DPPE FUMARATE
- CAS No.
- 1185241-83-1
- Chemical Name:
- DPPE FUMARATE
- Synonyms
- DPPE FUMARATE;Tesmilifene fumarate;DPPE fumarate Tesmilifene;Tesmilifene fumarate, 10 mM in DMSO;N,N-DIETHYL-2-[4-(PHENYLMETHYL)PHENOXY]ETHANAMINE FUMARATE;2-(4-Benzylphenoxy)-N,N-diethylethanamine 2-butenedioate(1:1);inhibit,anti-histaminic,Tesmilifene fumarate,DPPE,Histamine Receptor,seizure,Tesmilifene,chemotherapy,Inhibitor
- CBNumber:
- CB2118466
- Molecular Formula:
- C30H28O4P2
- Molecular Weight:
- 514.49
- MDL Number:
- MFCD09878272
- MOL File:
- Mol file
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| DPPE (fumarate) ≥98% | 35360 | 1mg | $32 |
| DPPE (fumarate) ≥98% | 35360 | 5mg | $109 |
| DPPE (fumarate) ≥98% | 35360 | 10mg | $141 |
| DPPE (fumarate) ≥98% | 35360 | 25mg | $310 |
| DPPEfumarate | 0743 | 10 | $104 |
DPPE FUMARATE price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 35360 | DPPE (fumarate) ≥98% | 1185241-83-1 | 1mg | $32 | 2026-04-30 | Buy |
| Cayman Chemical | 35360 | DPPE (fumarate) ≥98% | 1185241-83-1 | 5mg | $109 | 2026-04-30 | Buy |
| Cayman Chemical | 35360 | DPPE (fumarate) ≥98% | 1185241-83-1 | 10mg | $141 | 2026-04-30 | Buy |
| Cayman Chemical | 35360 | DPPE (fumarate) ≥98% | 1185241-83-1 | 25mg | $310 | 2026-04-30 | Buy |
| Tocris | 0743 | DPPEfumarate | 1185241-83-1 | 10 | $104 | 2021-12-16 | Buy |
DPPE FUMARATE Chemical Properties,Uses,Production
Uses
Tesmilifene fumarate (DPPE fumarate), an H1C receptor antagonist, potentiates a wide range of cytotoxics and even to offer some protection of normal cells[1][2].
Biological Activity
Binds with high affinity to the antiestrogen binding site but not to the estrogen receptor. An inhibitor of histamine binding at the intracellular histamine (H lc ) site.
in vivo
Tesmilifene (DPPE, 20 mg/kg (s.c.) and 20 μg (icv in 5 μL)) potentiated seizures induced by both convulsants[2].
| Animal Model: | Male BKTO mice (25-45 g)[2]. |
| Dosage: | 20 mg/kg (s.c.) and 20 μg (icv in 5 μL). |
| Administration: | S.C. and icv. |
| Result: | Potentiated seizures induced by both convulsants. |
References
[1] Mark Vincent, et al. Tesmilifene may enhance breast cancer chemotherapy by killing a clone of aggressive, multi-drug resistant cells through its action on the p-glycoprotein pump. Med Hypotheses. 2006;66(4):715-31. DOI:10.1016/j.mehy.2005.11.005
[2] G Sturman, et al. Modulation of the intracellular and H3-histamine receptors and chemically-induced seizures in mice Agents Actions. 1994 Jun;41 Spec No:C68-9. DOI:10.1007/BF02007771
DPPE FUMARATE Preparation Products And Raw materials
Raw materials
Preparation Products
DPPE FUMARATE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15838 | 69 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 89689 | 60 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 9697 | 55 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8140 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29757 | 58 |
View Lastest Price from DPPE FUMARATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-22 | Tesmilifene fumarate
1185241-83-1
|
US $39.00-118.00 / mg | 99.86% | 10g | TargetMol Chemicals Inc. |
-
- Tesmilifene fumarate
1185241-83-1
- US $39.00-118.00 / mg
- 99.86%
- TargetMol Chemicals Inc.
