2,6-Dimethyl-4-fluorobenzoic acid
- CAS No.
- 16633-50-4
- Chemical Name:
- 2,6-Dimethyl-4-fluorobenzoic acid
- Synonyms
- 4-FLUORO-2,6-DIMETHYLBENZOIC ACID;RARECHEM AL BO 1056;2-Carboxy-5-fluoro-m-xylene;2,6-Dimethyl-4-fluorobenzoic acid;2,6-Dimethyl-4-fluorobenzoicacid97%;Benzoic acid, 4-fluoro-2,6-dimethyl-;4-Fluoro-2,6-dimethyl benzoic acid - [F71840]
- CBNumber:
- CB2111265
- Molecular Formula:
- C9H9FO2
- Molecular Weight:
- 168.16
- MDL Number:
- MFCD06208279
- MOL File:
- Mol file
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xi |
| HS Code | 2916399090 |
2,6-Dimethyl-4-fluorobenzoic acid price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC8961 | 2,6-Dimethyl-4-fluorobenzoic acid ≥95% | 16633-50-4 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | PC8961 | 2,6-Dimethyl-4-fluorobenzoic acid ≥95% | 16633-50-4 | 1g | $56 | 2026-06-04 | Buy |
| Apolloscientific | PC8961 | 2,6-Dimethyl-4-fluorobenzoic acid ≥95% | 16633-50-4 | 5g | $204 | 2026-06-04 | Buy |
| Activate Scientific | AS47474 | 2,6-Dimethyl-4-fluorobenzoic acid 98% | 16633-50-4 | 1g | $99 | 2026-06-04 | Buy |
| Activate Scientific | AS47474 | 2,6-Dimethyl-4-fluorobenzoic acid 98% | 16633-50-4 | 5g | $342 | 2026-06-04 | Buy |
2,6-Dimethyl-4-fluorobenzoic acid Chemical Properties, Uses, Production
Synthesis
14659-60-0
16633-50-4
General procedure for the synthesis of 2,6-dimethyl-4-fluorobenzoic acid from methyl 2,6-dimethyl-4-fluorobenzoate: 4-amino-2,6-dimethylbenzoic acid (200 mg, 1.1 mmol) was heated and reacted with NOBF4 (196 mg, 1.7 mmol) in 1,2-dichlorobenzene at 100 °C for 30 min. Upon completion of the reaction, the reaction solution was cooled to room temperature and subsequently diluted with methanol and water. A few potassium hydroxide pellets (2-3 pellets) were added to the solution and the mixture was heated to reflux for 16 hours. At the end of the reaction, the solution was concentrated. The residue was partitioned between ether and 1N sodium hydroxide solution. The aqueous layer was extracted with ether. The aqueous layer was cooled to 0°C and acidified with concentrated hydrochloric acid to pH=1-2. The acidified aqueous layer was extracted with dichloromethane. The organic layers were combined and dried over anhydrous sodium sulfate. The dried organic layer was filtered and concentrated to give 58 mg (31% yield) of the target product 2,6-dimethyl-4-fluorobenzoic acid as a brown solid.
References
[1] Patent: EP1175401, 2005, B1. Location in patent: Page/Page column 30
[2] Patent: US6391865, 2002, B1. Location in patent: Page column 46
2,6-Dimethyl-4-fluorobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Hunan Hui Bai Shi Biotechnology Co., Ltd. | 0731-85526065 13308475853 | ivy@hnhbsj.com | China | 7236 | 62 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| Shanghai Witofly Chemical Co.,Ltd | sales@witofly.com | China | 2853 | 52 | |
| Shanghai Raise Chemical Technology Co.,Ltd | +86-021-50935922 | China | 7854 | 55 | |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Tianjin Anhao Biological Technology Co., Ltd. | sales@ahpharmatech.com | China | 5734 | 55 | |
| Changzhou Anxuan Chemical, Co., Ltd. | 13912302692 | sales@anxuanchem.com | China | 4824 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
View Latest Price from 2,6-Dimethyl-4-fluorobenzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-02-02 | 2,6-Dimethyl-4-fluorobenzoic acid
16633-50-4
|
5mg | 99%HPLC | 2000tons | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2020-01-13 | 2,6-DIMETHYL-4-FLUOROBENZOIC ACID
16633-50-4
|
$9.80 | 1KG | ≥98% | 20 tons | Career Henan Chemical Co |
-
- 2,6-Dimethyl-4-fluorobenzoic acid
16633-50-4
- 99%HPLC
- Shaanxi Dideu Medichem Co. Ltd
-
- 2,6-DIMETHYL-4-FLUOROBENZOIC ACID
16633-50-4
- $9.80
- ≥98%
- Career Henan Chemical Co
