ChemicalBook >> CAS DataBase List >>Mildronate dihydrate
Mildronate dihydrate
- CAS No.
- 86426-17-7
- Chemical Name:
- Mildronate dihydrate
- Synonyms
- Meldonium;Meldonium dihydrate;3-(2,2,2-Trimethylhydrazinium)propionate dihydrate;Mildronate (hydrate);13C,2H3]-Meldonium;Mildronatedehydrate;Miridazine dihydrate;Mildronate dihydrate;Phosphonate dihydrate;Meldonium|||Mildronate
- CBNumber:
- CB21033832
- Molecular Formula:
- C6H14N2O2.2H2O
- Molecular Weight:
- 182.218
- MDL Number:
- MFCD00876389
- MOL File:
- 86426-17-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-08-10 08:01:41
| Melting point | 85 - 87°C |
|---|---|
| storage temp. | 2-8°C |
| solubility | H2O: >40mg/mL |
| form | powder |
| color | white to off-white |
| Water Solubility | H2O: >40mg/mL |
| Stability | Hygroscopic |
| InChI | InChI=1S/C6H14N2O2.2H2O/c1-8(2,3)7-5-4-6(9)10;;/h7H,4-5H2,1-3H3;2*1H2 |
| InChIKey | JFWLFLLRLZSBRA-UHFFFAOYSA-N |
| SMILES | [N+](C)(C)(C)NCCC([O-])=O.O.O |
| FDA UNII | 22DC15W645 |
| ATC code | C01EB22 |
| UNSPSC Code | 41116107 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26 | |||||||||
| WGK Germany | 3 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
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| NFPA 704 |
|
Mildronate dihydrate price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M5199 | Mildronate dihydrate ≥98% (HPLC), powder | 86426-17-7 | 5mg | $128 | 2026-04-30 | Buy |
| Sigma-Aldrich | Y0001670 | Meldonium dihydrate European Pharmacopoeia (EP) Reference Standard | 86426-17-7 | 10 mg | $167 | 2026-04-30 | Buy |
| Sigma-Aldrich | M5199 | Mildronate dihydrate ≥98% (HPLC), powder | 86426-17-7 | 25mg | $428 | 2026-04-30 | Buy |
| Cayman Chemical | 15997 | Mildronate (hydrate) ≥98% | 86426-17-7 | 10mg | $38 | 2026-04-30 | Buy |
| Cayman Chemical | 15997 | Mildronate (hydrate) ≥98% | 86426-17-7 | 25mg | $84 | 2026-04-30 | Buy |
Mildronate dihydrate Chemical Properties, Uses, Production
Appearance
white to off-white powder
Description
Mildronate is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption.Mildronate (40 μM) inhibits the reaction of γ-butyrobetaine hydroxylase with γ-butyrobetaine with Km and Vmax of 36.8 μM and 0.08 nmol/min/mg protein, respectively.
Uses
Meldonium dihydrate has been used as an anti-ischemic agent to evaluate its protective effects on Ischemia-reperfusion (I/R) in chick embryos.
Biochem/physiol Actions
Meldonium is an Inhibitor of γ-butyrobetaine hydroxylase (BBOX) a key enzyme in the synthesis of carnitine.
in vivo
Meldonium (50, 100, or 200 mg/kg; once daily for 3 days) dihydrate modestly attenuates hypoxia-induced lung injury in mice[3].
Mildronate dihydrate Preparation Products And Raw materials
Raw materials
Preparation Products
Global Suppliers ( 133)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong Mingfeng Pharmaceutical and Technology Co. Ltd | 053155551677 15315114555 | 1345456643@qq.com | China | 299 | 58 |
| Jinan Chenghui Shuangda biological Co., LTD | 053158897070 15550412551 | market@jnchsd.com | China | 224 | 62 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4765 | 58 |
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12323 | 58 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| The future of Shanghai Industrial Co., Ltd. | 021-61552785 | sales@shshiji.com | China | 9531 | 55 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4773 | 55 |
| Shanghai JONLN Reagent Co., Ltd. | 400-0066400 13621662912 | 422131432@qq.com | China | 9970 | 55 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
Related articles
- Mildronate Dihydrate: A comprehensive interpretation from crystal structure to dehydration stability
- This article systematically introduces the structural characteristics, application background, preparation methods, detection ....
- Aug 10,2026
View Latest Price from Mildronate dihydrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-18 | Mildronate Dihydrate
86426-17-7
|
1g | More Than 99% | 100kg/Month | BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD. | ||
 |
2026-09-17 | Mildronate dihydrate
86426-17-7
|
1KG | EP, USP | 100ton | Hangzhou Hyper Chemicals Limited | ||
 |
2026-08-08 | Mildronate dihydrate
86426-17-7
|
1kg | 99% | 1T | Shandong Hanjiang Chemical Co., Ltd |
-
- Mildronate Dihydrate
86426-17-7
- $0.00
- More Than 99%
- BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
-
- Mildronate dihydrate
86426-17-7
- EP, USP
- Hangzhou Hyper Chemicals Limited
-
- Mildronate dihydrate
86426-17-7
- 99%
- Shandong Hanjiang Chemical Co., Ltd
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Meldonium dihydrate - Bio-X ?
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Meldonium
Meldonium dihydrate
86426-17-7
C6H14N2O22H2O
Cardiovascular APIs
Inhibitors
86426-17-7
