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3,5-Dimethylphenylboronic acid

3,5-Dimethylphenylboronic acid structure

CAS No.: 172975-69-8

Chemical Name:: 3,5-Dimethylphenylboronic acid

Synonyms: AKOS BRN-0067;TIMTEC-BB SBB004076;RARECHEM AH PB 0186;3,5-Dimethyl benzene;3,5-Dimethylphenylbo;M-XYLENE-5-BORONIC ACID;3,5 Dimethyl Boronic Acid;3,5-dimethylphenylboronic v;3,5-Dimethylphenylboronicaci;3,5-DIMETHYLPHENYLBORONIC ACID

CBNumber:: CB6219192

Molecular Formula:: C8H11BO2

Molecular Weight:: 149.98

MDL Number:: MFCD00185689

MOL File:: 172975-69-8.mol

MSDS File:: SDS

Last updated:2026-05-28 03:20:30

Product description	Number	Pack Size	Price
3,5-Dimethylphenylboronic acid ≥95.0%	480088	5g	$65.2
3,5-Dimethylphenylboronic acid ≥95.0%	480088	25g	$310
3,5-Dimethylphenylboronic Acid (contains varying amounts of Anhydride)	D3396	5g	$38
3,5-Dimethylphenylboronic Acid (contains varying amounts of Anhydride)	D3396	25g	$152
3,5-Dimethylphenylboronic acid	FD139300	0.25kg	$900
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3,5-Dimethylphenylboronic acid Properties

Melting point	261-265 °C (lit.)
Boiling point	312.7±52.0 °C(Predicted)
Density	1.07±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
Water Solubility	Slightly soluble in water
form	solid
pka	8.72±0.10(Predicted)
color	White to Orange to Green
BRN	7368658
InChI	InChI=1S/C8H11BO2/c1-6-3-7(2)5-8(4-6)9(10)11/h3-5,10-11H,1-2H3
InChIKey	DJGHSJBYKIQHIK-UHFFFAOYSA-N
SMILES	B(C1=CC(C)=CC(C)=C1)(O)O
CAS DataBase Reference	172975-69-8(CAS DataBase Reference)
UNSPSC Code	12352103
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

PPE

Eyeshields, Gloves, type N95 (US)

Hazard Codes

Xn,Xi

Risk Statements

22-36/37/38

Safety Statements

37/39-26-36/37

WGK Germany

HazardClass

IRRITANT

HS Code

29319090

Storage Class

11 - Combustible Solids

REACH Registrations

Active

NFPA 704

	0
2		0

3,5-Dimethylphenylboronic acid price More Price(80)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	480088	3,5-Dimethylphenylboronic acid ≥95.0%	172975-69-8	5g	$65.2	2023-06-20	Buy
Sigma-Aldrich	480088	3,5-Dimethylphenylboronic acid ≥95.0%	172975-69-8	25g	$310	2023-01-07	Buy
TCI Chemical	D3396	3,5-Dimethylphenylboronic Acid (contains varying amounts of Anhydride)	172975-69-8	5g	$38	2026-04-30	Buy
TCI Chemical	D3396	3,5-Dimethylphenylboronic Acid (contains varying amounts of Anhydride)	172975-69-8	25g	$152	2026-04-30	Buy
Biosynth	FD139300	3,5-Dimethylphenylboronic acid	172975-69-8	0.25kg	$900	2026-06-04	Buy

Product number	Packaging	Price	Buy
480088	5g	$65.2	Buy
480088	25g	$310	Buy
D3396	5g	$38	Buy
D3396	25g	$152	Buy
FD139300	0.25kg	$900	Buy

3,5-Dimethylphenylboronic acid Chemical Properties,Uses,Production

Chemical Properties

off-white to light yellow crystalline powder

Uses

suzuki reaction

Uses

3,5-Dimethylphenylboronic Acid is a useful research intermediate for organic synthesis

Uses

3,5-Dimethylphenylboronic acid (DMPBA) can be used as:

A reactant in the palladium-catalyzed Suzuki coupling reactions.
A co-extractant in the combination with modified Aliquat 336 for the extraction of xylose, glucose, and fructose from aqueous solutions.
A reactant to prepare penultimate methyl ester.

Synthesis

67-56-1

55124-35-1

556-96-7

172975-69-8

GENERAL PROCEDURE: A 1 M THF solution (375 μL, 375 μmol) of phenylmagnesium bromide (PhMgBr) was added dropwise to a tetrahydrofuran (THF, 4 mL) solution of diisopropylaminoborane (DIPAB, 863 mg, 7.5 mmol) and magnesium scrapings (Mg, 182 mg, 7.5 mmol) at room temperature. After 10 min of reaction, 30 mL of anhydrous THF was added, followed by 3,5-dimethylbromobenzene (5 mmol). The reaction mixture was cooled to 0 °C and quenched by slow addition of methanol (MeOH, 7 mL). After 1 h of reaction, the volatiles were removed under reduced pressure and the resulting solid was dissolved in a 1N hydrochloric acid/methanol (7:3, v/v) mixture. The reaction was continued for 1 h at room temperature, followed by the addition of ethyl acetate (AcOEt, 100 mL) for extraction. The organic phase was washed sequentially with 1N hydrochloric acid (30 mL) and saturated saline (3 x 30 mL). The organic phase was concentrated under reduced pressure to give the crude product, which was finally purified by recrystallization from water (H2O) to give 3,5-dimethylphenylboronic acid.

References

[1] Tetrahedron, 2019, vol. 75, # 2, p. 164 - 171

3,5-Dimethylphenylboronic acid synthesis

Synthesis of 3,5-Dimethylphenylboronic acid from Trimethyl borate and Water and 3,5-DIMETHYLPHENYLMAGNESIUM BROMIDE

3,5-Dimethylphenylboronic acid Preparation Products And Raw materials

Raw materials

Trimethyl borate Triisopropyl borate Methanol BORANE-DIISOPROPYLAMINE Water

3,5-DIMETHYLPHENYLMAGNESIUM BROMIDE 5-Bromo-m-xylene Magnesium Phenylmagnesium bromide Tetrahydrofuran

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Preparation Products

1-Iodo-3,5-dimethylbenzene 3,3',5,5'-TETRAMETHYLBIPHENYL 3,5-Bis(methoxycarbonyl)phenylboronic acid 2-Chloro-4-(3,5-diMethylphenyl)benzoic acid

3,5-Dimethylphenylboronic acid Suppliers

Global( 404)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20121	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	14026	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21585	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Speranza Chemical Co., Ltd.	+86-86-075521030354 +8618688942810	sophieliu@speranzachem.com	China	923	55
AB PharmaTech,LLC	323-480-4688	sales@acrospharmatech.com	United States	989	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29812	58
Shanghai Arbor Chemical Co., Ltd.	021-60451682	act@arborchemical.com	CHINA	904	58

Supplier	Advantage
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Speranza Chemical Co., Ltd.	55
AB PharmaTech,LLC	55
career henan chemical co	58
Shanghai Arbor Chemical Co., Ltd.	58

View Lastest Price from 3,5-Dimethylphenylboronic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-07-22	3,5-Dimethylphenylboronic acid 172975-69-8	$10.00	1KG	99%	300MT/year	Speranza Chemical Co., Ltd.
2026-07-21	3,5-Dimethylphenylboronic acid 172975-69-8			0.99		RongNa Biotechnology Co.,Ltd
2026-07-09	3,5-Dimethylphenylboronic acid 172975-69-8	$1.20-34.00	1kg	99%		Henan Fengda Chemical Co., Ltd

3,5-Dimethylphenylboronic acid
172975-69-8
$10.00
99%
Speranza Chemical Co., Ltd.

3,5-Dimethylphenylboronic acid
172975-69-8
0.99
RongNa Biotechnology Co.,Ltd

3,5-Dimethylphenylboronic acid
172975-69-8
$1.20-34.00
99%
Henan Fengda Chemical Co., Ltd

3,5-Dimethylphenylboronic acid Spectrum

3,5-Dimethylphenylboronic acid(172975-69-8)¹HNMR

172975-69-8(3,5-Dimethylphenylboronic acid)Related Search:

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Citric acid Ascoric Acid 4-(4′-Chlorobenzyloxy)-3,5-dimethylphenylboronic acid 3 5-DIFORMYLPHENYLBORONIC ACID 3,5-Bis(trifluoromethyl)benzeneboronic acid

(3-T-BUTYL-5-METHYLPHENYL)BORONIC ACID 2-BUTOXY-3,5-DIMETHYLPHENYLBORONIC ACID 4-(3'-CHLOROBENZYLOXY)-3,5-DIMETHYLPHEN&

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RARECHEM AH PB 0186 M-XYLENE-5-BORONIC ACID TIMTEC-BB SBB004076 3,5-Dimethyl benzene 3,5-DIMETHYLBENZENEBORONIC ACID 3,5-DIMETHYLPHENYLBORONIC ACID AKOS BRN-0067 3,5-DIMETHYLBENZENEBORONIC ACID 98% 3,5-Dimethylphenylboronic Acid (contains varying amounts of Anhydride) 3,5-Dimethylphenylboronic acid,97% 3,5-Dimethylphenylboronic acid ,98% 3,5-Dimethylphenylbo 3,5-Dimethylbenzeneboronic Acid m-Xylene-5-boronic Acid Boronic acid, B-(3,5-diMethylphenyl)- 3,5-dimethylphenylboronic v 3,5-Dimethylphenylboronicaci C8H11BO2 3,5-Dimethylphenylboronic acid 172975-69-8 3,5 Dimethyl Boronic Acid 3,5-Dimethylphenylboronic acid - [D2980] 172975-69-8 17223-69-8 BORONIC ACID Aryl Boronic Acids Boronic Acids and Derivatives Organometallic Reagents Pyridines B (Classes of Boron Compounds) Boronic Acids Boronic Acids Boronic Acids and Derivatives Aryl Organoborons Heterocyclic Compounds Boronic Acid blocks BoronicAcids Boric Acid