chloride
627-63-4
$6.60 1KG 97%-99% 1kg -1000kg Career Henan Chemical Co
Dichlorid kyseliny fumarove trans-Butenedioyl chloride FUMAROYL DICHLORIDE FUMARYL CHLORIDE FUMARYL DICHLORIDE Fumarylchloride,95% FumarylChoride 2-Butenedioyl dichloride, (2E)- 2-Butenedioyl dichloride (E)-2-Butenedioyl dichloride (E)-2-Butenedioic acid dichloride Fumaric acid dichloride FuMaryl chloride, 95% 25ML FUMARYL CHLORIDE FOR SYNTHESIS trans-butenedioyl dichloride (2E)-2-Butenedioyl dichloride (E)-1,4-Dioxo-2-butenyldichloride (e)-2-butenedioyldichlorid (E)-butenedioyldichloride 2-Butenedioyl dichloride, (E)- Chlorure de fumaryle chloruredefumaryle dichloridkyselinyfumarove Fumaroyl chloride fumaroylchloride fumaryl Fumarylchlorid TL 189 tl189 FumarylChloride> (E)-But-2-enedioyl dichloride trans-2-Butenedioyl dichloride 627-63-4 C4H2Cl2O2 CHCOC12 ClCOCHCHCOCl Analytical Chromatography Product Catalog Analytical Standards Building Blocks Carbonyl Compounds Organic Building Blocks Acid Halides FM - FZ Alphabetic Acid Halides Carbonyl Compounds Organic Building Blocks