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bruceine E

bruceine E structure

CAS No.: 21586-90-3

Chemical Name:: bruceine E

Synonyms: Brucein E;20-Deoxybruceine F;2-O-Demethylbruceine M;Bruceine E, 10 mM in DMSO;13,20-Epoxy-1β,2α,11β,12α,14,15β-hexahydroxypicras-3-en-16-one;hypoglycemia,quassinoid,Bruceine E,effect,Inhibitor,antidiabetic,inhibit;Picras-3-en-16-one, 13,20-epoxy-1,2,11,12,14,15-hexahydroxy-, (1β,2α,11β,12α,15β)-;(1R,2S,3R,3aR,3a1R,4R,6aR,7aS,10S,11S,11aS)-1,2,3a,4,10,11-hexahydroxy-3,8,11a-trimethyl-2,3,3a,4,7,7a,10,11,11a,11b-decahydro-1H-3,3a1-(epoxymethano)dibenzo[de,g]chromen-5(6aH)-one;(1R,2S,3R,3aR,3a1R,4R,6aR,7aS,10S,11S,11aS,11bR)-1,2,3a,4,10,11-Hexahydroxy-3,8,11a-trimethyl-1,2,3,3a,4,6a,7,7a,10,11,11a,11b-dodecahydro-5H-3,3a1-(epoxymethano)dibenzo[de,g]chromen-5-one

CBNumber:: CB21340189

Molecular Formula:: C20H28O9

Molecular Weight:: 412.43

MDL Number:: MFCD00221754

MOL File:: 21586-90-3.mol

MSDS File:: SDS

Last updated:2026-05-11 16:31:51

Product description	Number	Pack Size	Price
Bruceine E	WAA58690	25mg	$1267.5
Bruceine E	WAA58690	50mg	$1763.5
Bruceine E	WAA58690	100mg	$2821
Bruceine E 97.32%	CS-0022970	1mg	$92
Bruceine E 97.32%	CS-0022970	5mg	$184

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bruceine E Properties

form	Solid
color	White to off-white

bruceine E price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth	WAA58690	Bruceine E	21586-90-3	25mg	$1267.5	2026-06-05	Buy
Biosynth	WAA58690	Bruceine E	21586-90-3	50mg	$1763.5	2026-06-05	Buy
Biosynth	WAA58690	Bruceine E	21586-90-3	100mg	$2821	2026-06-05	Buy
ChemScene	CS-0022970	Bruceine E 97.32%	21586-90-3	1mg	$92	2026-06-04	Buy
ChemScene	CS-0022970	Bruceine E 97.32%	21586-90-3	5mg	$184	2026-06-04	Buy

Product number	Packaging	Price	Buy
WAA58690	25mg	$1267.5	Buy
WAA58690	50mg	$1763.5	Buy
WAA58690	100mg	$2821	Buy
CS-0022970	1mg	$92	Buy
CS-0022970	5mg	$184	Buy

bruceine E Chemical Properties,Uses,Production

Chemical Properties

White crystalline powder, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from the fruit of Brucea javanica.

Uses

Bruceine E is a quassinoid from seeds of Brucea javanica (L.) Merr, exhibiting hypoglycemia effect[1]. Bruceine E exhibits blood glucose lowering effect in both nondiabetic mice and Streptozotocin (STZ (HY-13753))-induced diabetic rats at lower dose[2].

in vivo

Bruceine D and E, isolated from B. javanica seeds, exhibits blood glucose lowering effect in both nondiabetic mice and STZ-induced diabetic rats at lower dose (1 mg/kg b.w.) during 0-8 h screening^[2].

References

[1] Man F, et al. HPLC-MS/MS method for bioavailability study of bruceines D & E in rat plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 15;1063:183-188. DOI:10.1016/j.jchromb.2017.08.037
[2] Ablat A, et al. Antidiabetic effects of Brucea javanica seeds in type 2 diabetic rats. BMC Complement Altern Med. 2017;17(1):94. Published 2017 Feb 6. DOI:10.1186/s12906-017-1610-x

bruceine E Preparation Products And Raw materials

Raw materials

Preparation Products

bruceine E Suppliers

Global( 62)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Chengdu Biopurify Phytochemicals Ltd.	+86-28-82633860; +8618080483897	sales@biopurify.com	China	4616	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
Wuhan ChemNorm Biotech Co.,Ltd.	+86-27-8439 4403 18971486879	sales@chemnorm.com	CHINA	2935	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19853	58
Labnetwork lnc.	+86-27-50766799 +8618062016861	contact@labnetwork.com	China	19987	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39039	58
Mensura Group Limited	18780014153	1058503172@qq.com	China	2900	58
BioBioPha Co., Ltd.	0871-65217109 13211707573;	y.liu@mail.biobiopha.com	China	5645	65
Chengdu Biopurify Phytochemicals Ltd.	+86-028-82633397 18982077548	cwb1@biopurify.cn	China	2376	60

Supplier	Advantage
Chengdu Biopurify Phytochemicals Ltd.	58
career henan chemical co	58
Wuhan ChemNorm Biotech Co.,Ltd.	58
TargetMol Chemicals Inc.	58
BOC Sciences	58
Labnetwork lnc.	58
TargetMol Chemicals Inc.	58
Mensura Group Limited	58
BioBioPha Co., Ltd.	65
Chengdu Biopurify Phytochemicals Ltd.	60

View Lastest Price from bruceine E manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-05-11	Bruceine E 21586-90-3	$46.00-163.00		99.88%	10g	TargetMol Chemicals Inc.
	2020-01-19	bruceine E 21586-90-3	$3.00	1KG	98%	1kg,5kg,50kg	Career Henan Chemical Co

Bruceine E
21586-90-3
$46.00-163.00
99.88%
TargetMol Chemicals Inc.

bruceine E
21586-90-3
$3.00
98%
Career Henan Chemical Co

bruceine E Spectrum

bruceine E(21586-90-3)¹HNMR

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13,20-Epoxy-1β,2α,11β,12α,14,15β-hexahydroxypicras-3-en-16-one 20-Deoxybruceine F 2-O-Demethylbruceine M Picras-3-en-16-one, 13,20-epoxy-1,2,11,12,14,15-hexahydroxy-, (1β,2α,11β,12α,15β)- (1R,2S,3R,3aR,3a1R,4R,6aR,7aS,10S,11S,11aS)-1,2,3a,4,10,11-hexahydroxy-3,8,11a-trimethyl-2,3,3a,4,7,7a,10,11,11a,11b-decahydro-1H-3,3a1-(epoxymethano)dibenzo[de,g]chromen-5(6aH)-one hypoglycemia,quassinoid,Bruceine E,effect,Inhibitor,antidiabetic,inhibit (1R,2S,3R,3aR,3a1R,4R,6aR,7aS,10S,11S,11aS,11bR)-1,2,3a,4,10,11-Hexahydroxy-3,8,11a-trimethyl-1,2,3,3a,4,6a,7,7a,10,11,11a,11b-dodecahydro-5H-3,3a1-(epoxymethano)dibenzo[de,g]chromen-5-one Bruceine E, 10 mM in DMSO Brucein E 21586-90-3