1,2-Benzenediamine,3,4,5-trifluoro-(9CI)
- CAS No.
- 168966-54-9
- Chemical Name:
- 1,2-Benzenediamine,3,4,5-trifluoro-(9CI)
- Synonyms
- 3,4,5-Trifluorobenzene-1,2-diamine;1,2-Benzenediamine, 3,4,5-trifluoro-;1,2-Benzenediamine,3,4,5-trifluoro-(9CI);3,4,5-Trifluorophenylene-1,2-diamine, 1,2-Diamino-3,4,5-trifluorobenzene
- CBNumber:
- CB21290130
- Molecular Formula:
- C6H5F3N2
- Molecular Weight:
- 162.11
- MDL Number:
- MFCD01569524
- MOL File:
- 168966-54-9.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2921511990 |
1,2-Benzenediamine,3,4,5-trifluoro-(9CI) price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC3920 | 3,4,5-Trifluorobenzene-1,2-diamine ≥95% | 168966-54-9 | 1g | $117 | 2026-06-04 | Buy |
| Activate Scientific | AS110810 | 3,4,5-Trifluorobenzene-1,2-diamine 96% | 168966-54-9 | 1g | $136 | 2026-06-04 | Buy |
| Activate Scientific | AS110810 | 3,4,5-Trifluorobenzene-1,2-diamine 96% | 168966-54-9 | 5g | $516 | 2026-06-04 | Buy |
| Matrix Scientific | 299149 | 3,4,5-Trifluorobenzene-1,2-diamine | 168966-54-9 | 250.00mg | $39 | 2026-05-19 | Buy |
| Matrix Scientific | 299149 | 3,4,5-Trifluorobenzene-1,2-diamine | 168966-54-9 | 1.00g | $91 | 2026-05-19 | Buy |
1,2-Benzenediamine,3,4,5-trifluoro-(9CI) Chemical Properties, Uses, Production
Synthesis
148416-38-0
168966-54-9
General procedure for the synthesis of 3,4,5-trifluoro-1,2-diaminobenzene from 2,3,4-trifluoro-6-nitroaniline: Concentrated hydrochloric acid (15 mL) was slowly added dropwise to a mixture containing 2,3,4-trifluoro-6-nitroaniline (12 mmol) and tin powder (30 mmol). The reaction mixture was heated to reflux for 1.5 hours and subsequently cooled to room temperature. The reaction mixture was neutralized with 50% sodium hydroxide solution to pH 9-10. the precipitate was collected by filtration, dried and extracted with hot ethyl acetate (80 mL). After evaporation of the filtrate, 3,4,5-trifluoro-1,2-phenylenediamine (product 10) and possible by-products were obtained. 3,4,5-trifluoro-1,2-phenylenediamine (10) was obtained in a yield of 1.40 g (70% yield); brown crystals in appearance; melting point of 85-87 °C; and thin layer chromatography (TLC) Rf value of 0.72.
References
[1] Synthesis (Germany), 2016, vol. 48, # 3, p. 394 - 406
[2] Journal of Medicinal Chemistry, 1995, vol. 38, # 22, p. 4367 - 4379
1,2-Benzenediamine,3,4,5-trifluoro-(9CI) Preparation Products And Raw materials
1,2-Benzenediamine,3,4,5-trifluoro-(9CI) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9510 | 58 |
| Changzhou Anxuan Chemical, Co., Ltd. | 13912302692 | sales@anxuanchem.com | China | 4824 | 58 |
| Aikon International Limited | 025-58859352 19370895928 | sales01@aikonchem.com | China | 15078 | 58 |
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| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +86-18949823763 | sales@tnjchem.com | China | 25333 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| Henan Lien Chemical Products Co., Ltd. | 0371-63357898 15378766539 | 535046669@qq.com | China | 5744 | 58 |
| Changzhou Kechem Bio-Scientific Co., LTD. | 0519-68985668 13685222090 | sales@kechem.cn | China | 26012 | 58 |
| Henan Weitesi Chemical Technology Co. LTD | 0371-55135753 18003832934 | 3842570495@qq.com | China | 9993 | 58 |
| Energy Chemical | 400-0056266 | marketing1@energy-chemical.com | China | 44927 | 58 |
