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2-Amino-5-fluorobenzothiazole

CAS No.
20358-07-0
Chemical Name:
2-Amino-5-fluorobenzothiazole
Synonyms
5-FLUOROBENZO[D]THIAZOL-2-AMINE;5-Fluoro-2-benzothiazolamine;2-BenzothiazolaMine,5-fluoro-;2-AMino-5-fluorobenzothiozole;2-Amino-5-fluorobenzothiazole;5-Fluoro-2-benzo[d]thiazolamine;2-Amino-5-fluorobenzothiazole>(5-Fluorobenzothiazol-2-yl)amine;5-fluoro-1,3-benzothiazol-2-amine;2-Benzothiazolamine,5-fluoro-(9CI)
CBNumber:
CB2107244
Molecular Formula:
C7H5FN2S
Molecular Weight:
168.19
MDL Number:
MFCD05664560
MOL File:
20358-07-0.mol
MSDS File:
SDS
Last updated:2026-09-12 18:50:09

2-Amino-5-fluorobenzothiazole Properties

Melting point 181°C
Boiling point 312.0±34.0 °C(Predicted)
Density 1.491
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility Soluble in methanol.
pka 3.81±0.10(Predicted)
Appearance Off-white to light brown Solid
CAS DataBase Reference 20358-07-0

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319-H315
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Risk Statements  36/37/38-36/38
Safety Statements  26-36/37/39-28
HS Code  29342000
NFPA 704
0
0 0

2-Amino-5-fluorobenzothiazole price More Price(63)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical A2682 2-Amino-5-fluorobenzothiazole >98.0%(HPLC) 20358-07-0 1g $77 2026-04-30 Buy
TCI Chemical A2682 2-Amino-5-fluorobenzothiazole >98.0%(HPLC) 20358-07-0 5g $231 2026-04-30 Buy
Usbiological 276591 5-Fluorobenzo[d]thiazol-2-amine Asreported 20357-07-0 500mg $439 2026-06-03 Buy
Usbiological 276591 5-Fluorobenzo[d]thiazol-2-amine Asreported 20357-07-0 1g $616 2026-06-03 Buy
Usbiological 276591 5-Fluorobenzo[d]thiazol-2-amine Asreported 20357-07-0 2g $924 2026-06-03 Buy
Product number Packaging Price Buy
A2682 1g $77 Buy
A2682 5g $231 Buy
276591 500mg $439 Buy
276591 1g $616 Buy
276591 2g $924 Buy

2-Amino-5-fluorobenzothiazole Chemical Properties, Uses, Production

Chemical Properties

Powder

Uses

2-Amino-5-fluorobenzothiazole is used as organic chemical synthesis intermediate.

Synthesis

1-(3-FLUOROPHENYL)-2-THIOUREA

458-05-9

2-AMINO-5-FLUOROBENZOTHIAZOLE

20358-07-0

General procedure for the synthesis of 5-fluoro-2-aminobenzothiazole from 1-(3-fluorophenyl)-2-thiourea: 1-(3-fluorophenyl)-2-thiourea (270 mg, 1.59 mmol) was dissolved in dichloromethane (3 mL) at 0 °C. A solution of bromine (279 mg, 1.74 mmol) in dichloromethane (1 mL) was slowly added dropwise for 30 min at 10 °C or lower. Subsequently, the reaction mixture was refluxed for 3 hours. After completion of the reaction, the organic layer was dried with anhydrous magnesium sulfate, filtered and the filtrate was concentrated under reduced pressure. The crude product was purified by column chromatography (eluent: dichloromethane/petroleum ether = 1:1) and dried with anhydrous magnesium sulfate to give the final 5-fluoro-2-aminobenzothiazole (183 mg, 68% yield).

References

[1] Patent: KR101659952, 2016, B1. Location in patent: Paragraph 0247; 0248; 0252
[2] Bioorganic and Medicinal Chemistry, 2006, vol. 14, # 24, p. 8599 - 8607
[3] Journal of the Chemical Society [Section] C: Organic, 1969, p. 268 - 272
[4] Patent: US5356864, 1994, A
[5] Patent: WO2013/163244, 2013, A1. Location in patent: Paragraph 00212

2-Amino-5-fluorobenzothiazole Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 176)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Shanghai Longsheng chemical Co.,Ltd. 58099637 13585536065 sales@shlschem.com China 9880 59
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
China DongFan Chemical Co.,LTD 86-0571-85151182 China 5681 66
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57

View Latest Price from 2-Amino-5-fluorobenzothiazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-AMINO-5-FLUOROBENZOTHIAZOLE pictures 2019-12-25 2-AMINO-5-FLUOROBENZOTHIAZOLE
20358-07-0
$1.00 1g 99% 1000KGS Career Henan Chemical Co
5-FLUORO-1,3-BENZOTHIAZOL-2-YLAMINE 2-Benzothiazolamine,5-fluoro-(9CI) 5-fluoro-1,3-benzothiazol-2-amine 2-BenzothiazolaMine,5-fluoro- (5-Fluorobenzothiazol-2-yl)amine 2-AMino-5-fluorobenzothiozole 5-Fluoro-2-benzo[d]thiazolamine 2-Amino-5-fluorobenzothiazole> Cyclopropanamine,1-ethyl-,hydrochloride(1:6) 5-Fluoro-2-benzothiazolamine 5-FLUOROBENZO[D]THIAZOL-2-AMINE 2-Amino-5-fluorobenzothiazole 20358-07-0 BENZOTHIAZOLE Sulphur Derivatives