Utibapril
- CAS No.
- 109683-61-6
- Chemical Name:
- Utibapril
- Synonyms
- Utibapril;FPL-63547;(2S)-5-tert-Butyl-3-[(2S)-2-[[(1S)-1-ethoxycarbonyl-3-phenylpropyl]amino]propanoyl]-2,3-dihydro-1,3,4-thiadiazole-2β-carboxylic acid;1,3,4-Thiadiazole-2-carboxylic acid, 5-(1,1-dimethylethyl)-3-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-2,3-dihydro-, (2S)-
- CBNumber:
- CB21116205
- Molecular Formula:
- C22H31N3O5S
- Molecular Weight:
- 449.57
- MDL Number:
- MFCD00865862
- MOL File:
- 109683-61-6.mol
- MSDS File:
- SDS
| Melting point | 165-168 °C |
|---|---|
| Boiling point | 597.547±60.00 °C(Press: 760.00 Torr)(predicted) |
| Density | 1.246±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| pka | 0.295±0.40(predicted) |
| FDA UNII | 87I5H747BC |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
Utibapril price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | JEA68361 | Utibapril | 109683-61-6 | 1mg | $804.57 | 2026-06-04 | Buy |
| Biosynth | JEA68361 | Utibapril | 109683-61-6 | 5mg | $2273.8 | 2026-06-04 | Buy |
| Biosynth | JEA68361 | Utibapril | 109683-61-6 | 10mg | $3638.1 | 2026-06-04 | Buy |
| Biosynth | JEA68361 | Utibapril | 109683-61-6 | 25mg | $6821.25 | 2026-06-04 | Buy |
| Biosynth | JEA68361 | Utibapril | 109683-61-6 | 50mg | $10914.5 | 2026-06-04 | Buy |
Utibapril Chemical Properties, Uses, Production
Uses
Utibapril is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activities.
in vivo
Utibapril significantly inhibits plasma, renal, and vascular ACE but not ventricular ACE activity. Utibapril (2 μg/kg/day) significantly inhibits vascular ACE activity, and Utibapril (250 μg/kg/day) results in a significant inhibition of plasma ACE. Furthermore, angiotensin I-induced decreases in coronary flow in the isolated heart are significantly inhibited after treatment with the higher doses of utibapril[1]. FPL 63547 is rapidly and extensively excreted as the diacid in the bile but appeared in the urine in negligible amounts[2].
References
[1] Buikema H, et al. Differential inhibition of plasma versus tissue ACE by utibapril: biochemical and functional evidence for inhibition of vascular ACE activity. J Cardiovasc Pharmacol. 1997 May;29(5):684-91. DOI:10.1097/00005344-199705000-00018
[2] Carr RD, et al. Preferential biliary elimination of FPL 63547, a novel inhibitor of angiotensin-converting enzyme, in the rat. Br J Pharmacol. 1990 May;100(1):90-4. DOI:10.1111/j.1476-5381.1990.tb12057.x
Utibapril Preparation Products And Raw materials
Raw materials
Preparation Products
Utibapril Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Regent Biochemical Technology Co., Ltd. | 0755-85201366 18938635012 | sales@regentsciences.com | China | 9377 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9718 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Jinan ponder chemical co. LTD | 0531-0000 | thinklifescience@163.com | China | 19684 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9831 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
View Latest Price from Utibapril manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | Utibapril
109683-61-6
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2026-07-27 | Utibapril
109683-61-6
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2025-07-18 | Utibapril
109683-61-6
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. |
