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(+/-)5-HEPE

CAS No.
83952-40-3
Chemical Name:
(+/-)5-HEPE
Synonyms
(+/-)5-HEPE;FTAGQROYQYQRHF-FCWZHQICSA-N;5-Hydroxy-6(E),8(Z),11(Z),14(Z),17(Z)-EPA;5-hydroxy-6,8,11,14,17-eicosapentaenoic acid;(+/-)5-HYDROXYEICOSA-6E,8Z,11Z,14Z,17Z-PENTAENOIC ACID;(+/-)-5-HYDROXY-6E,8Z,11Z,14Z,17Z-EICOSAPENTAENOIC ACID;6,8,11,14,17-Eicosapentaenoic acid, 5-hydroxy-, (6E,8Z,11Z,14Z,17Z)-
CBNumber:
CB2111674
Molecular Formula:
C20H30O3
Molecular Weight:
318.45
MDL Number:
MFCD00171437
MOL File:
83952-40-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:54:49
Product description Number Pack Size Price
(±)5-HEPE ≥97% 32200 25μg $129
(±)5-HEPE ≥97% 32200 50μg $245
(±)5-HEPE ≥97% 32200 100μg $461
(±)5-HEPE ≥97% 32200 250μg $1025

(+/-)5-HEPE Properties

Boiling point 488.0±45.0 °C(Predicted)
Density 0.997±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml
form Clear to light-yellow liquid.
pka 4.67±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
NFPA 704
3
2 0

(+/-)5-HEPE price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 32200 (±)5-HEPE ≥97% 83952-40-3 25μg $129 2026-04-30 Buy
Cayman Chemical 32200 (±)5-HEPE ≥97% 83952-40-3 50μg $245 2026-04-30 Buy
Cayman Chemical 32200 (±)5-HEPE ≥97% 83952-40-3 100μg $461 2026-04-30 Buy
Cayman Chemical 32200 (±)5-HEPE ≥97% 83952-40-3 250μg $1025 2026-04-30 Buy
Product number Packaging Price Buy
32200 25μg $129 Buy
32200 50μg $245 Buy
32200 100μg $461 Buy
32200 250μg $1025 Buy

(+/-)5-HEPE Chemical Properties,Uses,Production

Description

(±)5-HEPE is produced by non-enzymatic oxidation of EPA. It contains equal amounts of 5(S)-HEPE and 5(R)-HEPE. The biological activity of (±)5-HEPE is likely mediated by one of the individual isomers, most commonly the 5(S) isomer in mammalian systems. EPA can be metabolized to 5-HEPE in human and bovine neutrophils, and human eosinophils, which is further metabolized to 5-oxoEPE and LTB5. The 5-series metabolites of EPA, namely 5-HEPE, 5-oxoEPE, and LTB5, have significantly decreased biological effects compared to the arachidonic acid-derived metabolites.

Uses

(±)5-HEPE is produced by non-enzymatic oxidation of EPA. It contains equal amounts of 5(S)-HEPE and 5(R)-HEPE. The biological activity of (±)5-HEPE is likely mediated by one of the individual isomers, most commonly the 5(S) isomer in mammalian systems. EPA can be metabolized to 5-HEPE in human and bovine neutrophils, and human eosinophils, which is further metabolized to 5-oxoEPE and LTB5. The 5-series metabolites of EPA, namely 5-HEPE, 5-oxoEPE, and LTB5, have significantly decreased biological effects compared to the arachidonic acid-derived metabolites.

Definition

ChEBI: 5-HEPE is a hydroxyicosapentaenoic acid that consists of 6E,8Z,11Z,14Z,17Z-icosapentaenoic acid with the hydroxy group located at position 5. It has a role as a mouse metabolite. It is a conjugate acid of a 5-HEPE(1-).

References

[1] Powell, et al. Formation of a 5-oxo metabolite of 5,8,11,14,17-eicosapentaenoic acid and its effects on human neutrophils and eosinophils. J. Lipid Res. 36, 2590-2598 (1995).

(+/-)5-HEPE Preparation Products And Raw materials

Raw materials

Preparation Products

(+/-)5-HEPE Suppliers

Global( 17)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19935 58
TargetMol Chemicals Inc.
+1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Yichang Zhongyitai Trading Co., Ltd. 0717-6449896 13886658719 root@zhongyitai.com China 1978 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8137 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
SHANGHAI ZZBIO CO., LTD. 18019219489 18901678489 tech@zzbioco.com China 12062 58
Cayman Chemical Company -- sales@caymanchem.com China 6808 58

View Lastest Price from (+/-)5-HEPE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(±)5-HEPE pictures 2026-04-20 (±)5-HEPE
83952-40-3
$1430.00 10g TargetMol Chemicals Inc.
  • (±)5-HEPE pictures
  • (±)5-HEPE
    83952-40-3
  • $1430.00
  • TargetMol Chemicals Inc.
(+/-)5-HEPE (+/-)-5-HYDROXY-6E,8Z,11Z,14Z,17Z-EICOSAPENTAENOIC ACID (+/-)5-HYDROXYEICOSA-6E,8Z,11Z,14Z,17Z-PENTAENOIC ACID 5-hydroxy-6,8,11,14,17-eicosapentaenoic acid FTAGQROYQYQRHF-FCWZHQICSA-N 6,8,11,14,17-Eicosapentaenoic acid, 5-hydroxy-, (6E,8Z,11Z,14Z,17Z)- 5-Hydroxy-6(E),8(Z),11(Z),14(Z),17(Z)-EPA 83952-40-3