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ChemicalBook >> CAS DataBase List >>ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE

ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE

ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE Structure
ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE structure
CAS No.
64951-04-8
Chemical Name:
ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE
Synonyms
SKL392;ETHYL IMIDAZO[1,2-A]THIAZOLE-6-CARBOXYLATE;Ethyl imidazo[2,1-b]thiazole-6-carboxylate;6-(Ethoxycarbonyl)imidazo[2,1-b][1,3]thiazole;ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE;Ethylimidazo[2,1-b][1,3]thiazole-6-carboxylate97%;Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate 97%;IMIDAZO[2,1-B]THIAZOLE-6-CARBOXYLIC ACID ETHYL ESTER
CBNumber:
CB2120201
Molecular Formula:
C8H8N2O2S
Molecular Weight:
196.23
MDL Number:
MFCD03419464
MOL File:
64951-04-8.mol
Last updated:2026-05-27 23:54:27
Product description Number Pack Size Price
Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate 95% OR1447 1g $141
Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate 95% OR1447 5g $483
Ethyl imidazo[2,1-b]thiazole-6-carboxylate 071819 1.00g $231
Ethyl imidazo[2,1-b]thiazole-6-carboxylate 071819 5.00g $700
Ethyl imidazo[2,1-b]thiazole-6-carboxylate 071819 10.00g $893
More product size
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ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE Properties

Melting point 87 °C
CAS DataBase Reference 64951-04-8

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
Hazard Note  Harmful
HS Code  2934999090
NFPA 704
1
2 0

ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR1447 Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate 95% 64951-04-8 1g $141 2026-06-04 Buy
Apolloscientific OR1447 Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate 95% 64951-04-8 5g $483 2026-06-04 Buy
Matrix Scientific 071819 Ethyl imidazo[2,1-b]thiazole-6-carboxylate 64951-04-8 1.00g $231 2026-05-18 Buy
Matrix Scientific 071819 Ethyl imidazo[2,1-b]thiazole-6-carboxylate 64951-04-8 5.00g $700 2026-05-18 Buy
Matrix Scientific 071819 Ethyl imidazo[2,1-b]thiazole-6-carboxylate 64951-04-8 10.00g $893 2026-05-18 Buy
Product number Packaging Price Buy
OR1447 1g $141 Buy
OR1447 5g $483 Buy
071819 1.00g $231 Buy
071819 5.00g $700 Buy
071819 10.00g $893 Buy

ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE Chemical Properties,Uses,Production

Synthesis

2-Aminothiazole

96-50-4

Ethyl bromopyruvate

70-23-5

ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE

64951-04-8

General procedure for the synthesis of ethylimidazo[2,1-b]thiazole-6-carboxylic acid from 2-aminothiazole (0.500 g, 5 mmol) and ethyl 3-bromopyruvate (90%, 1.625 g, 7.5 mmol): firstly, 2-amino thiazole was dissolved in tetrahydrofuran, followed by the addition of ethyl 3-bromopyruvate dropwise. The reaction mixture was stirred at room temperature for 8 hours before the precipitate was collected by filtration. The resulting filter cake was dissolved in hot ethanol and refluxed at 80°C for 8 hours. After completion of the reaction, the mixture was cooled and the solvent was removed by distillation. The residual solid was washed with cold water and filtered. After drying under vacuum, the intermediate (0.375 g) was obtained, which was dissolved in tetrahydrofuran. The yield of this step was 38.27%.

References

[1] Journal of Medicinal Chemistry, 2003, vol. 46, # 18, p. 3914 - 3929
[2] Journal of Medicinal Chemistry, 2015, vol. 58, # 6, p. 2764 - 2778
[3] Patent: CN105985356, 2016, A. Location in patent: Paragraph 0117; 0118
[4] Farmaco, Edizione Scientifica, 1977, vol. 32, # 10, p. 735 - 746
[5] Patent: US2010/249071, 2010, A1. Location in patent: Page/Page column 45

ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE synthesis

96-50-4
70-23-5
64951-04-8
Synthesis of ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE from 2-Aminothiazole and Ethyl bromopyruvate

ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE Preparation Products And Raw materials

Raw materials

2-Aminothiazole Ethyl bromopyruvate

Preparation Products

Imidazo[2,1-b][1,3]thiazole-6-carboxylic acid IMIDAZO[2,1-B]THIAZOLE-6-CARBALDEHYDE

ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE Suppliers

Global( 54)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Career Henan Chemica Co 		+86-0371-86658258 +86-13203830695 laboratory@coreychem.com China 30224 58
DAYANG CHEM (HANGZHOU) CO.,LTD 		+86-88938639 +86-17705817739 info@dycnchem.com China 53803 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131956 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10186 62
Thermo Fisher Scientific 800-810-5118 cnchemical@thermofisher.com China 17770 75
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19906 55
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 22514 55
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
Alchem Pharmtech,Inc. 		58
Career Henan Chemica Co 		58
DAYANG CHEM (HANGZHOU) CO.,LTD 		58
Amadis Chemical Company Limited 		58
J & K SCIENTIFIC LTD. 76
Pure Chemistry Scientific Inc. 62
Thermo Fisher Scientific 75
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 55
9ding chemical ( Shanghai) Limited 55

64951-04-8(ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE)Related Search:

IMIDAZO[2,1-B]THIAZOLE-6-CARBALDEHYDE 4-ETHOXYCARBONYLIMIDAZOLE-2-THIOL (2-MERCAPTO-1-METHYL-1H-IMIDAZOL-5-YL)METHANOL ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE 3-METHYLIMIDAZO[2,1-B]THIAZOLE-6-CARBOXYLIC ACID ETHYL ESTER
IMIDAZO[2,1-B]THIAZOL-6-YLMETHANOL Imidazo[2,1-b][1,3]thiazole-6-carboxylic acid

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Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate 97% Ethyl imidazo[2,1-b]thiazole-6-carboxylate IMIDAZO[2,1-B]THIAZOLE-6-CARBOXYLIC ACID ETHYL ESTER ETHYL IMIDAZO[1,2-A]THIAZOLE-6-CARBOXYLATE ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE 6-(Ethoxycarbonyl)imidazo[2,1-b][1,3]thiazole Ethylimidazo[2,1-b][1,3]thiazole-6-carboxylate97% SKL392 64951-04-8