1,2-Diamino-4,5-difluorobenzene
- CAS No.
- 76179-40-3
- Chemical Name:
- 1,2-Diamino-4,5-difluorobenzene
- Synonyms
- 4,5-Difluorobenzene-1,2-diamine;1,2-Diamino-4,5-difluorobenzene;EA358;4,5-Difluoro-2-PhenylenediaMin;4,5-Difluoro-o-phenylenediamine;4,5-Difluoro-1,2-benzenediamine;2-AMINO-4,5-DIFLUOROPHENYLAMINE;4,5-Difluoro-2-PhenylenediaMine;4,5-Difluorophenylene-1,2-diamine;1,2-Benzenediamine, 4,5-difluoro-
- CBNumber:
- CB51119494
- Molecular Formula:
- C6H6F2N2
- Molecular Weight:
- 144.12
- MDL Number:
- MFCD00061131
- MOL File:
- 76179-40-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 132 °C |
|---|---|
| Boiling point | 282.2±35.0 °C(Predicted) |
| Density | 1.407±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| form | powder to crystal |
| pka | 3.51±0.10(Predicted) |
| color | White to Brown |
| InChI | InChI=1S/C6H6F2N2/c7-3-1-5(9)6(10)2-4(3)8/h1-2H,9-10H2 |
| InChIKey | PPWRHKISAQTCCG-UHFFFAOYSA-N |
| SMILES | C1(N)=CC(F)=C(F)C=C1N |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Risk Statements | 36/37/39 | |||||||||
| Safety Statements | 24-36/37 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| HS Code | 29215900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
1,2-Diamino-4,5-difluorobenzene price More Price(71)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | D3729 | 4,5-Difluoro-1,2-phenylenediamine >97.0%(GC)(T) | 76179-40-3 | 1g | $24 | 2026-04-30 | Buy |
| Biosynth | FD40751 | 1,2-Diamino-4,5-difluoRobenzene | 76179-40-3 | 5g | $900 | 2026-06-04 | Buy |
| Biosynth | FD40751 | 1,2-Diamino-4,5-difluoRobenzene | 76179-40-3 | 50g | $900 | 2026-06-04 | Buy |
| Biosynth | FD40751 | 1,2-Diamino-4,5-difluoRobenzene | 76179-40-3 | 25g | $900 | 2026-06-04 | Buy |
| Biosynth | FD40751 | 1,2-Diamino-4,5-difluoRobenzene | 76179-40-3 | 10g | $900 | 2026-06-04 | Buy |
1,2-Diamino-4,5-difluorobenzene Chemical Properties,Uses,Production
Application
4,5-Difluorobenzene-1,2-diamine is an organic synthesis intermediate and a chemical and pharmaceutical intermediate, which can be used in the research and development of organic synthesis reactions in laboratories and in the research and development of chemical and pharmaceutical products.
Chemical Properties
White powder
Synthesis
78056-39-0
76179-40-3
General procedure for the synthesis of 4,5-difluorophthalimide from 2-nitro-4,5-difluoroaniline: 4,5-difluoro-2-nitroaniline (10 g, 57 mmol) was co-suspended in methanol (150 mL) with 10% palladium carbon catalyst (2.0 g, 1.9 mmol). The reaction system was transferred to a hydrogenation unit and the catalytic hydrogenation reaction was carried out under 50 psi hydrogen pressure. After 3 hours of reaction, the catalyst was removed by filtration through a diatomaceous earth pad and the filtrate was concentrated under reduced pressure to give a solid product. The resulting solid was dried under vacuum at room temperature overnight to obtain white crystalline 4,5-difluorophthalimide (8.05 g, 98% yield).
References
[1] Journal of Medicinal Chemistry, 1993, vol. 36, # 3, p. 331 - 342
[2] Patent: US2005/43292, 2005, A1. Location in patent: Page/Page column 14
[3] Patent: EP2766359, 2016, B1. Location in patent: Paragraph 0755
[4] Journal of Medicinal Chemistry, 1997, vol. 40, # 5, p. 811 - 818
[5] Russian Journal of Organic Chemistry, 2001, vol. 37, # 4, p. 564 - 569
1,2-Diamino-4,5-difluorobenzene Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Harvest Chemical Industrial Co., Ltd. | 15721252604 17321035817 | sales@harvest-chem.com | China | 2829 | 64 |
| Changzhou Tianrui Pharmaceutical Technology Co., Ltd. | 0519-85386832 13382812559 | sales@cztrchem.com | China | 1211 | 56 |
| Changzhou Anxuan Chemical, Co., Ltd. | 13912302692 | sales@anxuanchem.com | China | 4824 | 58 |
| JInan Carbon Spring New Materials Co., Ltd. | 13658618215 | 308410472@qq.com | China | 58 | 58 |
| chengqiaotech.ltd | 0533-2196219; 13864320634 | lijindu01@163.com | China | 195 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
View Lastest Price from 1,2-Diamino-4,5-difluorobenzene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 1,2-DIAMINO-4,5-DIFLUOROBENZENE
76179-40-3
|
$1.00-50.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-08-25 | 1,2-DIAMINO-4,5-DIFLUOROBENZENE
76179-40-3
|
$55.00-550.00 | 10kg | 0.99 | 20tons | Zibo Hangyu Biotechnology Development Co., Ltd | |
 |
2026-03-20 | 1,2-Diamino-4,5-difluorobenzene
76179-40-3
|
$10.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- 1,2-DIAMINO-4,5-DIFLUOROBENZENE
76179-40-3
- $1.00-50.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 1,2-DIAMINO-4,5-DIFLUOROBENZENE
76179-40-3
- $55.00-550.00
- 0.99
- Zibo Hangyu Biotechnology Development Co., Ltd
-
- 1,2-Diamino-4,5-difluorobenzene
76179-40-3
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
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