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thiocolchicine

CAS No.
2730-71-4
Chemical Name:
thiocolchicine
Synonyms
NSC 186301;thiocolchicine;thiocholchicine;10-Thiocolchicine;Thiocolchicine, 10 mM in DMSO;Thiocolchicoside EP Impurity B;10-Demethoxy-10-methylthiocolchicine;(S)-7-Acetylamino-6,7-dihydro-10-methylthio-1,2,3-trimethoxybenzo[a]heptalen-9(5H)-one;(S)-7α-Acetylamino-6,7-dihydro-10-(methylthio)-1,2,3-trimethoxybenzo[a]heptalene-9(5H)-one;N-[(S)-5,6,7,9-Tetrahydro-1,2,3-trimethoxy-10-methylthio-9-oxobenzo[a]heptalen-7-yl]acetamide
CBNumber:
CB1926071
Molecular Formula:
C22H25NO5S
Molecular Weight:
415.5
MDL Number:
MFCD01736965
MOL File:
2730-71-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-14 16:49:18

thiocolchicine Properties

Melting point 193℃
Boiling point 729.1±60.0 °C(Predicted)
alpha D20 -221°
Density 1.27±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO: soluble10mg/mL, clear
pka 14.75±0.40(Predicted)
form powder
color white to beige
InChI 1S/C22H25NO5S/c1-12(24)23-16-8-6-13-10-18(26-2)21(27-3)22(28-4)20(13)14-7-9-19(29-5)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1
InChIKey CMEGANPVAXDBPL-INIZCTEOSA-N
SMILES S(C)c1[c](cc2c(cc1)c3c(cc(c(c3OC)OC)OC)CC[C@@H]2NC(=O)C)=O
FDA UNII 47541468FI
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Skull and Crossbones (GHS06)Health Hazard (GHS08)
GHS05,GHS06,GHS08
Signal word  Danger
Hazard statements  H300+H330-H318-H340
Precautionary statements  P201-P280-P301+P310+P330-P304+P340+P310-P305+P351+P338+P310
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26
RIDADR  UN 1544PSN1 6.1 / PGI
WGK Germany  3
Storage Class 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials
Hazard Classifications Acute Tox. 1 Inhalation
Acute Tox. 2 Oral
Eye Dam. 1
Muta. 1B
REACH Registrations Active
NFPA 704
0
4 0

thiocolchicine price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0954 Thiocolchicine ≥97% (HPLC) 2730-71-4 5mg $44.1 2026-04-30 Buy
Sigma-Aldrich SML0954 Thiocolchicine ≥97% (HPLC) 2730-71-4 25mg $180 2026-04-30 Buy
Cayman Chemical 17427 Thiocolchicine ≥98% 2730-71-4 5mg $42 2026-04-30 Buy
Cayman Chemical 17427 Thiocolchicine ≥98% 2730-71-4 10mg $79 2026-04-30 Buy
Cayman Chemical 17427 Thiocolchicine ≥98% 2730-71-4 25mg $183 2026-04-30 Buy
Product number Packaging Price Buy
SML0954 5mg $44.1 Buy
SML0954 25mg $180 Buy
17427 5mg $42 Buy
17427 10mg $79 Buy
17427 25mg $183 Buy

thiocolchicine Chemical Properties, Uses, Production

Chemical Properties

Bright Yellow Solid

Uses

A muscle relaxant.

Biochem/physiol Actions

Thiocolchicine is an antimitotic alkaloid and apoptosis inducer that inhibits tubulin polymerization and microtubule assembly.

64-86-8
5188-07-8
2730-71-4
Synthesis of thiocolchicine from Colchicine and Sodium thiomethoxide

thiocolchicine Preparation Products And Raw materials

Global Suppliers ( 89)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Shanghai Tauto Biotech Co., Ltd. 021-51320588 tauto@tautobiotech.com China 3984 66
Cato Research Chemicals Inc. 020-81960175 min.he@cato-chem.com China 1949 55
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Wuhan ChemFaces Biochemical Co., Ltd. 18607101326 15172504745 aileen@chemfaces.com China 6904 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 sales@rrkchem.com China 57336 58

View Latest Price from thiocolchicine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Thiocolchicine pictures 2026-07-14 Thiocolchicine
2730-71-4
$40.00-129.00 98.19% 10g TargetMol Chemicals Inc.

thiocolchicine Spectrum

2730-71-4 (thiocolchicine) Related Search:

thiocolchicine thiocholchicine (S)-7-Acetylamino-6,7-dihydro-10-methylthio-1,2,3-trimethoxybenzo[a]heptalen-9(5H)-one (S)-7α-Acetylamino-6,7-dihydro-10-(methylthio)-1,2,3-trimethoxybenzo[a]heptalene-9(5H)-one 10-Demethoxy-10-methylthiocolchicine 10-Thiocolchicine N-[(S)-5,6,7,9-Tetrahydro-1,2,3-trimethoxy-10-methylthio-9-oxobenzo[a]heptalen-7-yl]acetamide N-[(7S)-5,6,7,9-Tetrahydro-1,2,3-triMethoxy-10-(Methylthio)-9-oxobenzo[a]heptalen-7-yl]acetaMide NSC 186301 (S)-N-(1,2,3-trimethoxy-10-(methylthio)-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide Thiocolchicoside EP Impurity B Acetamide, N-[(7S)-5,6,7,9-tetrahydro-1,2,3-trimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]- breast,LoVo/DX,MDR-positive,Microtubule/Tubulin,inhibit,MCF-7,leukemia,Colchicine,Apoptosis,BALB/3T3,cancer,A-549,LoVo,Thiocolchicine,Analogue,Inhibitor N-[(7S,12aRa)-1,2,3-trimethoxy-10-(methylsulfanyl)-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide (thiocolchicine) Thiocolchicine, 10 mM in DMSO 2730-71-4 Intermediates & Fine Chemicals Pharmaceuticals