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ChemicalBook >> CAS DataBase List >>2,4-Dimethyl-pyrimidine-5-carboxylic acid

2,4-Dimethyl-pyrimidine-5-carboxylic acid

2,4-Dimethyl-pyrimidine-5-carboxylic acid Structure
2,4-Dimethyl-pyrimidine-5-carboxylic acid structure
CAS No.
74356-36-8
Chemical Name:
2,4-Dimethyl-pyrimidine-5-carboxylic acid
Synonyms
ASISCHEM C71549;CHEMBRDG-BB 4019260;TIMTEC-BB SBB010333;ASINEX-REAG BAS 07567148;2,4-dimethylpyrimidine-5-carboxylicaci;2,4-dimethyl-5-pyrimidinecarboxylic acid;2,4-Dimethyl-pyrimidine-5-carboxylic acid;5-Pyrimidinecarboxylic acid, 2,4-dimethyl-;5-Pyrimidinecarboxylicacid,2,4-dimethyl-(6CI,9CI);2,4-dimethylpyrimidine-5-carboxylic acid(SALTDATA: FREE)
CBNumber:
CB2117232
Molecular Formula:
C7H8N2O2
Molecular Weight:
152.15
MDL Number:
MFCD07391755
MOL File:
74356-36-8.mol
MSDS File:
SDS
Last updated:2026-09-12 18:50:12
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2,4-Dimethyl-pyrimidine-5-carboxylic acid Properties

Melting point 154-155 °C(Solv: ethyl acetate (141-78-6))
Boiling point 299.6±20.0 °C(Predicted)
Density 1.257±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 2.62±0.25(Predicted)
Appearance White to yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P305+P351+P338
Hazard Codes  Xi
Risk Statements  36
Safety Statements  26
HazardClass  IRRITANT

2,4-Dimethyl-pyrimidine-5-carboxylic acid price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS26698 2,4-Dimethylpyrimidine-5-carboxylic Acid 95% 74356-36-8 1g $86 2026-06-04 Buy
Activate Scientific AS26698 2,4-Dimethylpyrimidine-5-carboxylic Acid 95% 74356-36-8 5g $303 2026-06-04 Buy
Matrix Scientific 306243 2,4-Dimethyl-pyrimidine-5-carboxylic acid 74356-36-8 250.00mg $63 2026-05-19 Buy
Matrix Scientific 306243 2,4-Dimethyl-pyrimidine-5-carboxylic acid 74356-36-8 1.00g $73 2026-05-19 Buy
Matrix Scientific 306243 2,4-Dimethyl-pyrimidine-5-carboxylic acid 74356-36-8 5.00g $287 2026-05-19 Buy
Product number Packaging Price Buy
AS26698 1g $86 Buy
AS26698 5g $303 Buy
306243 250.00mg $63 Buy
306243 1.00g $73 Buy
306243 5.00g $287 Buy

2,4-Dimethyl-pyrimidine-5-carboxylic acid Chemical Properties, Uses, Production

Synthesis

ETHYL-2,4-DIMETHYL-5-PYRIMIDINE CARBOXYLATE

2226-86-0

2,4-DIMETHYL-PYRIMIDINE-5-CARBOXYLIC ACID

74356-36-8

The general procedure for the synthesis of 2,4-dimethylpyrimidine-5-carboxylic acid from ethyl 2,4-dimethylpyrimidine-5-carboxylate was as follows: potassium hydroxide (67 g, 1.0 mol) was dissolved in 95% ethanol (300 mL), and this solution was then added to a 95% ethanol (100 mL) solution of ethyl 2,4-dimethyl-5-pyrimidinecarboxylate (73 g, 0.40 mol) to the solution. The mixture was heated under reflux conditions for 5 hours. Upon completion of the reaction, the ethanol was removed by evaporation under reduced pressure, the residue was dissolved in water and the aqueous solution was acidified with concentrated hydrochloric acid. The precipitated solid was collected by filtration, washed with water and dried to give 2,4-dimethylpyrimidine-5-carboxylic acid (36 g, 58% yield). The product was characterized by 1H-NMR (CDCl3), δ: 2.63 (3H, s), 2.69 (3H, s), 8.97 (1H, s).

References

[1] Journal of Heterocyclic Chemistry, 1990, vol. 27, # 2, p. 295 - 305
[2] Patent: EP1402900, 2004, A1
[3] Patent: EP1364949, 2003, A1. Location in patent: Page/Page column 100
[4] Chemistry of Heterocyclic Compounds, 2007, vol. 43, # 11, p. 1479 - 1480
[5] Patent: EP2019099, 2009, A1. Location in patent: Page/Page column 15-16

2,4-Dimethyl-pyrimidine-5-carboxylic acid Preparation Products And Raw materials

Raw materials

Ethyl acetoacetate Acetamidine hydrochloride p-Toluenesulfonic acid Toluene Sodium ethoxide
Tetrahydrofuran Ethyl acetate Hydrochloric acid Methanol Sodium hydroxide
N,N-Dimethylformamide dimethyl acetal Magnesium sulfate

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Preparation Products

2,4-Dimethyl-pyrimidine-5-carboxylic acid Suppliers

Global Suppliers ( 84)
Supplier Tel Email Country ProdList Advantage
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Shanghai Ennopharm Co., Ltd. +86 (21) 6435-5022 China 4263 65
EnliPharma Technology Co., Ltd 0551-66399836 18955197623 sales@enlipharma.com China 1875 55
HBCChem, Inc. +1-510-219-6317 sales@hbcchem.com United States 10628 60
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Nantong MYBio-pharm. Co., Ltd. 0513-85921823 18662920231 sales@ntminyanmedical.com China 4561 58
Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 8455 58
Zhengzhou Saifun Biotechnology Co., Ltd. 022-60688926 China 60 55
Shanghai Sainty Biotechnology Co., Ltd. 021-58957915 17721108391 907522080@qq.com China 997 55
Chengdu DingDang Pharmaceutical Co., Ltd. 028-86040038 market@dingdangchem.com China 1853 55
Supplier Advantage
Jia Xing Isenchem Co.,Ltd 66
Shanghai Ennopharm Co., Ltd. 65
EnliPharma Technology Co., Ltd 55
HBCChem, Inc. 60
Bide Pharmatech Ltd. 60
Nantong MYBio-pharm. Co., Ltd. 58
Cool Pharm, Ltd 58
Zhengzhou Saifun Biotechnology Co., Ltd. 55
Shanghai Sainty Biotechnology Co., Ltd. 55
Chengdu DingDang Pharmaceutical Co., Ltd. 55

View Latest Price from 2,4-Dimethyl-pyrimidine-5-carboxylic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,4-DIMETHYL-PYRIMIDINE-5-CARBOXYLIC ACID pictures 2026-08-20 2,4-DIMETHYL-PYRIMIDINE-5-CARBOXYLIC ACID
74356-36-8
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
2,4-dimethylpyrimidine-5-carboxylic acid pictures 2019-07-10 2,4-dimethylpyrimidine-5-carboxylic acid
74356-36-8
 $8.80 1KG 97%-99% 100kg Career Henan Chemical Co

2,4-Dimethyl-pyrimidine-5-carboxylic acid Spectrum

2,4-DIMETHYL-PYRIMIDINE-5-CARBOXYLIC ACID(74356-36-8)1HNMR

74356-36-8 (2,4-Dimethyl-pyrimidine-5-carboxylic acid) Related Search:

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CHEMBRDG-BB 4019260 ASISCHEM C71549 ASINEX-REAG BAS 07567148 5-Pyrimidinecarboxylicacid,2,4-dimethyl-(6CI,9CI) TIMTEC-BB SBB010333 2,4-dimethyl-5-pyrimidinecarboxylic acid 2,4-dimethylpyrimidine-5-carboxylic acid(SALTDATA: FREE) 2,4-dimethylpyrimidine-5-carboxylicaci 2,4-DIMETHYL-PYRIMIDINE-5-CARBOXYLIC ACID ISO 9001：2015 REACH 5-Pyrimidinecarboxylic acid, 2,4-dimethyl- 2,4-Dimethyl-pyrimidine-5-carboxylic acid 74356-36-8 Pyrazines, Pyrimidines & Pyridazines Pyrimidine CARBOXYLICACID pharmacetical Pyrimidine series Carboxylic Acids Pyrazines, Pyrimidines & Pyridazines Carboxylic Acids