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Taurolithocholic Acid-d5

Taurolithocholic Acid-d5 Structure
Taurolithocholic Acid-d5 structure
CAS No.
2410279-97-7
Chemical Name:
Taurolithocholic Acid-d5
Synonyms
Taurolithocholic acid-d4 sodium;D4-Taurolithocholic Acid Sodium Salt;Taurolithocholic acid, sodium salt (2,2,4,4-D?, 98%);TAUROLITHOCHOLICACID,SODIUMSALT(2,2,4,4-D4) IN METHANOL;Taurolithocholic acid, sodium salt (2,2,4,4-D?, 98%) 100 μg/mL in methanol;Taurolithocholic Acid-[D4] Sodium Salt In Methanol, Concentration: 100μg/mL (Standard);2-[[(3α,5β)-3-hydroxy-24-oxocholan-24-yl-2,2,4,4-d4]amino]-ethanesulfonic acid, monosodium salt
CBNumber:
CB18570997
Molecular Formula:
C26H46NNaO5S
Molecular Weight:
507.71
MDL Number:
MFCD29472019
MOL File:
2410279-97-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:48:20
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Taurolithocholic Acid-d5 Properties

storage temp. -20°C
solubility DMF: 25 mg/ml; DMSO: 20 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 1 mg/ml
form A crystalline solid
UNSPSC Code 12352211
NACRES NA.12
CAS Number Unlabeled 6042-32-6

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Skull and Crossbones (GHS06)Health Hazard (GHS08)
GHS02,GHS06,GHS08
Signal word  Danger
Hazard statements  H225-H301+H311+H331-H370
Precautionary statements  P210-P233-P280-P301+P310-P303+P361+P353-P304+P340+P311
target organs Eyes,Central nervous system
WGK Germany  WGK 2
Storage Class 3 - Flammable liquids
Hazard Classifications Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Flam. Liq. 2
STOT SE 1

Taurolithocholic Acid-d5 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 32984 Taurolithocholic Acid-d4 (sodium salt) ≥99%deuteratedforms(d1-d4) 2410279-97-7 1mg $202 2026-04-30 Buy
Biosynth KWD27997 Taurolithocholic acid-d4 sodium 2410279-97-7 5mg $1237.1 2026-06-04 Buy
Biosynth KWD27997 Taurolithocholic acid-d4 sodium 2410279-97-7 10mg $1721.1 2026-06-04 Buy
Biosynth KWD27997 Taurolithocholic acid-d4 sodium 2410279-97-7 25mg $3227.25 2026-06-04 Buy
Biosynth KWD27997 Taurolithocholic acid-d4 sodium 2410279-97-7 50mg $5163.5 2026-06-04 Buy
Product number Packaging Price Buy
32984 1mg $202 Buy
KWD27997 5mg $1237.1 Buy
KWD27997 10mg $1721.1 Buy
KWD27997 25mg $3227.25 Buy
KWD27997 50mg $5163.5 Buy

Taurolithocholic Acid-d5 Chemical Properties, Uses, Production

Description

Taurolithocholic acid-d4 (TLCA-d4) is intended for use as an internal standard for the quantification of TLCA by GC- or LC-MS. TLCA is a taurine-conjugated form of the secondary bile acid lithocholic acid .1 TLCA (75 μM) increases caspase-3 and -7 activity in Hep3B cells transfected with sodium taurocholate cotransporting peptide (NTCP), but not nontransfected Hep3B cells.2 It has been used to induce cholestasis in ex vivo and in vivo animal models of hepatocellular cholestasis.3,4 Serum levels of TLCA increase approximately 5-fold within two hours during an oral lipid tolerance test in humans.1

Uses

Taurolithocholic acid-d4 (sodium) is the deuterium labeled Taurolithocholic acid (sodium salt). Taurolithocholic acid sodium salt, a potent cholestatic agent, is a potent Ca2+ agonist[1].

References

1. Schmid, A., Neumann, H., Karrasch, T., et al. Bile acid metabolome after an oral lipid tolerance test by liquid chromatography-tandem mass spectrometry (LC-MS/MS) PLoS One 11(2),e0148869(2016).
2. Rust, C., Wild, N., Bernt, C., et al. Bile acid-induced apoptosis in hepatocytes is caspase-6-dependent J. Biol. Chem. 284(5),2908-2916(2009).
3. Denk, G.U., Maitz, S., Wimmer, R., et al. Conjugation is essential for the anticholestatic effect of NorUrsodeoxycholic acid in taurolithocholic acid-induced cholestasis in rat liver Hepatology 52(5),1758-1768(2010).
4. Javitt, N.B. Cholestasis in rats induced by taurolithocholate Nature 210(5042),1262-1263(1966).

Taurolithocholic Acid-d5 Preparation Products And Raw materials

Raw materials

Preparation Products

Taurolithocholic Acid-d5 Suppliers

Global Suppliers ( 15)
Supplier Tel Email Country ProdList Advantage
Artis Biotech Co. Ltd. 18108108965 18108108965 sales@artisbio.com China 2503 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Guangzhou Younan Technology Co., Ltd 020-82000279 18988941452 YN_research@163.com China 2984 58
ChemeGen 18818260767 2625930290@qq.com China 6966 58
Reer Technology (Shanghai) Co., LTD 021-64400900 15800436310 bessey@reertech.com China 4097 58
CHINA ISOTOPE CO., LIMITED 02151600108 13062666369 info@isotopechem.com China 4721 58
SHANGHAI ZZBIO CO., LTD. 18019219489 18901678489 tech@zzbioco.com China 12062 58
ShangHai ZskBio CO., LTD 021-58056897 15399714481 info@zsklab.com China 7539 58
TargetMol 400-821-0310 15002144251 xuexiang.shao@tsbiochem.com China 29128 58
Supplier Advantage
Artis Biotech Co. Ltd. 58
Shanghai EFE Biological Technology Co., Ltd. 58
Guangzhou Younan Technology Co., Ltd 58
ChemeGen 58
Reer Technology (Shanghai) Co., LTD 58
CHINA ISOTOPE CO., LIMITED 58
SHANGHAI ZZBIO CO., LTD. 58
ShangHai ZskBio CO., LTD 58
TargetMol 58

2410279-97-7 (Taurolithocholic Acid-d5) Related Search:

2-[[(3α,5β,7α)-3,7-dihydroxy-24-oxocholan-24-yl-2,2,4,4-d4]amino]-ethanesulfonicacid,monosodiumsalt 2-[[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl-2,2,4,4-d4]amino]-ethanesulfonicacid,monosodiumsalt Tauroursodeoxycholic Acid-d4 (sodium salt) Taurocholic acid-d4 Taurolithocholic-2,2,4,4-D4 Acid
Tauro-α-Muricholic Acid-d4 SodiuM Salt

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2-[[(3α,5β)-3-hydroxy-24-oxocholan-24-yl-2,2,4,4-d4]amino]-ethanesulfonic acid, monosodium salt TAUROLITHOCHOLICACID,SODIUMSALT(2,2,4,4-D4) IN METHANOL Taurolithocholic acid-d4 sodium D4-Taurolithocholic Acid Sodium Salt Taurolithocholic acid, sodium salt (2,2,4,4-D?, 98%) Taurolithocholic acid, sodium salt (2,2,4,4-D?, 98%) 100 μg/mL in methanol Taurolithocholic Acid-[D4] Sodium Salt In Methanol, Concentration: 100μg/mL (Standard) 2410279-97-7