tolycaine
- CAS No.
- 3686-58-6
- Chemical Name:
- tolycaine
- Synonyms
- tolycaine;tolycaine USP/EP/BP;Tolycaine, 10 mM in DMSO;Methyl 2-(2-(diethylaMino)acetaMido)-3-Methylbenzoate;Tolycaine,anesthetic,inhibit,analog,convulsion,Inhibitor;methyl 2-[[2-(diethylamino)acetyl]amino]-3-methylbenzoate;2-[2-(Diethylamino)acetylamino]-m-toluic acid methyl ester;methyl 2-[2-(diethylamino)ethanoylamino]-3-methyl-benzoate;2-[[2-(diethylamino)acetyl]amino]-3-methyl-benzoic acid methyl ester;Benzoic acid, 2-[[(diethylaMino)acetyl]aMino]-3-Methyl-, Methyl ester
- CBNumber:
- CB1931004
- Molecular Formula:
- C15H22N2O3
- Molecular Weight:
- 278.35
- MDL Number:
- MFCD00864442
- MOL File:
- 3686-58-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | <25 °C |
|---|---|
| Boiling point | bp5 190-192° |
| Density | 1.113±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO : ≥ 100 mg/mL (359.26 mM) |
| pka | 13.61±0.70(Predicted) |
| form | Liquid |
| color | Light yellow to yellow |
| FDA UNII | 12R8659YM6 |
tolycaine price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | DAA68658 | Tolycaine | 3686-58-6 | 25mg | $250 | 2026-06-04 | Buy |
| Biosynth | DAA68658 | Tolycaine | 3686-58-6 | 10mg | $250 | 2026-06-04 | Buy |
| Biosynth | DAA68658 | Tolycaine | 3686-58-6 | 50mg | $359.5 | 2026-06-04 | Buy |
| Biosynth | DAA68658 | Tolycaine | 3686-58-6 | 100mg | $576 | 2026-06-04 | Buy |
| Biosynth | DAA68658 | Tolycaine | 3686-58-6 | 250mg | $1080 | 2026-06-04 | Buy |
tolycaine Chemical Properties,Uses,Production
Uses
Tolicaine has anesthetic properties and is used as a local anesthetic.
Originator
Tolycaine Hydrochloride,ZYF Pharm Chemical
Definition
ChEBI: Tolycaine is an amidobenzoic acid.
Manufacturing Process
A suspension of 40 g 2-amino-3-methylbenzoic acid methyl ester in 125 ml of
benzene was added 125 ml of saturated solution of sodium acetate and then
at 0-5°C was added 37 g chloracetylchloride. The mixture was stirred for 1
hour at room temperature. The mixture was filtered. The organic layer was
with 10% solution of potassium carbonate and dries under calcium chloride.
By distillation of the mixture was obtained 15 g of 2-(2-chloroacetylamino)-3-methylbenzoic acid methyl ester; melting point 86-87.5°C (crystallization from
a mixture acetic acid and ligroin); yield 21.8 g.
A mixture of 16 g of 2-(2-chloroacetylamino)-3-methylbenzoic acid methyl
ester and 10 g diethyl amine in benzene was refluxed for 5 hours. After
cooling the diethyl amine hydrochloride was deleted by filtration. The organic
layer was washed with 2 N hydrochloric acid. To the solution was added
potassium carbonate. The product was extracted with ether and distilled.
brand name
Tolycaine Hydrochloride is JAN.
Therapeutic Function
Local anesthetic
tolycaine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
| Shanghai ChuangYan Chemical Technology Co., Ltd. | 021-11111111 11111111111 | 546919421@qq.com | China | 3770 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shanghai hongqu biomedical technology co. LTD | 88888888888 | hongquchem@qq.com | China | 5123 | 58 |
| Zhejiang Huida Biotech Co., LTD | 0571-89903022 18679456698 | zilong@hizyme.com | China | 8001 | 58 |
| Henan Weitesi Chemical Technology Co. LTD | 0371-55135753 18003832934 | 3842570495@qq.com | China | 9989 | 58 |
| Shanghai Sunway Pharmaceutical Technology Co.,Ltd. | 13611835272 13611835272 | mmwang@sunwaypharm.com | China | 44090 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
