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bruceine E

bruceine E Structure
bruceine E structure
CAS No.
21586-90-3
Chemical Name:
bruceine E
Synonyms
Brucein E;20-Deoxybruceine F;2-O-Demethylbruceine M;Bruceine E, 10 mM in DMSO;13,20-Epoxy-1β,2α,11β,12α,14,15β-hexahydroxypicras-3-en-16-one;hypoglycemia,quassinoid,Bruceine E,effect,Inhibitor,antidiabetic,inhibit;Picras-3-en-16-one, 13,20-epoxy-1,2,11,12,14,15-hexahydroxy-, (1β,2α,11β,12α,15β)-;(1R,2S,3R,3aR,3a1R,4R,6aR,7aS,10S,11S,11aS)-1,2,3a,4,10,11-hexahydroxy-3,8,11a-trimethyl-2,3,3a,4,7,7a,10,11,11a,11b-decahydro-1H-3,3a1-(epoxymethano)dibenzo[de,g]chromen-5(6aH)-one;(1R,2S,3R,3aR,3a1R,4R,6aR,7aS,10S,11S,11aS,11bR)-1,2,3a,4,10,11-Hexahydroxy-3,8,11a-trimethyl-1,2,3,3a,4,6a,7,7a,10,11,11a,11b-dodecahydro-5H-3,3a1-(epoxymethano)dibenzo[de,g]chromen-5-one
CBNumber:
CB21340189
Molecular Formula:
C20H28O9
Molecular Weight:
412.43
MDL Number:
MFCD00221754
MOL File:
21586-90-3.mol
MSDS File:
SDS
Last updated:2026-07-16 07:06:08
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bruceine E Properties

Melting point 262-263 °C
Boiling point 632.635±55.00 °C(Press: 760.00 Torr)(predicted)
Density 1.609±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka 11.502±0.70(predicted)
form Solid
color White to off-white

bruceine E price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth WAA58690 Bruceine E 21586-90-3 25mg $1267.5 2026-06-05 Buy
Biosynth WAA58690 Bruceine E 21586-90-3 50mg $1763.5 2026-06-05 Buy
Biosynth WAA58690 Bruceine E 21586-90-3 100mg $2821 2026-06-05 Buy
ChemScene CS-0022970 Bruceine E 97.32% 21586-90-3 1mg $92 2026-06-04 Buy
ChemScene CS-0022970 Bruceine E 97.32% 21586-90-3 5mg $184 2026-06-04 Buy
Product number Packaging Price Buy
WAA58690 25mg $1267.5 Buy
WAA58690 50mg $1763.5 Buy
WAA58690 100mg $2821 Buy
CS-0022970 1mg $92 Buy
CS-0022970 5mg $184 Buy

bruceine E Chemical Properties,Uses,Production

Chemical Properties

White crystalline powder, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from the fruit of Brucea javanica.

Uses

Bruceine E is a quassinoid from seeds of Brucea javanica (L.) Merr, exhibiting hypoglycemia effect[1]. Bruceine E exhibits blood glucose lowering effect in both nondiabetic mice and Streptozotocin (STZ (HY-13753))-induced diabetic rats at lower dose[2].

in vivo

Bruceine D and E, isolated from B. javanica seeds, exhibits blood glucose lowering effect in both nondiabetic mice and STZ-induced diabetic rats at lower dose (1 mg/kg b.w.) during 0-8 h screening[2].

References

[1] Man F, et al. HPLC-MS/MS method for bioavailability study of bruceines D & E in rat plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 15;1063:183-188. DOI:10.1016/j.jchromb.2017.08.037
[2] Ablat A, et al. Antidiabetic effects of Brucea javanica seeds in type 2 diabetic rats. BMC Complement Altern Med. 2017;17(1):94. Published 2017 Feb 6. DOI:10.1186/s12906-017-1610-x

bruceine E Preparation Products And Raw materials

Raw materials

Preparation Products

bruceine E Suppliers

Global( 62)Suppliers
Supplier Tel Email Country ProdList Advantage
BioBioPha Co., Ltd. 0871-65217109 y.liu@mail.biobiopha.com China 5641 65
Chengdu Biopurify Phytochemicals Ltd. +86-028-82633397 18982077548 cwb1@biopurify.cn China 2376 60
Shanghai Tauto Biotech Co., Ltd. 021-51320588 tauto@tautobiotech.com China 3984 66
Shanghai Zhanshu Chemical Technology Co., Ltd +86-21-58589556 China 413 55
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7717 56
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632; sales@reading-chemicals.com China 15165 58
Wuhan ChemFaces Biochemical Co., Ltd. 18607101326 15172504745 aileen@chemfaces.com China 6904 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Chengdu Push Bio-Technology Co., Ltd. 028-85370565-229 18080489829 18080489829@163.com China 8379 60
Shanghai Standard Technology Co.,Ltd. 021-021-57127007-6622-6622 17621252073 luzh@nature-standard.com China 3021 58
Supplier Advantage
BioBioPha Co., Ltd. 65
Chengdu Biopurify Phytochemicals Ltd. 60
Shanghai Tauto Biotech Co., Ltd. 66
Shanghai Zhanshu Chemical Technology Co., Ltd 55
Sichuan Wei Keqi Biological Technology Co., Ltd. 56
Wuxi Zhongkun Biochemical Technology Co., Ltd. 58
Wuhan ChemFaces Biochemical Co., Ltd. 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
Chengdu Push Bio-Technology Co., Ltd. 60
Shanghai Standard Technology Co.,Ltd. 58

View Lastest Price from bruceine E manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Bruceine E pictures 2026-07-15 Bruceine E
21586-90-3
 $46.00-163.00 99.88% 10g TargetMol Chemicals Inc.
bruceine E pictures 2020-01-19 bruceine E
21586-90-3
 $3.00 1KG 98% 1kg,5kg,50kg Career Henan Chemical Co
  • Bruceine E pictures
  • Bruceine E
    21586-90-3
  • $46.00-163.00
  • 99.88%
  • TargetMol Chemicals Inc.
  • bruceine E pictures
  • bruceine E
    21586-90-3
  • $3.00
  • 98%
  • Career Henan Chemical Co

bruceine E Spectrum

bruceine E(21586-90-3)1HNMR

21586-90-3(bruceine E)Related Search:

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delta-Dodecalactone 5-Decanolide Undecanolactone 5-Hydroxyoctanoic acid lactone delta-Nonalactone
Lactic acid isoamyl ester (-)-Dihydrocarvyl acetate Dihydrocarveol 3,5,5-Trimethyl-2-cyclohexen-1-ol (R)-beta-Hydroxy-beta-methyl-delta-valerolactone
(R)-ETHYL 3-METHYL-2-HYDROXYBUTANOATE bruceine E (R)-5-HEXANOLIDE

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13,20-Epoxy-1β,2α,11β,12α,14,15β-hexahydroxypicras-3-en-16-one 20-Deoxybruceine F 2-O-Demethylbruceine M Picras-3-en-16-one, 13,20-epoxy-1,2,11,12,14,15-hexahydroxy-, (1β,2α,11β,12α,15β)- (1R,2S,3R,3aR,3a1R,4R,6aR,7aS,10S,11S,11aS)-1,2,3a,4,10,11-hexahydroxy-3,8,11a-trimethyl-2,3,3a,4,7,7a,10,11,11a,11b-decahydro-1H-3,3a1-(epoxymethano)dibenzo[de,g]chromen-5(6aH)-one hypoglycemia,quassinoid,Bruceine E,effect,Inhibitor,antidiabetic,inhibit (1R,2S,3R,3aR,3a1R,4R,6aR,7aS,10S,11S,11aS,11bR)-1,2,3a,4,10,11-Hexahydroxy-3,8,11a-trimethyl-1,2,3,3a,4,6a,7,7a,10,11,11a,11b-dodecahydro-5H-3,3a1-(epoxymethano)dibenzo[de,g]chromen-5-one Bruceine E, 10 mM in DMSO Brucein E 21586-90-3