2-Methoxy-6-(methylamino)pyridine
- CAS No.
- 88569-83-9
- Chemical Name:
- 2-Methoxy-6-(methylamino)pyridine
- Synonyms
- 2-METHOXY-6-METHYLPYRIDINE;m131;2-METHOXY-6-PICOLINE;6-METHOXY-2-PICOLINE;methoxymethylaminopyridine;2-Methoxy-6-(methylamino)pyridine;6-Methoxy-N-methyl-2-pyridinamine;N-Methyl-2-aMino-6-Methoxypyridine;2-Methoxy-6-methylaminopyridine>2-PYRIDINAMINE, 6-METHOXY-N-METHYL-
- CBNumber:
- CB2131579
- Molecular Formula:
- C7H10N2O
- Molecular Weight:
- 138.17
- MDL Number:
- MFCD00191557
- MOL File:
- 88569-83-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Methoxy-6-methylaminopyridine >98.0%(GC)(T) | M1185 | 25g | $123 |
| 2-Methoxy-6-methylaminopyridine 97% | AS213652 | 1g | $25 |
| 2-Methoxy-6-methylaminopyridine 97% | AS213652 | 5g | $56 |
| 2-Methoxy-6-methylaminopyridine 97% | AS213652 | 25g | $160 |
| 2-Methoxy-6-methylaminopyridine 97% | AS213652 | 100g | $433 |
| More product size | |||
| Boiling point | 231.5±25.0 °C(Predicted) |
|---|---|
| Density | 1,09 g/cm3 |
| refractive index | 1.5595 |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| pka | 5.04±0.10(Predicted) |
| form | clear liquid |
| color | Colorless to Light orange to Yellow |
| InChI | InChI=1S/C7H10N2O/c1-8-6-4-3-5-7(9-6)10-2/h3-5H,1-2H3,(H,8,9) |
| InChIKey | GXHQLRBOZRJHPZ-UHFFFAOYSA-N |
| SMILES | C1(NC)=NC(OC)=CC=C1 |
| CAS DataBase Reference | 88569-83-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 36/37/38-43-22 | |||||||||
| Safety Statements | 26-36-36/37 | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
2-Methoxy-6-(methylamino)pyridine price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | M1185 | 2-Methoxy-6-methylaminopyridine >98.0%(GC)(T) | 88569-83-9 | 25g | $123 | 2023-01-07 | Buy |
| Activate Scientific | AS213652 | 2-Methoxy-6-methylaminopyridine 97% | 88569-83-9 | 1g | $25 | 2026-06-04 | Buy |
| Activate Scientific | AS213652 | 2-Methoxy-6-methylaminopyridine 97% | 88569-83-9 | 5g | $56 | 2026-06-04 | Buy |
| Activate Scientific | AS213652 | 2-Methoxy-6-methylaminopyridine 97% | 88569-83-9 | 25g | $160 | 2026-06-04 | Buy |
| Activate Scientific | AS213652 | 2-Methoxy-6-methylaminopyridine 97% | 88569-83-9 | 100g | $433 | 2026-06-04 | Buy |
2-Methoxy-6-(methylamino)pyridine Chemical Properties,Uses,Production
Uses
2-Methoxy-6-(methylamino)pyridine is used as an intermediate ingredient in the synthesis of Liranaftate, a topical antifungal agent used primarily for the treatment of skin infections caused by fungi.
Synthesis
17228-64-7
74-89-5
88569-83-9
General procedure for the synthesis of 2-methoxy-6-(methylamino)pyridine from 2-chloro-6-methoxypyridine and monomethylamine: 2-chloro-6-methoxypyridine (12.0 g, 85.6 mmol) was mixed with 40% aqueous methanamine (24 mL) in a sealed tube and reacted for 7 hr at 170 °C. After completion of the reaction, it was cooled to room temperature and the reaction mixture was diluted with 50 mL of water and subsequently extracted with dichloromethane (3 x 50 mL). The organic layers were combined, washed sequentially with 100 mL of water and 100 mL of brine, dried over anhydrous magnesium sulfate and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (100-200 mesh, eluent 0 to 5% dichloromethane solution in methanol) to afford 6-methoxy-N-methylpyridin-2-amine (2.7 g, 31% yield) as a light yellow oil.1H NMR (400 MHz, CDCl3) δ 7.37 (t, J = 8.0 Hz, 1H), 6.04 (d, J = 8.0 Hz, 1H), 5.94 (d, J = 7.8 Hz, 1H), 4.39 (br. s, 1H), 3.86 (s, 3H), 2.90 (s, 3H).
References
[1] Patent: WO2018/73193, 2018, A1. Location in patent: Page/Page column 49
2-Methoxy-6-(methylamino)pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14036 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21533 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 | info@tnjchem.com | China | 2984 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2949 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17339 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-17392587031 | 1059@dideu.com | China | 9984 | 58 |
| AFINE CHEMICALS LIMITED | +86-571-85134551 +86-18958018566 | info@afinechem.com | China | 15058 | 58 |
View Lastest Price from 2-Methoxy-6-(methylamino)pyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-03-20 | 2-Methoxy-6-(methylamino)pyridine
88569-83-9
|
$10.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
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2025-06-25 | 2-Methoxy-6-(methylamino)pyridine
88569-83-9
|
$1.10 | 1g | 99.0% min | 100 tons min | Shaanxi Dideu Medichem Co. Ltd | |
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2019-07-06 | 2-Methoxy-6-(methylamino)pyridine
88569-83-9
|
$1.00 | 1kg | 99% | Career Henan Chemical Co |
-

- 2-Methoxy-6-(methylamino)pyridine
88569-83-9
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-

- 2-Methoxy-6-(methylamino)pyridine
88569-83-9
- $1.10
- 99.0% min
- Shaanxi Dideu Medichem Co. Ltd
-

- 2-Methoxy-6-(methylamino)pyridine
88569-83-9
- $1.00
- 99%
- Career Henan Chemical Co





