Ethyl 1,3-dithiolane-2-carboxylate
- CAS No.
- 20461-99-8
- Chemical Name:
- Ethyl 1,3-dithiolane-2-carboxylate
- Synonyms
- 2-Carboethoxydithiolane;2-Carboethoxy-1,3-dithiolane;2-Ethoxycarbonyl-1,3-dithiolane;Ethyl 1,3-Ditholane-2-carboxylate;Ethyl 1,3-dithiolane-2-carboxylate;ETHYL GLYOXYLATE ETHYLENE THIOACETAL;Ethyl 1,3-dithiolane-2-carboxylate,99%;Ethyl 1,3-dithiolane-2-carboxylate, 98+%;Ethyl 1,3-dithiolane-2-carboxylate, GC 99%;Ethyl 1,3-dithiolane-2-carboxylate, 99% 5ML
- CBNumber:
- CB2105967
- Molecular Formula:
- C6H10O2S2
- Molecular Weight:
- 178.27
- MDL Number:
- MFCD00005411
- MOL File:
- 20461-99-8.mol
- TDS File:
- TDS
| Boiling point | 85 °C/0.1 mmHg (lit.) |
|---|---|
| Density | 1.249 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | 2-8°C |
| form | Liquid |
| color | Clear light yellow |
| Specific Gravity | 1.249 |
| BRN | 118157 |
| InChI | 1S/C6H10O2S2/c1-2-8-5(7)6-9-3-4-10-6/h6H,2-4H2,1H3 |
| InChIKey | OMCSHTHLIQOHDD-UHFFFAOYSA-N |
| SMILES | CCOC(=O)C1SCCS1 |
| CAS DataBase Reference | 20461-99-8(CAS DataBase Reference) |
| FDA UNII | ZP3BM93ES6 |
| UNSPSC Code | 12352100 |
Ethyl 1,3-dithiolane-2-carboxylate price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | D2105 | Ethyl 1,3-Dithiolane-2-carboxylate >97.0%(GC) | 20461-99-8 | 5g | $67 | 2024-03-01 | Buy |
| Usbiological | 275988 | Ethyl 1,3-Dithiolane-2-carboxylate Asreported | 20461-99-8 | 2g | $306 | 2026-06-03 | Buy |
| Usbiological | 275988 | Ethyl 1,3-Dithiolane-2-carboxylate Asreported | 20461-99-8 | 5g | $435 | 2026-06-03 | Buy |
| Usbiological | 275988 | Ethyl 1,3-Dithiolane-2-carboxylate Asreported | 20461-99-8 | 10g | $592 | 2026-06-03 | Buy |
| Usbiological | 275988 | Ethyl 1,3-Dithiolane-2-carboxylate Asreported | 20461-99-8 | 25g | $865 | 2026-06-03 | Buy |
Ethyl 1,3-dithiolane-2-carboxylate Chemical Properties, Uses, Production
Chemical Properties
clear light yellow liquid
Uses
Ethyl 1,3-dithiolane-2-carboxylate is an α-keto acid equivalent. It participates in the conjugate additions to enones. It is a bulky equivalent of acetate undergoing syn-selective aldol reactions. Anion derived from ethyl 1,3-dithiolane-2-carboxylate participates as nucleophile during the total synthesis of the corynanthe alkaloid dihydrocorynantheol and the formal syntheses of the indole alkaloids tacamonine, rhynchophylline and hirsutine. It also participates in the conjugate addition of enolates to phenylglycinol-derived α,β-unsaturated δ-lactams.
General Description
Ethyl 1,3-dithiolane-2-carboxylate is an α-keto acid equivalent. It participates in the conjugate additions to enones. It is a bulky equivalent of acetate undergoing syn-selective aldol reactions. Anion derived from ethyl 1,3-dithiolane-2-carboxylate participates as nucleophile during the total synthesis of the corynanthe alkaloid dihydrocorynantheol and the formal syntheses of the indole alkaloids tacamonine, rhynchophylline and hirsutine. It also participates in the conjugate addition of enolates to phenylglycinol-derived α,β-unsaturated δ-lactams.
Purification Methods
Dissolve the ester in CHCl3, wash it with aqueous K2CO3, twice with H2O, dry it over MgSO4, filter, evaporate and distil the residue in vacuo. [Hermann et al Tetrahedron Lett 2599 1973, Corey & Erickson J Org Chem 36 3553 1971]. [Beilstein 19/7 V 225.]
Ethyl 1,3-dithiolane-2-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Beijing Donghualituo Techonlogy Development Co.,Ltd. | 010-88425576 | sales@dhltchem.com | China | 793 | 59 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17752 | 75 |
| Beijing innoChem Science & Technology Co.,Ltd. | 400-810-7969 010-59572699 | ningzi.li@inno-chem.com.cn | China | 6122 | 55 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
View Latest Price from Ethyl 1,3-dithiolane-2-carboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-02-01 | ethyl 1,3-dithiolane-2-carboxylate
20461-99-8
|
$1.00 | 1KG | Min98% HPLC | Career Henan Chemical Co |
-
- ethyl 1,3-dithiolane-2-carboxylate
20461-99-8
- $1.00
- Min98% HPLC
- Career Henan Chemical Co
