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2-AMINO-5-FLUOROBENZOTHIAZOLE

CAS No.
20358-07-0
Chemical Name:
2-AMINO-5-FLUOROBENZOTHIAZOLE
Synonyms
5-FLUOROBENZO[D]THIAZOL-2-AMINE;5-Fluoro-2-benzothiazolamine;2-BenzothiazolaMine,5-fluoro-;2-AMino-5-fluorobenzothiozole;2-AMINO-5-FLUOROBENZOTHIAZOLE;5-Fluoro-2-benzo[d]thiazolamine;2-Amino-5-fluorobenzothiazole>(5-Fluorobenzothiazol-2-yl)amine;5-fluoro-1,3-benzothiazol-2-amine;2-Benzothiazolamine,5-fluoro-(9CI)
CBNumber:
CB2107244
Molecular Formula:
C7H5FN2S
Molecular Weight:
168.19
MDL Number:
MFCD05664560
MOL File:
20358-07-0.mol
Last updated:2025-07-24 18:13:47
Product description Number Pack Size Price
2-Amino-5-fluorobenzothiazole >98.0%(HPLC) A2682 1g $82
2-Amino-5-fluorobenzothiazole >98.0%(HPLC) A2682 5g $247
2-Amino-5-fluorobenzothiazole A576928 50mg $45
2-Amino-5-fluorobenzothiazole FA33580 2g $60
2-Amino-5-fluorobenzothiazole FA33580 5G $125
More product size

2-AMINO-5-FLUOROBENZOTHIAZOLE Properties

Melting point 181°C
Boiling point 312.0±34.0 °C(Predicted)
Density 1.491
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility Soluble in methanol.
pka 3.81±0.10(Predicted)
Appearance Off-white to light brown Solid
CAS DataBase Reference 20358-07-0

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319-H315
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Risk Statements  36/37/38-36/38
Safety Statements  26-36/37/39-28
HS Code  29342000
NFPA 704
0
0 0

2-AMINO-5-FLUOROBENZOTHIAZOLE price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical A2682 2-Amino-5-fluorobenzothiazole >98.0%(HPLC) 20358-07-0 1g $82 2025-07-31 Buy
TCI Chemical A2682 2-Amino-5-fluorobenzothiazole >98.0%(HPLC) 20358-07-0 5g $247 2025-07-31 Buy
TRC A576928 2-Amino-5-fluorobenzothiazole 20358-07-0 50mg $45 2021-12-16 Buy
Biosynth Carbosynth FA33580 2-Amino-5-fluorobenzothiazole 20358-07-0 2g $60 2021-12-16 Buy
Biosynth Carbosynth FA33580 2-Amino-5-fluorobenzothiazole 20358-07-0 5G $125 2021-12-16 Buy
Product number Packaging Price Buy
A2682 1g $82 Buy
A2682 5g $247 Buy
A576928 50mg $45 Buy
FA33580 2g $60 Buy
FA33580 5G $125 Buy

2-AMINO-5-FLUOROBENZOTHIAZOLE Chemical Properties,Uses,Production

Chemical Properties

Powder

Uses

2-Amino-5-fluorobenzothiazole is used as organic chemical synthesis intermediate.

Synthesis

1-(3-FLUOROPHENYL)-2-THIOUREA

458-05-9

2-AMINO-5-FLUOROBENZOTHIAZOLE

20358-07-0

General procedure for the synthesis of 5-fluoro-2-aminobenzothiazole from 1-(3-fluorophenyl)-2-thiourea: 1-(3-fluorophenyl)-2-thiourea (270 mg, 1.59 mmol) was dissolved in dichloromethane (3 mL) at 0 °C. A solution of bromine (279 mg, 1.74 mmol) in dichloromethane (1 mL) was slowly added dropwise for 30 min at 10 °C or lower. Subsequently, the reaction mixture was refluxed for 3 hours. After completion of the reaction, the organic layer was dried with anhydrous magnesium sulfate, filtered and the filtrate was concentrated under reduced pressure. The crude product was purified by column chromatography (eluent: dichloromethane/petroleum ether = 1:1) and dried with anhydrous magnesium sulfate to give the final 5-fluoro-2-aminobenzothiazole (183 mg, 68% yield).

References

[1] Patent: KR101659952, 2016, B1. Location in patent: Paragraph 0247; 0248; 0252
[2] Bioorganic and Medicinal Chemistry, 2006, vol. 14, # 24, p. 8599 - 8607
[3] Journal of the Chemical Society [Section] C: Organic, 1969, p. 268 - 272
[4] Patent: US5356864, 1994, A
[5] Patent: WO2013/163244, 2013, A1. Location in patent: Paragraph 00212

2-AMINO-5-FLUOROBENZOTHIAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-AMINO-5-FLUOROBENZOTHIAZOLE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-AMINO-5-FLUOROBENZOTHIAZOLE pictures 2019-12-25 2-AMINO-5-FLUOROBENZOTHIAZOLE
20358-07-0
US $1.00 / g 1g 99% 1000KGS Career Henan Chemical Co
2-AMINO-5-FLUOROBENZOTHIAZOLE 5-FLUORO-1,3-BENZOTHIAZOL-2-YLAMINE 5-FLUOROBENZO[D]THIAZOL-2-AMINE 2-Benzothiazolamine,5-fluoro-(9CI) 5-fluoro-1,3-benzothiazol-2-amine 2-BenzothiazolaMine,5-fluoro- (5-Fluorobenzothiazol-2-yl)amine 2-AMino-5-fluorobenzothiozole 5-Fluoro-2-benzo[d]thiazolamine 2-Amino-5-fluorobenzothiazole> Cyclopropanamine,1-ethyl-,hydrochloride(1:6) 5-Fluoro-2-benzothiazolamine 20358-07-0 BENZOTHIAZOLE Sulphur Derivatives