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Docarpamine

CAS No.
74639-40-0
Chemical Name:
Docarpamine
Synonyms
TA 870;TA-8704;Tanadopa;Docarpamine;3,4-Bis[(ethoxycarbonyl)oxy]-N-(N-acetyl-L-methionyl)benzeneethanamine;4-{2-[(N-Acetyl-L-methionyl)amino]ethyl}-1,2-phenylenediethylbiscarbonate;(S)-2-(Acetylamino)-N-[3,4-bis(ethoxycarbonyloxy)phenethyl]-4-(methylthio)butanamide;Carbonic acid, 4-[2-[[(2S)-2-(acetylamino)-4-(methylthio)-1-oxobutyl]amino]ethyl]-1,2-phenylene diethyl ester;Carbonic acid, 4-[2-[[2-(acetylamino)-4-(methylthio)-1-oxobutyl]amino]ethyl]-1,2-phenylene diethyl ester, (S)-;Carbonic acid, C,C'-[4-[2-[[2-(acetylamino)-4-(methylthio)-1-oxobutyl]amino]ethyl]-1,2-phenylene] C,C'-diethyl ester
CBNumber:
CB21178560
Molecular Formula:
C21H30N2O8S
Molecular Weight:
470.54
MDL Number:
MFCD00867115
MOL File:
74639-40-0.mol
Last updated:2025-06-30 10:29:57

Docarpamine Properties

Melting point 85-90°; mp 105-108° (Nishiyama, 1992)
alpha D20 -15.6° (c = 2 in methanol)
Boiling point 731.0±60.0 °C(Predicted)
Density 1.222±0.06 g/cm3(Predicted)
pka 14.51±0.46(Predicted)
FDA UNII RPQ57D8S72

SAFETY

Risk and Safety Statements

Toxicity LD50 in male, female rats (mg/kg): 1000-1400, ~1000 s.c.; in rats, dogs (mg/kg): _>2000 orally (Nishiyama, 1992)

Docarpamine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth ZCA63940 Docarpamine 74639-40-0 5mg $1298 2026-06-05 Buy
Biosynth ZCA63940 Docarpamine 74639-40-0 10mg $1947 2026-06-05 Buy
Biosynth ZCA63940 Docarpamine 74639-40-0 25mg $2596 2026-06-05 Buy
Biosynth ZCA63940 Docarpamine 74639-40-0 50mg $3245 2026-06-05 Buy
Biosynth ZCA63940 Docarpamine 74639-40-0 100mg $3894 2026-06-05 Buy
Product number Packaging Price Buy
ZCA63940 5mg $1298 Buy
ZCA63940 10mg $1947 Buy
ZCA63940 25mg $2596 Buy
ZCA63940 50mg $3245 Buy
ZCA63940 100mg $3894 Buy

Docarpamine Chemical Properties, Uses, Production

Description

Docarpamine is a cardiostimulant with diuretic activity launched in Japan for the treatment of circulatory insufficiency. It is an orally effective peripheral dopamine prodrug that is well absorbed from the gastrointestinal tract and converted to dopamine in vivo, which exerts renal vasodilatory and natriuretic effects by activating renal dopamine (DA1) receptors, and a positive inotropic effect by activating cardiac β1-receptors. It has been reported to be effective in treating patients with acute heart failure, shock and acute renal failure.

Originator

Tanabe Seiyaku (Japan)

Uses

Docarpamine maybe a usefule alternative to intravenous dopamine after cardiac surgery.

Definition

ChEBI: Docarpamine is an organic molecular entity.

brand name

Tanadopa

Docarpamine Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 14)
Supplier Tel Email Country ProdList Advantage
SHANGHAI HOHANCE CHEMICAL CO.,LTD 021-31115312 18217084087 mary@hohance.com China 170 62
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
RR Scientific LLC +86-13917743231 sales@rrscientific.com United States 878 58
Hubei Shishun Biotechnology Co. Ltd 027-59223025 15107168801 1718480011@qq.com China 9402 58
Hubei Guangao Biotechnology Co., Ltd 027-02702759223056 18162699093 1208480011@qq.com China 9513 58
Hubei Qifei Pharmaceutical Chemical Co., Ltd 027-59322506 18071128681 1438082200@qq.com China 9554 58
R.R Scientific, LLC. 15010167677 zhiyuu1218@163.com China 876 58
Shaanxi Didu New Material Co., Ltd 81124267 17392282731 1046@dideu.com China 10000 58
Weifu (Shanghai) Pharmaceutical Technology Co., LTD 021-57609736 13917553503 401919639@qq.com China 246 58
TLC Pharmaceutical Standards Ltd. 18012923235 18012923235 chinasales04@tlcstandards.com.cn China 7839 58

View Latest Price from Docarpamine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Docarpamine pictures 2026-06-30 Docarpamine
74639-40-0
1kg 98% 1000kg Shaanxi Dideu New Materials Co. Ltd
  • Docarpamine pictures
  • Docarpamine
    74639-40-0
  • $0.00
  • 98%
  • Shaanxi Dideu New Materials Co. Ltd
Docarpamine Carbonic acid, 4-[2-[[(2S)-2-(acetylamino)-4-(methylthio)-1-oxobutyl]amino]ethyl]-1,2-phenylene diethyl ester Carbonic acid, 4-[2-[[2-(acetylamino)-4-(methylthio)-1-oxobutyl]amino]ethyl]-1,2-phenylene diethyl ester, (S)- TA 870 Tanadopa (S)-2-(Acetylamino)-N-[3,4-bis(ethoxycarbonyloxy)phenethyl]-4-(methylthio)butanamide 3,4-Bis[(ethoxycarbonyl)oxy]-N-(N-acetyl-L-methionyl)benzeneethanamine TA-8704 Carbonic acid, C,C'-[4-[2-[[2-(acetylamino)-4-(methylthio)-1-oxobutyl]amino]ethyl]-1,2-phenylene] C,C'-diethyl ester 4-{2-[(N-Acetyl-L-methionyl)amino]ethyl}-1,2-phenylenediethylbiscarbonate 74639-40-0 C21H30N2O8S