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ChemicalBook >> CAS DataBase List >>Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate

Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate

Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate Structure
Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate structure
CAS No.
64951-04-8
Chemical Name:
Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate
Synonyms
SKL392;ETHYL IMIDAZO[1,2-A]THIAZOLE-6-CARBOXYLATE;Ethyl imidazo[2,1-b]thiazole-6-carboxylate;6-(Ethoxycarbonyl)imidazo[2,1-b][1,3]thiazole;Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate;Ethylimidazo[2,1-b][1,3]thiazole-6-carboxylate97%;Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate 97%;IMIDAZO[2,1-B]THIAZOLE-6-CARBOXYLIC ACID ETHYL ESTER
CBNumber:
CB2120201
Molecular Formula:
C8H8N2O2S
Molecular Weight:
196.23
MDL Number:
MFCD03419464
MOL File:
64951-04-8.mol
Last updated:2026-09-12 18:50:12
Request For Quotation

Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate Properties

Melting point 87 °C
CAS DataBase Reference 64951-04-8

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
Hazard Note  Harmful
HS Code  2934999090
NFPA 704
1
2 0

Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR1447 Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate 95% 64951-04-8 1g $141 2026-06-04 Buy
Apolloscientific OR1447 Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate 95% 64951-04-8 5g $483 2026-06-04 Buy
Matrix Scientific 071819 Ethyl imidazo[2,1-b]thiazole-6-carboxylate 64951-04-8 1.00g $231 2026-05-18 Buy
Matrix Scientific 071819 Ethyl imidazo[2,1-b]thiazole-6-carboxylate 64951-04-8 5.00g $700 2026-05-18 Buy
Matrix Scientific 071819 Ethyl imidazo[2,1-b]thiazole-6-carboxylate 64951-04-8 10.00g $893 2026-05-18 Buy
Product number Packaging Price Buy
OR1447 1g $141 Buy
OR1447 5g $483 Buy
071819 1.00g $231 Buy
071819 5.00g $700 Buy
071819 10.00g $893 Buy

Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate Chemical Properties, Uses, Production

Synthesis

2-Aminothiazole

96-50-4

Ethyl bromopyruvate

70-23-5

ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE

64951-04-8

General procedure for the synthesis of ethylimidazo[2,1-b]thiazole-6-carboxylic acid from 2-aminothiazole (0.500 g, 5 mmol) and ethyl 3-bromopyruvate (90%, 1.625 g, 7.5 mmol): firstly, 2-amino thiazole was dissolved in tetrahydrofuran, followed by the addition of ethyl 3-bromopyruvate dropwise. The reaction mixture was stirred at room temperature for 8 hours before the precipitate was collected by filtration. The resulting filter cake was dissolved in hot ethanol and refluxed at 80°C for 8 hours. After completion of the reaction, the mixture was cooled and the solvent was removed by distillation. The residual solid was washed with cold water and filtered. After drying under vacuum, the intermediate (0.375 g) was obtained, which was dissolved in tetrahydrofuran. The yield of this step was 38.27%.

References

[1] Journal of Medicinal Chemistry, 2003, vol. 46, # 18, p. 3914 - 3929
[2] Journal of Medicinal Chemistry, 2015, vol. 58, # 6, p. 2764 - 2778
[3] Patent: CN105985356, 2016, A. Location in patent: Paragraph 0117; 0118
[4] Farmaco, Edizione Scientifica, 1977, vol. 32, # 10, p. 735 - 746
[5] Patent: US2010/249071, 2010, A1. Location in patent: Page/Page column 45

Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate synthesis

96-50-4
70-23-5
64951-04-8
Synthesis of Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate from 2-Aminothiazole and Ethyl bromopyruvate

Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate Preparation Products And Raw materials

Raw materials

2-Aminothiazole Ethyl bromopyruvate

Preparation Products

Imidazo[2,1-b][1,3]thiazole-6-carboxylic acid Imidazo[2,1-b]thiazole-6-carbaldehyde

Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate Suppliers

Global Suppliers ( 54)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Thermo Fisher Scientific 800-810-5118 cnchemical@thermofisher.com China 17752 75
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 22497 55
Shanghai Witofly Chemical Co.,Ltd sales@witofly.com China 2853 52
Shanghai Xingui Biotechnology Co., Ltd. 15121041756 xingui2022@126.com China 9985 58
ShangHai Yuchuan Pharmaceutical Technology Co., Ltd. 02161555100 China 820 58
Shanghai Boyners Pharm-Tech Co., Ltd. 13817873692 mkt@boynerspharm.com China 1707 55
Yancheng Schiemann Biological Technology Co.,Ltd 0515-88280676; 18921872653 sales@ximanbio.com China 1524 56
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Pure Chemistry Scientific Inc. 62
Thermo Fisher Scientific 75
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 55
9ding chemical ( Shanghai) Limited 55
Shanghai Witofly Chemical Co.,Ltd 52
Shanghai Xingui Biotechnology Co., Ltd. 58
ShangHai Yuchuan Pharmaceutical Technology Co., Ltd. 58
Shanghai Boyners Pharm-Tech Co., Ltd. 55
Yancheng Schiemann Biological Technology Co.,Ltd 56

64951-04-8 (Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate) Related Search:

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Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate 97% Ethyl imidazo[2,1-b]thiazole-6-carboxylate IMIDAZO[2,1-B]THIAZOLE-6-CARBOXYLIC ACID ETHYL ESTER ETHYL IMIDAZO[1,2-A]THIAZOLE-6-CARBOXYLATE 6-(Ethoxycarbonyl)imidazo[2,1-b][1,3]thiazole Ethylimidazo[2,1-b][1,3]thiazole-6-carboxylate97% SKL392 Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate 64951-04-8