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Deoxynojirimycin hydrochloride

Deoxynojirimycin hydrochloride Structure
Deoxynojirimycin hydrochloride structure
CAS No.
73285-50-4
Chemical Name:
Deoxynojirimycin hydrochloride
Synonyms
DNJ;DEOXYNOJIRIMYCIN;1-DNJ;DNM;DNM1;AT 2220;DNJ, HCL;B-dynamin;DEOXYNOJIRIMICIN;Dynamin BREDNM19
CBNumber:
CB2128151
Molecular Formula:
C6H13NO4.ClH
Molecular Weight:
199.63
MDL Number:
MFCD00083611
MOL File:
73285-50-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-08-28 18:22:08
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Deoxynojirimycin hydrochloride Properties

Melting point 195-196°C
storage temp. Inert atmosphere,2-8°C
solubility Water (Slightly)
form Powder
color White
Water Solubility Soluble in water at 20mg/ml
BRN 3563225
Stability Hygroscopic
InChI InChI=1/C6H13NO4.ClH/c8-2-3-5(10)6(11)4(9)1-7-3;/h3-11H,1-2H2;1H/t3-,4+,5-,6-;/s3
InChIKey ZJIHMALTJRDNQI-KOVNLEGCNA-N
SMILES C([C@H]1NC[C@@H]([C@H]([C@@H]1O)O)O)O.Cl |&1:1,4,5,6,r|
CAS DataBase Reference 73285-50-4
FDA UNII 0RN23C42QR
UNSPSC Code 12352200

SAFETY

Risk and Safety Statements

Hazard Codes  Xi
Risk Statements  36/38
Safety Statements  26-36-24/25-22
WGK Germany  3
F  10
Storage Class 11 - Combustible Solids

Deoxynojirimycin hydrochloride price More Price(59)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D9305 1-Deoxynojirimycin hydrochloride 73285-50-4 5mg $278 2026-04-30 Buy
Cayman Chemical 10011718 1-Deoxynojirimycin (hydrochloride) ≥95% 73285-50-4 5mg $37 2026-04-30 Buy
Cayman Chemical 10011718 1-Deoxynojirimycin (hydrochloride) ≥95% 73285-50-4 10mg $62 2026-04-30 Buy
Cayman Chemical 10011718 1-Deoxynojirimycin (hydrochloride) ≥95% 73285-50-4 25mg $132 2026-04-30 Buy
Cayman Chemical 10011718 1-Deoxynojirimycin (hydrochloride) ≥95% 73285-50-4 50mg $194 2026-04-30 Buy
Product number Packaging Price Buy
D9305 5mg $278 Buy
10011718 5mg $37 Buy
10011718 10mg $62 Buy
10011718 25mg $132 Buy
10011718 50mg $194 Buy

Deoxynojirimycin hydrochloride Chemical Properties, Uses, Production

Description

1-Deoxynojirimycin (1-DNJ) is an iminosugar that has been found in M. alba (mulberry) leaves and has diverse biological activities. It inhibits the activities of α- and β-glucosidase (IC50s = 35 and 71 μM, respectively). 1-DNJ (5 mM) reduces the formation of N-linked complex oligosaccharides in IEC-6 cells. It inhibits HIV-1 envelope-mediated membrane fusion in CEM cells when used at a concentration of 2 mM. 1-DNJ (1-100 μg/ml) reduces the invasion and migration of B16/F10 mouse melanoma cells. It improves glucose and insulin tolerance in db/db mice when administered intravenously at doses ranging from 20 to 80 mg/kg per day for four weeks.

Chemical Properties

White Crystalline Solid

Uses

natural chitin synthase inhibitor

General Description

Specific glucosidase inhibitor, including trimming glucosidases I and II, that sequentially removes the three glucose residues from precursor Glc3Man9GlcNAc2 in N-linked glycan biosynthesis.

Biochem/physiol Actions

Product does not compete with ATP.

References

[1] KUO GAO. 1-Deoxynojirimycin: Occurrence, Extraction, Chemistry, Oral Pharmacokinetics, Biological Activities and In Silico Target Fishing.[J]. Molecules, 2016, 21 1. DOI: 10.3390/molecules21111600
[2] ANA I AHUJA-CASARíN. Tuning the activity of iminosugars: novel N-alkylated deoxynojirimycin derivatives as strong BuChE inhibitors.[J]. Journal of Enzyme Inhibition and Medicinal Chemistry, 2021: 138-146. DOI: 10.1080/14756366.2020.1847101
[3] JULIAN A. CODELLI. Second-Generation Difluorinated Cyclooctynes for Copper-Free Click Chemistry[J]. Journal of the American Chemical Society, 2008, 130 34: 11486-11493. DOI: 10.1021/ja803086r
[4] MARIE-JEANNE PAPANDRéOU. The alpha-glucosidase inhibitor 1-deoxynojirimycin blocks human immunodeficiency virus envelope glycoprotein-mediated membrane fusion at the CXCR4 binding step.[J]. Molecular Pharmacology, 2002, 61 1 1: 186-193. DOI: 10.1124/mol.61.1.186
[5] RAN-JUH WANG  Miao L H  Chun Hung Yang. 1-Deoxynojirimycin Inhibits Metastasis of B16F10 Melanoma Cells by Attenuating the Activity and Expression of Matrix Metalloproteinases-2 and -9 and Altering Cell Surface Glycosylation[J]. Journal of Agricultural and Food Chemistry, 2010, 58 16: 8988-8993. DOI: 10.1021/jf101401b
[6] QINGPU LIU. 1-Deoxynojirimycin Alleviates Insulin Resistance via Activation of Insulin Signaling PI3K/AKT Pathway in Skeletal Muscle of db/db Mice.[J]. Molecules, 2015, 20 1: 21700-21714. DOI: 10.3390/molecules201219794

Deoxynojirimycin hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Deoxynojirimycin hydrochloride Suppliers

Global Suppliers ( 199)
Supplier Tel Email Country ProdList Advantage
Suzhou Sanyi Polymer Chemical Technology Co., Ltd. 13951113810 170354953@qq.com China 127 58
Anhui Yongsheng Pharmaceutical Technology Co., Ltd 3307 18017383231 983544897@qq.com China 941 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Syntechem Co.,Ltd info@syntechem.com China 12973 57
Hunan Hui Bai Shi Biotechnology Co., Ltd. 0731-85526065 13308475853 ivy@hnhbsj.com China 7236 62
ShangHai YuanYe Biotechnology Co., Ltd. 15026964105 shyysw007@163.com China 4998 60
Chengdu Forest Science and Technology Development Co., Ltd. 18030648795 18030648795 sales@cdforestchem.com China 1998 58
Shanghai Ruji Biology Technology Co., Ltd. +86-21-65211385-8001 36031160 sales@shruji.com China 3223 55
Supplier Advantage
Suzhou Sanyi Polymer Chemical Technology Co., Ltd. 58
Anhui Yongsheng Pharmaceutical Technology Co., Ltd 58
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Chemsky（shanghai）International Co.,Ltd. 50
Syntechem Co.,Ltd 57
Hunan Hui Bai Shi Biotechnology Co., Ltd. 62
ShangHai YuanYe Biotechnology Co., Ltd. 60
Chengdu Forest Science and Technology Development Co., Ltd. 58
Shanghai Ruji Biology Technology Co., Ltd. 55

View Latest Price from Deoxynojirimycin hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Deoxynojirimycin hydrochloride pictures 2026-09-17 Deoxynojirimycin hydrochloride
73285-50-4
 10G 98%min 30kg/month WUHAN FORTUNA CHEMICAL CO., LTD
Deoxynojirimycin Hydrochloride pictures 2026-09-17 Deoxynojirimycin Hydrochloride
73285-50-4
 1KG 99.9% HPLC 20 T Suzhou Sanyi Chemical Co., Ltd.
Deoxynojirimycin hydrochloride; DNJ pictures 2026-09-11 Deoxynojirimycin hydrochloride; DNJ
73285-50-4
 1KG ≥98% HPLC 1000KG Changsha Staherb Natural Ingredients Co., Ltd.

Deoxynojirimycin hydrochloride Spectrum

Deoxynojirimycin hydrochloride(73285-50-4)1HNMR

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DEOXYNOJIRIMICIN DEOXYNOJIRIMYCIN HYDROCHLORIDE DNJ, HCL DNM (2R,3R,4R,5S)-2-(HYDROXYMETHYL)-3,4,5-PIPERIDINETRIOL (+)-1-DEOXYNOJIRIMYCIN HYDROCHLORIDE 1-DEOXYNOJIRIMYCIN HYDROCHLORIDE 1,5-DIDEOXY-1,5-IMINO-D-SORBITOL HYDROCHLORIDE 1,5-DIDEOXY-1,5-IMINO-D-GLUCITOL HYDROCHLORIDE DNJ，1-Deoxynojirimycin 1-Deoxynojirimycin hydrochloride,1,5-Dideoxy-1,5-imino-D-sorbitol hydrochloride (2R,3R,4R,5S)-2-(HydroxyMethyl)-3,4,5-piperidinetriol Hydrochloride AT 2220 Duvoglustat Hydrochloride Moranoline Hydrochloride (2R,3R,4R,5S)-2-(hydroxyMethyl)piperidine-3,4,5-triol hydrochloride Anti-Dynamin-1, C-Terminal antibody produced in rabbit DeoxynojirimycinHCl DNJ Hydrochloride 3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, hydrochloride, (2R,3R,4R,5S)- B-dynamin DNM1 Dynamin BREDNM19 3,4,5-Piperidinetriol,2-(hydroxymethyl)-, hydrochloride (1:1), (2R,3R,4R,5S)- 1-Deoxynojirimycin, Hydrochloride - CAS 73285-50-4 - Calbiochem Deoxynojirimycin hydrochloride USP/EP/BP 1-Deoxynojirimycin hydrochloride, 10 mM in DMSO Desoxynojirimycine hydrochloride 1-Deoxynojirimycin hydrochloride (Synonyms: Duvoglustat hydrochloride) 1-DNJ DEOXYNOJIRIMYCIN DNJ 73285-50-4 BioChemical Antibiotics Antibiotics A to Z Antibiotics A-F All Inhibitors Inhibitors