ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE
![ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE Structure](CAS/GIF/64951-04-8.gif)
- CAS No.
- 64951-04-8
- Chemical Name:
- ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE
- Synonyms
- SKL392;ETHYL IMIDAZO[1,2-A]THIAZOLE-6-CARBOXYLATE;Ethyl imidazo[2,1-b]thiazole-6-carboxylate;6-(Ethoxycarbonyl)imidazo[2,1-b][1,3]thiazole;ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE;Ethylimidazo[2,1-b][1,3]thiazole-6-carboxylate97%;Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate 97%;IMIDAZO[2,1-B]THIAZOLE-6-CARBOXYLIC ACID ETHYL ESTER
- CBNumber:
- CB2120201
- Molecular Formula:
- C8H8N2O2S
- Molecular Weight:
- 196.23
- MDL Number:
- MFCD03419464
- MOL File:
- 64951-04-8.mol
| Product description | Number | Pack Size | Price |
| EthylImidazo[2,1-B]thiazole-6-carboxylate | E940308 | 10mg | $45 |
| EthylImidazo[2,1-B]thiazole-6-carboxylate | E940308 | 50mg | $60 |
| Ethyl imidazo[2,1-b]thiazole-6-carboxylate 95+% | 071819 | 5g | $700 |
| Ethyl imidazo[2,1-b]thiazole-6-carboxylate 95+% | 071819 | 10g | $893 |
| Ethylimidazo[2,1-b]thiazole-6-carboxylate | W7636 | 10g | $1255 |
| More product size | |||
| Melting point | 87 °C |
|---|---|
| CAS DataBase Reference | 64951-04-8 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H332-H335 | |||||||||
| Precautionary statements | P261-P280-P305+P351+P338 | |||||||||
| Hazard Note | Harmful | |||||||||
| HS Code | 2934999090 | |||||||||
| NFPA 704 |
|
ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | E940308 | EthylImidazo[2,1-B]thiazole-6-carboxylate | 64951-04-8 | 10mg | $45 | 2021-12-16 | Buy |
| TRC | E940308 | EthylImidazo[2,1-B]thiazole-6-carboxylate | 64951-04-8 | 50mg | $60 | 2021-12-16 | Buy |
| Matrix Scientific | 071819 | Ethyl imidazo[2,1-b]thiazole-6-carboxylate 95+% | 64951-04-8 | 5g | $700 | 2021-12-16 | Buy |
| Matrix Scientific | 071819 | Ethyl imidazo[2,1-b]thiazole-6-carboxylate 95+% | 64951-04-8 | 10g | $893 | 2021-12-16 | Buy |
| AK Scientific | W7636 | Ethylimidazo[2,1-b]thiazole-6-carboxylate | 64951-04-8 | 10g | $1255 | 2021-12-16 | Buy |
ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE Chemical Properties,Uses,Production
Synthesis
96-50-4
70-23-5
![ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE](/CAS/GIF/64951-04-8.gif)
64951-04-8
General procedure for the synthesis of ethylimidazo[2,1-b]thiazole-6-carboxylic acid from 2-aminothiazole (0.500 g, 5 mmol) and ethyl 3-bromopyruvate (90%, 1.625 g, 7.5 mmol): firstly, 2-amino thiazole was dissolved in tetrahydrofuran, followed by the addition of ethyl 3-bromopyruvate dropwise. The reaction mixture was stirred at room temperature for 8 hours before the precipitate was collected by filtration. The resulting filter cake was dissolved in hot ethanol and refluxed at 80°C for 8 hours. After completion of the reaction, the mixture was cooled and the solvent was removed by distillation. The residual solid was washed with cold water and filtered. After drying under vacuum, the intermediate (0.375 g) was obtained, which was dissolved in tetrahydrofuran. The yield of this step was 38.27%.
References
[1] Journal of Medicinal Chemistry, 2003, vol. 46, # 18, p. 3914 - 3929
[2] Journal of Medicinal Chemistry, 2015, vol. 58, # 6, p. 2764 - 2778
[3] Patent: CN105985356, 2016, A. Location in patent: Paragraph 0117; 0118
[4] Farmaco, Edizione Scientifica, 1977, vol. 32, # 10, p. 735 - 746
[5] Patent: US2010/249071, 2010, A1. Location in patent: Page/Page column 45
ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30228 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53803 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532; 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10186 | 62 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17770 | 75 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 17714375163 | cfzhang@aikonchem.com | China | 19906 | 55 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 22514 | 55 |
