SCO-267
- CAS No.
- 1656261-09-4
- Chemical Name:
- SCO-267
- Synonyms
- SCO-267;4-Pyridinepropanoic acid, β-cyclopropyl-2-[[1-[2-[[(2,2-dimethylpropyl)(6-methyl-2-pyridinyl)amino]carbonyl]-5-methoxyphenyl]-4-piperidinyl]methoxy]-, (βS)-
- CBNumber:
- CB19702014
- Molecular Formula:
- C36H46N4O5
- Molecular Weight:
- 614.79
- MDL Number:
- MFCD34474242
- MOL File:
- 1656261-09-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
SCO-267 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | BS179509 | SCO-267 | 1656261-09-4 | 1mg | $199.65 | 2026-06-04 | Buy |
| Biosynth | BS179509 | SCO-267 | 1656261-09-4 | 2mg | $332.76 | 2026-06-04 | Buy |
| Biosynth | BS179509 | SCO-267 | 1656261-09-4 | 5mg | $623.95 | 2026-06-04 | Buy |
| Biosynth | BS179509 | SCO-267 | 1656261-09-4 | 10mg | $1081.5 | 2026-06-04 | Buy |
| Biosynth | BS179509 | SCO-267 | 1656261-09-4 | 25mg | $2162.75 | 2026-06-04 | Buy |
SCO-267 Chemical Properties, Uses, Production
Description
SCO-267 is a novel GPR40 full agonist, improving liver parameters in a mouse model of nonalcoholic fatty liver disease without affecting glucose or body weight.
Uses
SCO-267 is an allosteric GPR40 full agonist. SCO-267 can be used for the research of chronic diseases including diabetes[1].
in vivo
SCO-267 (1 or 10 mg/kg; p.o.) improves insulin sensitivity and exerts sustained glucose-lowering effect[1].
| Animal Model: | N-STZ rats[1] |
| Dosage: | 1 or 10 mg/kg |
| Administration: | P.o.; |
| Result: | Improved insulin sensitivity and exerted sustained glucose-lowering effect. |
References
[1] Koyama R, et al. Chronic Exposure to SCO-267, an Allosteric GPR40 Full Agonist, Is Effective in Improving Glycemic Control in Rats. Mol Pharmacol. 2021 Apr;99(4):286-293. DOI:10.1124/molpharm.120.000168
SCO-267 Preparation Products And Raw materials
Raw materials
Preparation Products
SCO-267 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changsha Fuzhen Biotechnology Co.，LTD | 15111215862 18229892877 | 3062105966@qq.com | China | 5550 | 58 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Changzhou Chenhong Biotechnology Co., Ltd. | +86-0519-85788828 +86-13775037613 | sales@chemrenpharm.com | China | 4058 | 58 |
| Hengyang Jiaxuan Biotechnology Co. LTD | 18684598761 | 675042965@qq.com | China | 308 | 58 |
| Birdo (Shanghai) Medical Technology Co., Ltd. | 021-58099077-8041 18601625411 | sales@birdotech.com | China | 9378 | 58 |
| Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd | 15317229551 | 15151849396@163.com | China | 959 | 58 |
| Taizhou Nanfeng Pharmaceutical Research Institute | nanfengpharma@126.co 18616377689 | nanfengpharma@126.com | China | 20008 | 58 |
| SINO High Goal Chemical Technology Co., Ltd. | 021-57646680 18306277365 | guoxin@chembiobanksh.com | China | 2819 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59929 | 58 |
| Xi'an Kaixin Biotechnology Co., Ltd | 029-68881181 13619217766 | 3495811982@qq.com | China | 2816 | 58 |
