2-Amino-5-fluorobenzothiazole
- CAS No.
- 20358-07-0
- Chemical Name:
- 2-Amino-5-fluorobenzothiazole
- Synonyms
- 5-FLUOROBENZO[D]THIAZOL-2-AMINE;5-Fluoro-2-benzothiazolamine;2-BenzothiazolaMine,5-fluoro-;2-AMino-5-fluorobenzothiozole;2-Amino-5-fluorobenzothiazole;5-Fluoro-2-benzo[d]thiazolamine;2-Amino-5-fluorobenzothiazole>(5-Fluorobenzothiazol-2-yl)amine;5-fluoro-1,3-benzothiazol-2-amine;2-Benzothiazolamine,5-fluoro-(9CI)
- CBNumber:
- CB2107244
- Molecular Formula:
- C7H5FN2S
- Molecular Weight:
- 168.19
- MDL Number:
- MFCD05664560
- MOL File:
- 20358-07-0.mol
- MSDS File:
- SDS
| Melting point | 181°C |
|---|---|
| Boiling point | 312.0±34.0 °C(Predicted) |
| Density | 1.491 |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | Soluble in methanol. |
| pka | 3.81±0.10(Predicted) |
| Appearance | Off-white to light brown Solid |
| CAS DataBase Reference | 20358-07-0 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319-H315 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P | |||||||||
| Risk Statements | 36/37/38-36/38 | |||||||||
| Safety Statements | 26-36/37/39-28 | |||||||||
| HS Code | 29342000 | |||||||||
| NFPA 704 |
|
2-Amino-5-fluorobenzothiazole price More Price(63)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | A2682 | 2-Amino-5-fluorobenzothiazole >98.0%(HPLC) | 20358-07-0 | 1g | $77 | 2026-04-30 | Buy |
| TCI Chemical | A2682 | 2-Amino-5-fluorobenzothiazole >98.0%(HPLC) | 20358-07-0 | 5g | $231 | 2026-04-30 | Buy |
| Usbiological | 276591 | 5-Fluorobenzo[d]thiazol-2-amine Asreported | 20357-07-0 | 500mg | $439 | 2026-06-03 | Buy |
| Usbiological | 276591 | 5-Fluorobenzo[d]thiazol-2-amine Asreported | 20357-07-0 | 1g | $616 | 2026-06-03 | Buy |
| Usbiological | 276591 | 5-Fluorobenzo[d]thiazol-2-amine Asreported | 20357-07-0 | 2g | $924 | 2026-06-03 | Buy |
2-Amino-5-fluorobenzothiazole Chemical Properties, Uses, Production
Chemical Properties
Powder
Uses
2-Amino-5-fluorobenzothiazole is used as organic chemical synthesis intermediate.
Synthesis
458-05-9
20358-07-0
General procedure for the synthesis of 5-fluoro-2-aminobenzothiazole from 1-(3-fluorophenyl)-2-thiourea: 1-(3-fluorophenyl)-2-thiourea (270 mg, 1.59 mmol) was dissolved in dichloromethane (3 mL) at 0 °C. A solution of bromine (279 mg, 1.74 mmol) in dichloromethane (1 mL) was slowly added dropwise for 30 min at 10 °C or lower. Subsequently, the reaction mixture was refluxed for 3 hours. After completion of the reaction, the organic layer was dried with anhydrous magnesium sulfate, filtered and the filtrate was concentrated under reduced pressure. The crude product was purified by column chromatography (eluent: dichloromethane/petroleum ether = 1:1) and dried with anhydrous magnesium sulfate to give the final 5-fluoro-2-aminobenzothiazole (183 mg, 68% yield).
References
[1] Patent: KR101659952, 2016, B1. Location in patent: Paragraph 0247; 0248; 0252
[2] Bioorganic and Medicinal Chemistry, 2006, vol. 14, # 24, p. 8599 - 8607
[3] Journal of the Chemical Society [Section] C: Organic, 1969, p. 268 - 272
[4] Patent: US5356864, 1994, A
[5] Patent: WO2013/163244, 2013, A1. Location in patent: Paragraph 00212
2-Amino-5-fluorobenzothiazole Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| China DongFan Chemical Co.,LTD | 86-0571-85151182 | China | 5681 | 66 | |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
View Latest Price from 2-Amino-5-fluorobenzothiazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![]() |
2019-12-25 | 2-AMINO-5-FLUOROBENZOTHIAZOLE
20358-07-0
|
$1.00 | 1g | 99% | 1000KGS | Career Henan Chemical Co |
-

- 2-AMINO-5-FLUOROBENZOTHIAZOLE
20358-07-0
- $1.00
- 99%
- Career Henan Chemical Co
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