1-Iodo-3,5-dimethylbenzene
- CAS No.
- 22445-41-6
- Chemical Name:
- 1-Iodo-3,5-dimethylbenzene
- Synonyms
- 5-IODO-M-XYLENE;5-Iodo-m-xylene,99%;1-Iodo-3,5-dimethyL;3,5-DIMETHYLIODOBENZENE;3,5-Dinethyliodobenzene;3,5-dimethylphenyl iodide;5-Iodo-M-xylene, 99% 25ML;3,5-diMethyl-1-iodobenzene;1-IODO-3,5-DIMETHYLBENZENE;1,3-DIMETHYL-5-IODOBENZENE
- CBNumber:
- CB2135658
- Molecular Formula:
- C8H9I
- Molecular Weight:
- 232.06
- MDL Number:
- MFCD00060659
- MOL File:
- 22445-41-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1-Iodo-3,5-dimethylbenzene 99% | 392510 | 5ml | $57.26 |
| 1-Iodo-3,5-dimethylbenzene 99% | 392510 | 25ml | $133 |
| 5-Iodo-m-xylene | I0548 | 5G | $60 |
| 5-Iodo-m-xylene | I0548 | 25G | $180 |
| 1-Iodo-3,5-dimethylbenzene | I705518 | 10g | $75 |
| More product size | |||
| Melting point | -2.9°C (estimate) |
|---|---|
| Boiling point | 92-94 °C3 mm Hg(lit.) |
| Density | 1.608 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Sparingly soluble (0.014 g/L) (25°C), Calc. |
| form | Liquid |
| Specific Gravity | 1.608 |
| color | Clear light yellow |
| Sensitive | Light Sensitive |
| BRN | 2039353 |
| InChI | 1S/C8H9I/c1-6-3-7(2)5-8(9)4-6/h3-5H,1-2H3 |
| InChIKey | ZLMKEENUYIUKKC-UHFFFAOYSA-N |
| SMILES | Cc1cc(C)cc(I)c1 |
| CAS DataBase Reference | 22445-41-6(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzene, 1-iodo-3,5-dimethyl-(22445-41-6) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi,C | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29039990 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
1-Iodo-3,5-dimethylbenzene price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 392510 | 1-Iodo-3,5-dimethylbenzene 99% | 22445-41-6 | 5ml | $57.26 | 2025-07-31 | Buy |
| Sigma-Aldrich | 392510 | 1-Iodo-3,5-dimethylbenzene 99% | 22445-41-6 | 25ml | $133 | 2025-07-31 | Buy |
| TCI Chemical | I0548 | 5-Iodo-m-xylene | 22445-41-6 | 5G | $60 | 2025-07-31 | Buy |
| TCI Chemical | I0548 | 5-Iodo-m-xylene | 22445-41-6 | 25G | $180 | 2025-07-31 | Buy |
| TRC | I705518 | 1-Iodo-3,5-dimethylbenzene | 22445-41-6 | 10g | $75 | 2021-12-16 | Buy |
1-Iodo-3,5-dimethylbenzene Chemical Properties,Uses,Production
Chemical Properties
clear light yellow liquid
Uses
suzuki reaction
Uses
1-Iodo-3,5-dimethylbenzene (5-iodo-m-xylene) is suitable for use in the synthesis of N-(3,5-xylyl)-N-ethyl aniline, an aryl amine, It is also used in the following studies; α-Arylation of ketones, Copper-catalyzed N-arylation of imidazoles, Cyanation of 5-iodo-m-xylene to form 3,5-dimethylbenzonitrile, synthesis of 1,3-Dimethyl-5-phenoxybenzene by nano-CuFe2O4 catalyzed C-O cross-coupling with phenol, CuBr-catalyzed amination of 1-iodo-3,5-dimethylbenzene to form N-Allyl-3,5-dimethylbenzenamine, copper-catalyzed C-S bond-formation between 5-iodo-m-xylene and thiophenol. It is also employed as a starting material in the synthesis of biphenyl-3,3?,5,5?-tetracarboxylic acid, radical bromination of 5-iodo-m-xylene by N-bromosuccinimide to form 1,3-bis(bromomethyl)-5-iodobenzene.
Uses
1-Iodo-3,5-dimethylbenzene (5-iodo-m-xylene) is suitable for use in the synthesis of N-(3,5-xylyl)-N-ethylaniline, an arylamine.
It may be used in the following studies:
- α-Arylation of ketones.
- Copper-catalyzed N-arylation of imidazoles.
- Cyanation of 5-iodo-m-xylene to form 3,5-dimethylbenzonitrile.
- Synthesis of 1,3-Dimethyl-5-phenoxybenzene by nano-CuFe2O4 catalyzed C-O cross-coupling with phenol.
- CuBr-catalyzed amination of 1-iodo-3,5-dimethylbenzene to form N-Allyl-3,5-dimethylbenzenamine.
- Copper-catalyzed C-S bond-formation between 5-iodo-m-xylene and thiophenol.
- As a starting material in the synthesis of biphenyl-3,3′,5,5′-tetracarboxylic acid.
- Radical bromination of 5-iodo-m-xylene by N-bromosuccinimide to form 1,3-bis(bromomethyl)-5-iodobenzene.
General Description
1-Iodo-3,5-dimethylbenzene (5-Iodo-m-xylene) is an aryl halide. It can be obtained from 5-bromo-m-xylene, via copper-catalyzed halogen exchange reaction, in the presence of NaI or KI in n-BuOH or DMF (solvents). It undergoes reaction with phenol in the presence of CuFe2O4 nano powder as a recyclable catalyst to afford 1,3-dimethyl-5-phenoxybenzene.
1-Iodo-3,5-dimethylbenzene Preparation Products And Raw materials
Raw materials
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Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8753 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20128 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Speranza Chemical Co., Ltd. | +86-86-075521030354 +8618688942810 | sophieliu@speranzachem.com | China | 923 | 55 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2972 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-17392712697 | 1022@dideu.com | China | 3995 | 58 |
View Lastest Price from 1-Iodo-3,5-dimethylbenzene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-01-23 | 1-iodo-3,5-dimethylbenzene
22445-41-6
|
US $460.00 / KG | 1KG | 98% | 300MT/year | Speranza Chemical Co., Ltd. | |
 |
2026-01-05 | 1-Iodo-3,5-dimethylbenzene
22445-41-6
|
US $0.00-0.00 / KG | 1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-12-24 | 1-Iodo-3,5-dimethylbenzene
22445-41-6
|
US $0.10 / KG | 1KG | 99.0% | 1000 tons | Shaanxi Dideu Medichem Co. Ltd |
-
- 1-iodo-3,5-dimethylbenzene
22445-41-6
- US $460.00 / KG
- 98%
- Speranza Chemical Co., Ltd.
-
- 1-Iodo-3,5-dimethylbenzene
22445-41-6
- US $0.00-0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 1-Iodo-3,5-dimethylbenzene
22445-41-6
- US $0.10 / KG
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
