Carbamic acid, (2,6-dichloro-4-pyridinyl)-, 1,1-dimethylethyl ester (9CI)
- CAS No.
- 501907-61-5
- Chemical Name:
- Carbamic acid, (2,6-dichloro-4-pyridinyl)-, 1,1-dimethylethyl ester (9CI)
- Synonyms
- N-Boc-4-Amino-2,6-dichloropyridine;tert-Butyl (2,6-dichloropyridin-4-yl);t-butyl 2,6-dichloropyridin-4-yl-carbamate;1-N-Boc-4-aMino-2-chloro-3-forMylpyridine ;ert-Butyl(2,6-dichloropyridin-4-yl)carbamate;tert-butyl (2,6-dichloropyridin-4-yl)carbamate;tert-butyl N-(2,6-dichloropyridin-4-yl)carbamate;(2,6-Dichloropyridin-4-yl)carbamic acid tert-butyl ester;(2,6-dichloro-4-pyridinyl)-, 1,1-diMethylethyl ester (9CI);Carbamic acid, N-(2,6-dichloro-4-pyridinyl)-, 1,1-dimethylethyl ester
- CBNumber:
- CB21053924
- Molecular Formula:
- C10H12Cl2N2O2
- Molecular Weight:
- 263.12
- MDL Number:
- MFCD03070211
- MOL File:
- 501907-61-5.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H302-H315-H335 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501 |
Carbamic acid, (2,6-dichloro-4-pyridinyl)-, 1,1-dimethylethyl ester (9CI) price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 118946 | tert-Butyl (2,6-dichloropyridin-4-yl)carbamate | 501907-61-5 | 250.00mg | $180 | 2026-05-18 | Buy |
| Matrix Scientific | 118946 | tert-Butyl (2,6-dichloropyridin-4-yl)carbamate | 501907-61-5 | 1.00g | $450 | 2026-05-18 | Buy |
| Matrix Scientific | 118946 | tert-Butyl (2,6-dichloropyridin-4-yl)carbamate | 501907-61-5 | 5.00g | $1350 | 2026-05-18 | Buy |
| Synthonix | B52701 | tert-Butyl (2,6-dichloropyridin-4-yl)carbamate 95+% | 501907-61-5 | 100mg | $14 | 2026-05-06 | Buy |
| Synthonix | B52701 | tert-Butyl (2,6-dichloropyridin-4-yl)carbamate 95+% | 501907-61-5 | 250mg | $20 | 2026-05-06 | Buy |
Carbamic acid, (2,6-dichloro-4-pyridinyl)-, 1,1-dimethylethyl ester (9CI) Chemical Properties, Uses, Production
Synthesis
2587-02-2
24424-99-5
501907-61-5
Step 1. 4-Amino-2,6-dichloropyridine (5.04 g, 30.3 mmol) was dissolved in dichloromethane (DCM, 100 mL) at room temperature, and 4-dimethylaminopyridine (DMAP, 0.61 g, 4.99 mmol) and di-tert-butyl dicarbonate (Boc2O, 13.71 g, 60.9 mmol) were added sequentially. The reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the organic phase was washed sequentially with saturated aqueous ammonium chloride solution (3 × 30 mL) and brine (40 mL), followed by drying and concentration with anhydrous sodium sulfate. The residue was dissolved in a solvent mixture of tetrahydrofuran (THF, 30 mL) and water (30 mL) and sodium hydroxide (4.5 g, 112 mmol) was added. The reaction mixture was heated at 65 °C for 4 h. After cooling to room temperature, it was extracted with ethyl acetate (EtOAc, 5 × 30 mL). The organic phases were combined and washed sequentially with 1N hydrochloric acid (2 × 30 mL) and water (40 mL), followed by drying and concentration with anhydrous sodium sulfate to give a solid product. The solid was collected by filtration, washed sequentially with 1N hydrochloric acid (4 × 10 mL) and water (20 mL), and finally dried in a vacuum oven at 50 °C to afford N-Boc-4-amino-2,6-dichloropyridine (7.44 g, 93% yield) as a white solid.
References
[1] Patent: WO2015/76800, 2015, A1. Location in patent: Page/Page column 292
[2] Tetrahedron Letters, 2006, vol. 47, # 50, p. 8917 - 8920
[3] Journal of Organic Chemistry, 2008, vol. 73, # 15, p. 6025 - 6028
[4] Patent: WO2016/6974, 2016, A2. Location in patent: Paragraph 516; 517; 518; 519; 520; 521; 522
Carbamic acid, (2,6-dichloro-4-pyridinyl)-, 1,1-dimethylethyl ester (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7881 | 64 |
| Tongchuang Pharma(Suzhou). Co., Ltd. | 0512-63263366 18912765016 | tongtf110@sina.com | China | 984 | 62 |
| Chiba Pharmaceutical Science and technology Co, Ltd. | 0531-81313138 13066006660 | chibapharm@foxmail.com | China | 3996 | 55 |
| Shanghai Topbiochem Technology Co., Ltd | +86-21-60341587 | sales@topbiochem.com | China | 6166 | 58 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Shanghai Witofly Chemical Co.,Ltd | sales@witofly.com | China | 2853 | 52 | |
| Shanghai Raise Chemical Technology Co.,Ltd | 15026594951 | rs@raise-chem.com | China | 4904 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
View Latest Price from Carbamic acid, (2,6-dichloro-4-pyridinyl)-, 1,1-dimethylethyl ester (9CI) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | Carbamic acid, (2,6-dichloro-4-pyridinyl)-, 1,1-dimethylethyl ester (9CI)
501907-61-5
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited |
-
- Carbamic acid, (2,6-dichloro-4-pyridinyl)-, 1,1-dimethylethyl ester (9CI)
501907-61-5
- $1.10
- 99.00%
- Dideu Industries Group Limited
